The Boltzmann distributions of molecular structures predict likely changes through random mutations.

Autor: Martin NS; Rudolf Peierls Centre for Theoretical Physics, University of Oxford, Oxford, United Kingdom; Theory of Condensed Matter Group, Cavendish Laboratory, University of Cambridge, Cambridge, United Kingdom; Sainsbury Laboratory, University of Cambridge, Cambridge, United Kingdom. Electronic address: nora.martin@crg.eu., Ahnert SE; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom; The Alan Turing Institute, London, United Kingdom.

Publikováno v: Biophysical journal [Biophys J] 2023 Nov 21; Vol. 122 (22), pp. 4467-4475. Date of Electronic Publication: 2023 Oct 29.

The non-deterministic genotype-phenotype map of RNA secondary structure.

Autor: García-Galindo P; Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge CB3 0AS, UK., Ahnert SE; Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge CB3 0AS, UK.; The Alan Turing Institute, 96 Euston Road, London NW1 2DB, UK., Martin NS; Rudolf Peierls Centre for Theoretical Physics, Beecroft Building, Parks Road, Oxford OX1 3PU, UK.

Publikováno v: Journal of the Royal Society, Interface [J R Soc Interface] 2023 Aug; Vol. 20 (205), pp. 20230132. Date of Electronic Publication: 2023 Aug 23.

Predicting phenotype transition probabilities via conditional algorithmic probability approximations.

Autor: Dingle K; Department of Chemical Engineering and Biotechnology, Cambridge University, Cambridge CB2 1TN, UK.; Department of Computing and Mathematical Sciences, California Institute of Technology, Pasadena, CA 91125, USA.; Department of Mathematics and Natural Sciences, Centre for Applied Mathematics and Bioinformatics (CAMB), Gulf University for Science and Technology, 32093, Kuwait., Novev JK; Department of Chemical Engineering and Biotechnology, Cambridge University, Cambridge CB2 1TN, UK., Ahnert SE; Department of Chemical Engineering and Biotechnology, Cambridge University, Cambridge CB2 1TN, UK., Louis AA; Department of Physics, Rudolf Peierls Centre for Theoretical Physics, Oxford University, Oxford OX1 2JD, UK.

Publikováno v: Journal of the Royal Society, Interface [J R Soc Interface] 2022 Dec; Vol. 19 (197), pp. 20220694. Date of Electronic Publication: 2022 Dec 14.

The long and winding road to understanding organismal construction: Reply to comments on "From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics".

Autor: Manrubia S; Department of Systems Biology, Centro Nacional de Biotecnología (CSIC), Madrid, Spain; Grupo Interdisciplinar de Sistemas Complejos (GISC), Madrid, Spain. Electronic address: smanrubia@cnb.csic.es., Cuesta JA; Grupo Interdisciplinar de Sistemas Complejos (GISC), Madrid, Spain; Departamento de Matemáticas, Universidad Carlos III de Madrid, Leganés, Spain; Instituto de Biocomputación y Física de Sistemas Complejos (BiFi), Universidad de Zaragoza, Spain; UC3M-Santander Big Data Institute (IBiDat), Getafe, Madrid, Spain., Aguirre J; Grupo Interdisciplinar de Sistemas Complejos (GISC), Madrid, Spain; Centro de Astrobiología, CSIC-INTA, ctra. de Ajalvir km 4, 28850 Torrejón de Ardoz, Madrid, Spain., Ahnert SE; Theory of Condensed Matter Group, Cavendish Laboratory, University of Cambridge, Cambridge, UK; Sainsbury Laboratory, University of Cambridge, Cambridge, UK., Altenberg L; University of Hawai'i at Manoa, HI, USA., Cano AV; Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Catalán P; Grupo Interdisciplinar de Sistemas Complejos (GISC), Madrid, Spain; Departamento de Matemáticas, Universidad Carlos III de Madrid, Leganés, Spain., Diaz-Uriarte R; Department of Biochemistry, Universidad Autónoma de Madrid, Madrid, Spain; Instituto de Investigaciones Biomédicas 'Alberto Sols' (UAM-CSIC), Madrid, Spain., Elena SF; Instituto de Biología Integrativa de Sistemas, I(2)SysBio (CSIC-UV), València, Spain; The Santa Fe Institute, Santa Fe, NM, USA., García-Martín JA; Centro Nacional de Biotecnología (CSIC), Madrid, Spain., Hogeweg P; Theoretical Biology and Bioinformatics Group, Utrecht University, the Netherlands., Khatri BS; The Francis Crick Institute, London, UK; Department of Life Sciences, Imperial College London, London, UK., Krug J; Institute for Biological Physics, University of Cologne, Köln, Germany., Louis AA; Rudolf Peierls Centre for Theoretical Physics, University of Oxford, Oxford, UK., Martin NS; Theory of Condensed Matter Group, Cavendish Laboratory, University of Cambridge, Cambridge, UK; Sainsbury Laboratory, University of Cambridge, Cambridge, UK., Payne JL; Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Tarnowski MJ; School of Biological Sciences, University of Bristol, Bristol, UK., Weiß M; Theory of Condensed Matter Group, Cavendish Laboratory, University of Cambridge, Cambridge, UK; Sainsbury Laboratory, University of Cambridge, Cambridge, UK.

Publikováno v: Physics of life reviews [Phys Life Rev] 2022 Sep; Vol. 42, pp. 19-24. Date of Electronic Publication: 2022 May 23.

Modular decomposition of protein structure using community detection

Autor: Grant, WP, Ahnert, SE, Estrada, E

As the number of solved protein structures increases, the opportunities for meta-analysis of this dataset increase too. Protein structures are known to be formed of domains; structural and functional subunits that are often repeated across sets of pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822977c4a6ae8af05a10f0ad9f1b1e8d
https://www.repository.cam.ac.uk/handle/1810/292541