Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ahmed S. Abuelyaman"'
Autor:
D. Redelman, C. A. Burner, Ahmed S. Abuelyaman, D. Hudig, J. C. Powers, G. C. J. Fernandez, D. L. Garner, D. W. Holcombe, D. D. Palencia, C.-M. Kam
Publikováno v:
Biology of Reproduction. 55:536-542
The activable proacrosin/acrosin levels in bovine sperm were examined using fluorescent staining and flow cytometry. The proportion of sperm with active acrosin were determined using the biotinylated isocoumarin serine protease inhibitor, Bi-Aca-Aca-
Autor:
R A Gault, G R Ewoldt, Chih-Min Kam, James C. Powers, Susan L. Woodard, N. J. Allison, Ahmed S. Abuelyaman, Dorothy Hudig, U. Winkler
Publikováno v:
Molecular Immunology. 33:615-623
Cytotoxic lymphocytes and natural killer cells are able to kill their target cells in minutes. The death of the target cell occurs after the release of cytoplasmic granules from the effector cell. These granules contain the pore-forming protein perfo
Autor:
Christopher J. Kloxin, Joel D. Oxman, Ahmed S. Abuelyaman, Hee-Young Park, Christopher N. Bowman
Publikováno v:
Macromolecules. 45(14)
To reduce shrinkage stress which arises during the polymerization of crosslinked polymers, allyl sulfide functional groups were incorporated into methacrylate polymerizations to determine their effect on stress relaxation via addition-fragmentation c
Autor:
Christopher J. Kloxin, Joel D. Oxman, Ahmed S. Abuelyaman, Christopher N. Bowman, Hee-Young Park
Publikováno v:
Dental materials : official publication of the Academy of Dental Materials. 28(11)
Objectives To produce a reduced stress dental restorative material while simultaneously maintaining excellent mechanical properties, we have incorporated an allyl sulfide functional group into norbornene–methacrylate comonomer resins. We hypothesiz
Publikováno v:
Bioconjugate Chemistry. 5:400-405
Three fluorescein- and one Texas Red-labeled derivatives of [1-(N-dipeptidylamino)alkyl]phosphonate diphenyl esters were synthesized and evaluated as inhibitors of serine proteases. The two fluorophores, FITC and TXR, were attached to the peptide pho
Autor:
Jeanie B. McMillin, Wayne J. Brouillette, Paul E. Wolkowicz, Ahmed S. Abuelyaman, Tracy L. Hutchison, Ashraf Saeed
Publikováno v:
The Journal of Organic Chemistry. 59:4297-4303
Carnitine (1, 3-hydroxy-4-trimethylammoniobutyrate) is essential as a donor and acceptor of acyl groups in cellular metabolism. The major solution conformation of carnitine about C3-C4 contains the gauche relationship between the trimethylammonium an
Publikováno v:
Bioconjugate Chemistry. 4:560-567
Eight new biotinylated, mechanism-based isocoumarin serine protease inhibitors have been designed and synthesized to detect, localize, and isolate serine proteases. Isocoumarins that contain a 4-chloro group, a biotinylated substituent at the 7-posit
Publikováno v:
Organic Preparations and Procedures International. 25:243-246
Publikováno v:
Archives of biochemistry and biophysics. 344(2)
Diphenyl 1-(N-peptidylamino)alkanephosphonate esters are highly reactive, specific, and aqueously stable irreversible inhibitors which can be used to probe the functions of many serine proteases, including the lymphocyte granzymes. We synthesized 16