Robust antiviral activity of commonly prescribed antidepressants against emerging coronaviruses: in vitro and in silico drug repurposing studies

Autor: Omnia Kutkat, Yassmin Moatasim, Ahmed A. Al‐Karmalawy, Hamada S. Abulkhair, Mokhtar R. Gomaa, Ahmed N. El-Taweel, Noura M. Abo Shama, Mohamed GabAllah, Dina B. Mahmoud, Ghazi Kayali, Mohamed A. Ali, Ahmed Kandeil, Ahmed Mostafa

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Abstract During the current coronavirus disease 2019 (COVID-19) pandemic, symptoms of depression are commonly documented among both symptomatic and asymptomatic quarantined COVID-19 patients. Despite that many of the FDA-approved drugs have been show

Externí odkaz: https://doaj.org/article/7ad4712b32c143a68671cd3701b1b9b5

Systematic, active surveillance for Middle East respiratory syndrome coronavirus in camels in Egypt

Autor: Mohamed A Ali, Mahmoud M Shehata, Mokhtar R Gomaa, Ahmed Kandeil, Rabeh El-Shesheny, Ahmed S Kayed, Ahmed N El-Taweel, Mohamed Atea, Nagla Hassan, Ola Bagato, Yassmin Moatasim, Sara H Mahmoud, Omnia Kutkat, Asmaa M Maatouq, Ahmed Osman, Pamela P McKenzie, Richard J Webby, Ghazi Kayali

Publikováno v: Emerging Microbes and Infections, Vol 6, Iss 1, Pp 1-7 (2017)

Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe human infections and dromedary camels are considered an intermediary host. The dynamics of natural infection in camels are not well understood. Through systematic surveillance in E

Externí odkaz: https://doaj.org/article/95f486af5eb54ffdb594d09f71481252

Impact of Individual Viral Gene Segments from Influenza A/H5N8 Virus on the Protective Efficacy of Inactivated Subtype-Specific Influenza Vaccine

Autor: Yassmin Moatasim, Ahmed Kandeil, Ahmed Mostafa, Omnia Kutkat, Mohamed El Sayes, Ahmed N. El Taweel, Maha AlKhazindar, Elsayed T. AbdElSalam, Rabeh El-Shesheny, Ghazi Kayali, Mohamed A. Ali

Publikováno v: Pathogens, Vol 10, Iss 3, p 368 (2021)

Since its emergence in 2014, the highly pathogenic avian influenza H5N8 virus has continuously and rapidly spread worldwide in the poultry sector resulting in huge economic losses. A typical inactivated H5N8 vaccine is prepared using the six internal

Externí odkaz: https://doaj.org/article/77247edef8084ec49d7ff4b25a6290bf

Anticoagulants as Potential SARS-CoV-2 M

Autor: Ayman, Abo Elmaaty, Wagdy M, Eldehna, Muhammad, Khattab, Omnia, Kutkat, Radwan, Alnajjar, Ahmed N, El-Taweel, Sara T, Al-Rashood, Mohammed A S, Abourehab, Faizah A, Binjubair, Mohamed A, Saleh, Amany, Belal, Ahmed A, Al-Karmalawy

Publikováno v: International journal of molecular sciences. 23(20)

In this article, 34 anticoagulant drugs were screened in silico against the main protease (M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::115c29270fe94d1a5a3bf436281ac883
https://pubmed.ncbi.nlm.nih.gov/36293094

Prediction of Gut Wall Integrity Loss in Viral Gastroenteritis by Non-Invasive Marker

Autor: Hala G. Elnady, Ahmed N. EL-Taweel, Maysa T. Saleh, Lobna S. Sherif, Iman Helwa, Inas R. El-Alameey, Haiam Abdel Raouf, Amal I. El Shafie, Mai M. Youssef

Publikováno v: Open Access Macedonian Journal of Medical Sciences
Open Access Macedonian Journal of Medical Sciences, Vol 3, Iss 1, Pp 37-45 (2015)
Open Access Macedonian Journal of Medical Sciences; Vol. 3 No. 1 (2015): Mar 15 (OAMJMS); 37-45
Open Access Macedonian Journal of Medical Sciences; Vol 3, No 1 (2015): Mar 15 (OAMJMS); 37-45

BACKGROUND: Intestinal fatty acid binding proteins (I-FABPs) are mainly expressed in the intestinal villi, which are the initial site of destruction in viral gastroenteritis.AIM: This study was designed to assess serum I-FABPs as a predictor of gut w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b386a6e7e753f523decdb39af4917e
https://pubmed.ncbi.nlm.nih.gov/27275194