Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ahmed Uosef"'
Autor:
Mahmoud M. Gabr, Sawsan M. El-Halawani, Ayman F. Refaie, Sherry M. Khater, Amani M. Ismail, Mary S. Karras, Raghda W. Magar, Shorouk El Sayed, Malgorzata Kloc, Ahmed Uosef, Omaima M. Sabek, Mohamed A. Ghoneim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract This study was to determine whether extracellular vesicles (EVs) derived from insulin-producing cells (IPCs) can modulate naïve mesenchymal stromal cells (MSCs) to become insulin-secreting. MSCs were isolated from human adipose tissue. The
Externí odkaz:
https://doaj.org/article/c763a3cff9ee422abf116a22f6795d92
Autor:
Xiufeng Chu, Xiang Xiao, Guangchuan Wang, Ahmed Uosef, Xiaohua Lou, Preston Arnold, Yixuan Wang, Gangcheng Kong, Mou Wen, Laurie J. Minze, Xian C. Li
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-12 (2023)
Abstract Gasdermin D (GSDMD) is a critical mediator of pyroptosis, which consists of a N-terminal pore-forming domain and a C-terminal autoinhibitory domain. Its cytolytic activity is sequestered by the intramolecular autoinhibitory mechanism. Upon c
Externí odkaz:
https://doaj.org/article/0befee6e2bb240158219dd8cff8536b5
Autor:
Ahmed Uosef, Arijita Subuddhi, Annie Lu, Henry V. Ubelaker, Christof Karmonik, Jarek Wosik, Rafik M. Ghobrial, Malgorzata Kloc
Publikováno v:
Journal of Magnetic Resonance Open, Vol 12, Iss , Pp 100085- (2022)
Gadolinium-based MRI contrast agent Dotarem is commonly used in the clinic. Free Gd3+ is very toxic. Because the crystallographic radius of Gd3+ and Ca2+ is very similar, Gd3+ can compete with Ca2+ in the regulations of cellular functions. Gadolinium
Externí odkaz:
https://doaj.org/article/132a4f1e0d9e46dfaadd38988576dc94
Autor:
Malgorzata Kloc, Ahmed Uosef, Arijita Subuddhi, Jacek Z. Kubiak, Rafal P. Piprek, Rafik M. Ghobrial
Publikováno v:
Biology, Vol 11, Iss 8, p 1121 (2022)
This review introduces the subject of senescence, aging, and the formation of senescent multinucleated giant cells. We define senescence and aging and describe how molecular and cellular senescence leads to organismal senescence. We review the latest
Externí odkaz:
https://doaj.org/article/33063bae3eae4de5b9c846ae14190341
Autor:
Priyanka Chanana, Ahmed Uosef, Nicole Vaughn, Martha Suarez-Villagran, Rafik M. Ghobrial, Malgorzata Kloc, Jarek Wosik
Publikováno v:
Cells, Vol 11, Iss 5, p 757 (2022)
Magnetic resonance imaging (MRI) is widely used in diagnostic medicine. MRI uses the static magnetic field to polarize nuclei spins, fast-switching magnetic field gradients to generate temporal and spatial resolution, and radiofrequency (RF) electrom
Externí odkaz:
https://doaj.org/article/bd31fa091042406ab78905f8448ab32f
Autor:
Malgorzata Kloc, Priyanka Chanana, Nicole Vaughn, Ahmed Uosef, Jacek Z. Kubiak, Rafik M. Ghobrial
Publikováno v:
Biology, Vol 10, Iss 4, p 304 (2021)
Actin is one of the most abundant proteins in eukaryotic cells. There are different pools of nuclear actin often undetectable by conventional staining and commercial antibodies used to identify cytoplasmic actin. With the development of more sophisti
Externí odkaz:
https://doaj.org/article/c05341b4565a496582cdefc5b647b1db
Publikováno v:
Biology, Vol 10, Iss 3, p 238 (2021)
Human placenta formation relies on the interaction between fused trophoblast cells of the embryo with uterine endometrium. The fusion between trophoblast cells, first into cytotrophoblast and then into syncytiotrophoblast, is facilitated by the fusog
Externí odkaz:
https://doaj.org/article/95d0f8ad56e54a059892788f1e899f23
Autor:
Malgorzata Kloc, Ahmed Uosef, Martha Villagran, Robert Zdanowski, Jacek Z. Kubiak, Jarek Wosik, Rafik M. Ghobrial
Publikováno v:
Biology, Vol 10, Iss 2, p 70 (2021)
The small GTPase RhoA, and its down-stream effector ROCK kinase, and the interacting Rac1 and mTORC2 pathways, are the principal regulators of the actin cytoskeleton and actin-related functions in all eukaryotic cells, including the immune cells. As
Externí odkaz:
https://doaj.org/article/9e4f66451af24b01b7bc1bb536bb08f2
Publikováno v:
Archives of Virology
Archives of Virology, 2022, 167 (3), pp.737-749. ⟨10.1007/s00705-022-05366-1⟩
Archives of Virology, 2022, 167 (3), pp.737-749. ⟨10.1007/s00705-022-05366-1⟩
International audience; The actin cytoskeleton and actin-dependent molecular and cellular events are responsible for the organization of eukaryotic cells and their functions. Viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-Co
Autor:
Arijita Subuddhi, Ahmed Uosef, Dawei Zou, Henry V. Ubelaker, Rafik M. Ghobrial, Malgorzata Kloc
Publikováno v:
International Immunopharmacology. 118:110017