Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ahmet Bugra Aksel"'
Autor:
Mahmut Gozelle, Selen Gozde Kaya, Ahmet Bugra Aksel, Erva Ozkan, Filiz Bakar-Ates, Yesim Ozkan, Gokcen Eren
Publikováno v:
Bioorganic chemistry. 123
Sirtuin 2 (SIRT2), member of sirtuin family, belongs to class III histone deacetylases (HDACs) and is majorly cytosolic with occasional nuclear translocation. The enzymatic activity of SIRT2 is dependent on nicotinamide adenine dinucleotide (NAD+) an
Autor:
Filiz Bakar-Ates, Ahmet Bugra Aksel, Gokcen Eren, Semih Yagci, Yasemin Dündar, Mahmut Gozelle, Selen Gozde Kaya, Yeşim Özkan
Publikováno v:
Bioorganicmedicinal chemistry. 30
Sirtuins (SIRTs) are a class of nicotinamide adenine dinucleotide (NAD+)-dependent protein histone deacetylases (HDACs) that are evolutionarily conserved from bacteria to mammals. This group of enzymes catalyses the reversible deacetylation of lysine
Autor:
Hasan Erdinç Sellitepe, Jong Min Oh, İnci Selin Doğan, Sercan Yildirim, Ahmet Buğra Aksel, Geum Seok Jeong, Ahmed Khames, Mohamed A. Abdelgawad, Nicola Gambacorta, Orazio Nicolotti, Bijo Mathew, Hoon Kim
Publikováno v:
Applied Sciences, Vol 11, Iss 13, p 5830 (2021)
Nineteen tosylated acyl hydrazone derivatives were synthesized, and their inhibitory activities against monoamine oxidases (MAOs), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-secretase (BACE-1) were evaluated. Compound 3o was th
Externí odkaz:
https://doaj.org/article/eb8cfd8512cf41e4948ea3fa535f815d