A novel, smaller scaffold for Affitins: Showcase with binders specific for EpCAM

Autor: Valentina Kalichuk, Véronique Préat, Gonzalo Obal, Frédéric Pecorari, Mike Maillasson, Federico Carrión, Barbara Mouratou, Ghislaine Béhar, Axelle Renodon-Cornière

Publikováno v: Biotechnology and Bioengineering
Biotechnology and Bioengineering, Wiley, 2017, Epub ahead of print. ⟨10.1002/bit.26463⟩
Biotechnology and Bioengineering, 2017, Epub ahead of print. ⟨10.1002/bit.26463⟩

International audience; Affitins are highly stable engineered affinity proteins, originally derived from Sac7d and Sso7d, two 7 kDa DNA-binding polypeptides from Sulfolobus genera. Their efficiency as reagents for intracellular targeting, enzyme inhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3faee1c79e143246d3a00a336eb44d
https://www.hal.inserm.fr/inserm-01629637/file/KalichukEq13.pdf

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