Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ahmed M. Mosallam"'
Autor:
Aboubakr H. Abdelmonsef, Mohamed El-Naggar, Amal O. A. Ibrahim, Asmaa S. Abdelgeliel, Ihsan A. Shehadi, Ahmed M. Mosallam, Ahmed Khodairy
Publikováno v:
Molecules, Vol 29, Iss 23, p 5529 (2024)
A series of new quinazolin-2,4-dione derivatives incorporating amide/eight-membered nitrogen-heterocycles 2a–c, in addition, acylthiourea/amide/dithiolan-4-one and/or phenylthiazolidin-4-one 3a–d and 4a–d. The starting compound 1 was prepared b
Externí odkaz:
https://doaj.org/article/355859d9d95d421485f448069181f35e
Autor:
Abdelfattah Hassan, Ahmed M. Mosallam, Amal O. A. Ibrahim, Mohamed Badr, Aboubakr H. Abdelmonsef
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Multitarget anticancer drugs are more superior than single target drugs regarding patient compliance, drug adverse effects, drug-drug interactions, drug resistance as well as pharmaceutical industry economics. Dysregulation of both VEGFR-2 a
Externí odkaz:
https://doaj.org/article/6abb4a43cd8f440d82dd88137dd27b46
Autor:
Abdelfattah Hassan, Fawzy A. F. Mubarak, Ihsan A. Shehadi, Ahmed M. Mosallam, Hussain Temairk, Mohamed Badr, Aboubakr H. Abdelmonsef
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
The dual c-Met/vascular endothelial growth factor receptor 2 (VEGFR-2) TK inhibition is a good strategy to overcome therapeutic resistance to small molecules VEGFR-2 inhibitors. In this study, we designed 3-substituted quinazoline-2,4(1H,3H)-dione de
Externí odkaz:
https://doaj.org/article/3768d35228f6460582feda1e7e03f2fd
Publikováno v:
Oriental Journal Of Chemistry. 28:1567-1578
Pyromellitic dianhydride 1 was used as starting compound for the synthesis of some new derivatives of condensed dipyrrole, dibenzoxazine, and dipyridazine. Thus, the diimide 2 was formed on fusion of 1 with urea, thiourea and/or thiosemicarbazide. Al