Zobrazeno 1 - 10
of 1 359
pro vyhledávání: '"Ahnert P"'
This paper proposes temporally aligned Large Language Models (LLMs) as a tool for longitudinal analysis of social media data. We fine-tune Temporal Adapters for Llama 3 8B on full timelines from a panel of British Twitter users, and extract longitudi
Externí odkaz:
http://arxiv.org/abs/2409.17990
Pairwise comparisons based on human judgements are an effective method for determining rankings of items or individuals. However, as human biases perpetuate from pairwise comparisons to recovered rankings, they affect algorithmic decision making. In
Externí odkaz:
http://arxiv.org/abs/2408.13034
Autor:
Yin, Guoli, Bai, Haoping, Ma, Shuang, Nan, Feng, Sun, Yanchao, Xu, Zhaoyang, Ma, Shen, Lu, Jiarui, Kong, Xiang, Zhang, Aonan, Yap, Dian Ang, zhang, Yizhe, Ahnert, Karsten, Kamath, Vik, Berglund, Mathias, Walsh, Dominic, Gindele, Tobias, Wiest, Juergen, Lai, Zhengfeng, Wang, Xiaoming, Shan, Jiulong, Cao, Meng, Pang, Ruoming, Wang, Zirui
Recent advances in large language models (LLMs) have increased the demand for comprehensive benchmarks to evaluate their capabilities as human-like agents. Existing benchmarks, while useful, often focus on specific application scenarios, emphasizing
Externí odkaz:
http://arxiv.org/abs/2407.18961
Autor:
Wei Li, James Welsh, Vivek Verma, David S Hong, Nathan I Comeaux, Joe Y Chang, Jordi Rodon Ahnert, Daniel D Karp, Ecaterina E Dumbrava, Xinyan Xu, Girish S Shroff, Aileen Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 10 (2024)
Background BMS-986156 is an agonist of the glucocorticoid-induced tumor necrosis factor receptor (TNFR)-related protein (GITR) and promotes increased effector T-cell activation. Combined anti-GITR, anti-programmed death-1, anti-cytotoxic T-lymphocyte
Externí odkaz:
https://doaj.org/article/410ba5e120724ccebba6aa124b66d32f
Autor:
Wei He, Weiyi Peng, Si Chen, Jordi Rodon Ahnert, Jiakai Hou, Leilei Shi, Ritu Bohat, Yue Lu, Han Xu, Sana Sharif, Roshni Jaffery, Ashley Guerrero, Rongjie Fu, Ningbo Zheng, Nicholas A Egan, Chengtai Yu, Shuyue Wang, Donjeta Gjuka, Everett M Stone, Pooja Anil Shah, Taiping Chen, Xinli Liu, Mark T Bedford
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 9 (2024)
Background Hyperactivated protein arginine methyltransferases (PRMTs) are implicated in human cancers. Inhibiting tumor intrinsic PRMT5 was reported to potentiate antitumor immune responses, highlighting the possibility of combining PRMT5 inhibitors
Externí odkaz:
https://doaj.org/article/f2ce79b83742456784a1825a87418410
Autor:
Carol J. Nowlen, Molly Daniels, Burak Uzunparmak, Ecaterina E. Ileana Dumbrava, Ying Yuan, Keyur P. Patel, Nadine Rayes, Jacqueline Harkenrider, Chetna Wathoo, Jennifer Veazie, Krystle A. Luna, Wanlin Wang, Chacha Horombe, Milind Javle, Jordi Rodon Ahnert, Timothy A. Yap, Banu Arun, Karen H. Lu, Funda Meric-Bernstam
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 7, Iss 1, Pp 7-17 (2024)
Introduction Genomic profiling is performed in patients with advanced or metastatic cancer, in order to direct cancer treatment, often sequencing tumor-only, without a matched germline comparator. However, because many of the genes analyzed on tumor
Externí odkaz:
https://doaj.org/article/1c82c80e6fbe4a119579d33a7fda0372
The quantification of visual aesthetics and complexity have a long history, the latter previously operationalized via the application of compression algorithms. Here we generalize and extend the compression approach beyond simple complexity measures
Externí odkaz:
http://arxiv.org/abs/2205.10271
Autor:
Heather Lin, Vivek Subbiah, Siqing Fu, Aung Naing, Courtney Nicholas, Shubham Pant, Chad Tang, Michael A Curran, David S Hong, Ying Yuan, Sarina A Piha-Paul, Jordi Rodon Ahnert, Timonthy A Yap, Apostolia M Tsimberidou, Daniel D Karp, Anupallavi Srinivasamani, Coline Couillault, Genevieve P Hartley, James Dai, Ecaterina E Ileana Dumbrava, Paola Guerrero, Sarah Dhebat, Theresa Proia
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective To evaluate signal transducer and activator of transcription 3 (STAT3) inhibition we conducted a co-clinical trial testing danvatirsen, a STAT3 antisense oligonucleotide (ASO) and checkpoint inhibition in conjunction with preclinical experi
Externí odkaz:
https://doaj.org/article/fd1c2105b438497dab4139b2a44f11d7
Autor:
Martha Schutzmeier, Lilly Sophia Brandstetter, Stephanie Stangl, Jutta Ahnert, Anna Grau, Laura Gerken, Hanna Klingshirn, Bernd Reuschenbach, Tobias Skazel, Maximilian Kippnich, Thomas Wurmb, Peter Heuschmann, Kirsten Haas
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background The number of patients depending on home mechanical ventilation (HMV) has increased substantially in Germany in recent years. These patients receive long-term care in different nursing facilities (nursing home, shared living commu
Externí odkaz:
https://doaj.org/article/91a333d202234ae3a9e87d2df3336bb0
Autor:
Turcin Saridogan, Argun Akcakanat, Ming Zhao, Kurt W. Evans, Erkan Yuca, Stephen Scott, Bryce P. Kirby, Xiaofeng Zheng, Min Jin Ha, Huiqin Chen, Patrick K. S. Ng, Timothy P. DiPeri, Gordon B. Mills, Jordi Rodon Ahnert, Senthil Damodaran, Funda Meric-Bernstam
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Several alterations in fibroblast growth factor receptor (FGFR) genes have been found in breast cancer; however, they have not been well characterized as therapeutic targets. Futibatinib (TAS-120; Taiho) is a novel, selective, pan-FGFR inhib
Externí odkaz:
https://doaj.org/article/54d8ba5ed19745f68237d1d74ca99a08