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of 3
pro vyhledávání: '"Ahmed Mansour Abdelaal"'
Autor:
Mahathi Venkataramani, Ahmed Mansour Abdelaal, Zhen Bian, Lei Shi, Yuan Liu, Courtney Culpepper, Hongwei Liang, Koby Kidder, Ke Zen
Publikováno v:
European Journal of Immunology. 48:532-542
Myeloid-derived suppressor cells (MDSCs) promote tumor growth through, in part, inhibiting T-cell immunity. However, mechanisms underlying MDSC expansion and guidance of MDSCs toward the tumor microenvironment remain unclear. Employing Percoll densit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72240dbded775119f9e624de6d2216fb
https://doi.org/10.1002/eji.201746976
https://doi.org/10.1002/eji.201746976
Autor:
Koby Kidder, Lanqiao Xiong, Ahmed Mansour Abdelaal, Hongwei Liang, Mahathi Venkataramani, Yuan Liu, Ke Zen, Courtney Culpepper, Zhen Bian, Lei Shi
Although previous reports suggest that tumor-induced myeloid-derived suppressor cells (MDSC) inhibit T cells by L-arginine depletion through arginase-1 activity, we herein show that arginase-1 is neither inherently expressed in MDSC nor required for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26026ec18211f6e252d76d6bf7419ca3
https://europepmc.org/articles/PMC5997508/
https://europepmc.org/articles/PMC5997508/
Publikováno v:
The Journal of Immunology. 198:154.13-154.13
Tumor-induced myeloid derived suppressive cells (MDSC) have been reported to inhibit T cell responses. In our study MDSC inhibit T cell proliferation through arginase-1 dependent manner. However, surprisingly we observe that freshly isolated MDSC fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f02b62dec884f35eb783f93679ece001
https://doi.org/10.4049/jimmunol.198.supp.154.13
https://doi.org/10.4049/jimmunol.198.supp.154.13