Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ahmed S Abdelfattah"'
Publikováno v:
eLife, Vol 9 (2020)
Understanding how the brain encodes and processes information requires the recording of neural activity that underlies different behaviors. Recent efforts in fluorescent protein engineering have succeeded in developing powerful tools for visualizing
Externí odkaz:
https://doaj.org/article/640c0b46a278434f91312c2b1c0f9fa9
Autor:
Joshua S. Selfe, Teresa J. S. Steyn, Eran F. Shorer, Richard J. Burman, Kira M. Düsterwald, Ariel Z. Kraitzick, Ahmed S. Abdelfattah, Eric R. Schreiter, Sarah E. Newey, Colin J. Akerman, Joseph V. Raimondo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Ionic driving forces provide the net electromotive force for ion movement across receptors, channels, and transporters, and are a fundamental property of all cells. In the nervous system, fast synaptic inhibition is mediated by chloride perm
Externí odkaz:
https://doaj.org/article/c0646bb3d3a84e5dae514f6b764b6a3a
Publikováno v:
SVU-International Journal of Veterinary Sciences, Vol 5, Iss 4, Pp 165-173 (2022)
The goal of the current work was to determine the quality of male and female cattle and buffalo meat, as well as a trial for improving meat quality by feeding the experimental groups from cattle and buffalo for four months in rations containing 16.5%
Externí odkaz:
https://doaj.org/article/f9d256893f0a48eca5b227d220a500cc
Autor:
Ahmed S. Abdelfattah, Rosario Valenti, Jihong Zheng, Allan Wong, GENIE Project Team, Kaspar Podgorski, Minoru Koyama, Douglas S. Kim, Eric R. Schreiter
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Genetically encoded voltage indicators (GEVIs) allow visualisation of fast action potentials in neurons but most are bright at rest and dimmer during an action potential. Here, the authors engineer electrochromic FRET GEVIs with fast, bright and posi
Externí odkaz:
https://doaj.org/article/2ea2ff2c1bd44acdb9e04c2ab44cdf71
Autor:
Yi Shen, Hod Dana, Ahmed S. Abdelfattah, Ronak Patel, Jamien Shea, Rosana S. Molina, Bijal Rawal, Vladimir Rancic, Yu-Fen Chang, Lanshi Wu, Yingche Chen, Yong Qian, Matthew D. Wiens, Nathan Hambleton, Klaus Ballanyi, Thomas E. Hughes, Mikhail Drobizhev, Douglas S. Kim, Minoru Koyama, Eric R. Schreiter, Robert E. Campbell
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract Background Genetically encoded calcium ion (Ca2+) indicators (GECIs) are indispensable tools for measuring Ca2+ dynamics and neuronal activities in vitro and in vivo. Red fluorescent protein (RFP)-based GECIs have inherent advantages relativ
Externí odkaz:
https://doaj.org/article/3c5ac42d7c74448db49c6b0217b181a3
Autor:
Ahmed S. Abdelfattah, Jihong Zheng, Amrita Singh, Yi-Chieh Huang, Daniel Reep, Getahun Tsegaye, Arthur Tsang, Benjamin J. Arthur, Monika Rehorova, Carl V.L. Olson, Yichun Shuai, Lixia Zhang, Tian-Ming Fu, Daniel E. Milkie, Maria V. Moya, Timothy D. Weber, Andrew L. Lemire, Christopher A. Baker, Natalie Falco, Qinsi Zheng, Jonathan B. Grimm, Mighten C. Yip, Deepika Walpita, Martin Chase, Luke Campagnola, Gabe J. Murphy, Allan M. Wong, Craig R. Forest, Jerome Mertz, Michael N. Economo, Glenn C. Turner, Minoru Koyama, Bei-Jung Lin, Eric Betzig, Ondrej Novak, Luke D. Lavis, Karel Svoboda, Wyatt Korff, Tsai-Wen Chen, Eric R. Schreiter, Jeremy P. Hasseman, Ilya Kolb
Publikováno v:
Neuron. 111:1547-1563.e9
Autor:
Adam J. Berro, Natalie Falco, Luke D. Lavis, Hersh K. Bhargava, Benjamien Moeyaert, Mariam Chupanova, Eric R. Schreiter, Claire Deo, Ahmed S. Abdelfattah, Helen Farrants
Publikováno v:
Nature Chemical Biology. 17:718-723
Functional imaging using fluorescent indicators has revolutionized biology, but additional sensor scaffolds are needed to access properties such as bright, far-red emission. Here, we introduce a new platform for 'chemigenetic' fluorescent indicators,
Autor:
Yi Shen, Hod Dana, Ahmed S. Abdelfattah, Ronak Patel, Jamien Shea, Rosana S. Molina, Bijal Rawal, Vladimir Rancic, Yu-Fen Chang, Lanshi Wu, Yingche Chen, Yong Qian, Matthew D. Wiens, Nathan Hambleton, Klaus Ballanyi, Thomas E. Hughes, Mikhail Drobizhev, Douglas S. Kim, Minoru Koyama, Eric R. Schreiter, Robert E. Campbell
Publikováno v:
BMC Biology, Vol 17, Iss 1, Pp 1-1 (2019)
In the online version of the article [1], Figure S1 was mistakenly replaced with Figure 1.
Externí odkaz:
https://doaj.org/article/8a51b70fc45946e783b7205986ef83e2
Autor:
Huang Y, Forest Cr, Mertz J, Luke D. Lavis, Michael N. Economo, Karel Svoboda, Natalie Falco, Ilya Kolb, Tsang A, Chen T, Weber Td, Chase M, Olson Cv, Shuai Y, Eric R. Schreiter, Jonathan B. Grimm, Ahmed S. Abdelfattah, Zheng Q, Deepika Walpita, Ondrej Novak, Andrew L. Lemire, Jeremy P. Hasseman, Minoru Koyama, Rehorova M, Gabe J. Murphy, Glenn C. Turner, Wong Am, Luke Campagnola, Zheng J, Lin B, Baker Ca, Moya Mv, Wyatt Korff, Ben J. Arthur, Reep D, Getahun Tsegaye, Yip Mc
The ability to optically image cellular transmembrane voltage at millisecond-timescale resolution can offer unprecedented insight into the function of living brains in behaving animals. The chemigenetic voltage indicator Voltron is bright and photost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fac09d341a409f95ae272efdbe1070b0
https://doi.org/10.1101/2021.11.09.467909
https://doi.org/10.1101/2021.11.09.467909
Autor:
Liam Paninski, Eric R. Schreiter, Bei Jung Lin, Takashi Kawashima, Ahmed S. Abdelfattah, Tsai Wen Chen, Ondrej Novak, Misha B. Ahrens, Gabe J. Murphy, Jihong Zheng, Karel Svoboda, Stephanie C. Seeman, Minoru Koyama, Jonathan B. Grimm, Yi Chieh Huang, Luke Campagnola, Jianing Yu, Johannes Friedrich, Ronak Patel, Amrita Singh, Yichun Shuai, Glenn C. Turner, Luke D. Lavis, Hui Liu, Kaspar Podgorski, John J. Macklin, Brett D. Mensh, Zhe Liu
Publikováno v:
Science. 365:699-704
Visualizing neuronal activity in vivo Imaging the changes in fluorescence of voltage-sensitive reagents would enable monitoring of the activity of neurons in vivo. Abdelfattah et al. created such a voltage indicator by designing a protein that combin