Controlled microwave-assisted reactions: A facile synthesis of polyfunctionally substituted phthalazines as dual EGFR and PI3K inhibitors in CNS SNB-75 cell line.

Autor: Hassan Nazmy M; Biochemistry Department, Faculty of Pharmacy, Minia University, Minia 61519, Egypt. Electronic address: maiiada_nazmy@mu.edu.eg., Ahmed Mekheimer R; Chemistry Department, Faculty of Science, Minia University, Minia 61519, Egypt., Shoman ME; Medicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minia 61519, Egypt., Abo-Elsebaa M; Chemistry Department, Faculty of Science, Minia University, Minia 61519, Egypt., Abd-Elmonem M; Chemistry Department, Faculty of Science, Minia University, Minia 61519, Egypt., Usef Sadek K; Chemistry Department, Faculty of Science, Minia University, Minia 61519, Egypt.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2022 May; Vol. 122, pp. 105740. Date of Electronic Publication: 2022 Mar 12.