Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ahmed Z El-Hashim"'
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0233938 (2020)
BackgroundOnion is one of the most commonly used plants in the traditional medicine for the treatment of various diseases. We recently demonstrated the anti-inflammatory properties of onion bulb extract (OBE) in reducing colitis severity in mice when
Externí odkaz:
https://doaj.org/article/90bafa5e77794512a059af8e56f6b70c
Autor:
Ahmed Z El-Hashim, Maitham A Khajah, Rhema S Babyson, Waleed M Renno, Charles I Ezeamuzie, Ibrahim F Benter, Saghir Akhtar
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224163 (2019)
The angiotensin-(1-7) [Ang-(1-7)]/MAS1 receptor signaling axis is a key endogenous anti-inflammatory signaling pathway. However, the mechanisms by which its mediates the anti-inflammatory effects are not completely understood. Using an allergic murin
Externí odkaz:
https://doaj.org/article/05fff90a4022440da81a901e0995fc3f
Autor:
Ahmed Z. El-Hashim, Maitham A. Khajah, Khaled Y. Orabi, Sowmya Balakrishnan, Hanan G. Sary, Ahmad M. Barakat
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 326-340 (2024)
AbstractContext Asthma presents a global health challenge. The main pharmacotherapy is synthetic chemicals and biological-based drugs that are costly, and have significant side effects. In contrast, use of natural products, such as onion (Allium cepa
Externí odkaz:
https://doaj.org/article/127ebbf353dd4b99ab74eeee4f30d609
Autor:
Saghir Akhtar, Bashayer Al-Zaid, Ahmed Z El-Hashim, Bindu Chandrasekhar, Sreeja Attur, Mariam H M Yousif, Ibrahim F Benter
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132215 (2015)
Cationic polyamidoamine (PAMAM) dendrimers are branch-like spherical polymers being investigated for a variety of applications in nanomedicine including nucleic acid drug delivery. Emerging evidence suggests they exhibit intrinsic biological and toxi
Externí odkaz:
https://doaj.org/article/b91dbb0d9ccc45409a029ce0092c54a9
Autor:
Fajer Al-Shamlan, Ahmed Z. El-Hashim
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background Inhaled bradykinin (BK) has been reported to both sensitize and induce cough but whether BK can centrally sensitize the cough reflex is not fully established. In this study, using a conscious guinea-pig model of cough, we investig
Externí odkaz:
https://doaj.org/article/b139d816d76549039f69b9ba0741fa98
Autor:
Ahmed Z. El-Hashim, Maitham A. Khajah, Khaled Y. Orabi, Sowmya Balakrishnan, Hanan G. Sary, Ala A. Abdelali
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The treatment of allergic diseases, such as asthma, with both conventional and novel therapies presents a challenge both in terms of optimal effect and cost. On the other hand, traditional therapies utilizing natural products such as onion have been
Externí odkaz:
https://doaj.org/article/6e40535c1a43445d8e56879ec3cdeb53
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Despite significant advances, asthma remains a cause of premature death, and current treatments are suboptimal. Antigen-specific Th2 cells and their cytokines are primary mediators of the pathophysiological changes seen in asthma. Studies in animal m
Externí odkaz:
https://doaj.org/article/3df940208da94a5091e56522ee41f696
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-17 (2021)
Respiratory Research
Respiratory Research
Background Cough hypersensitivity is a major characteristic feature associated with several types of cough, including chronic cough, but its underlying mechanisms remain to be fully understood. Inflammatory mediators, such as prostaglandin E2 (PGE2),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdcda86a26645de43f0769b607228107
https://doi.org/10.1186/s12931-021-01889-4
https://doi.org/10.1186/s12931-021-01889-4
Autor:
Ahmed Z. El-Hashim, Fajer Al-Shamlan
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-15 (2019)
Background Inhaled bradykinin (BK) has been reported to both sensitize and induce cough but whether BK can centrally sensitize the cough reflex is not fully established. In this study, using a conscious guinea-pig model of cough, we investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c6d5c84ff186e21de8afd791a70ce1
http://link.springer.com/article/10.1186/s12931-019-1060-8
http://link.springer.com/article/10.1186/s12931-019-1060-8
Publikováno v:
Journal of Diabetes Research, Vol 2014 (2014)
Angiotensin-(1-7) [Ang-(1-7)] may have beneficial effects in diabetes mellitus-induced erectile dysfunction (DMIED) but its molecular actions in the diabetic corpus cavernosum (CC) are not known. We characterized the effects of diabetes and/or chroni
Externí odkaz:
https://doaj.org/article/013eab296e8f48acba85fcb42839e79f