Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ahmed M. Hashad"'
Autor:
Mohammed A. El-Lakany, Nadia Haghbin, Naman Arora, Ahmed M. Hashad, Galina Yu. Mironova, Maria Sancho, Robert Gros, Donald G. Welsh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The arterial myogenic response to intraluminal pressure elicits constriction to maintain tissue perfusion. Smooth muscle [Ca2+] is a key determinant of constriction, tied to L-type (CaV1.2) Ca2+ channels. While important, other Ca2+ channels
Externí odkaz:
https://doaj.org/article/059a78f6dc1a4315ac83ae7dec12006a
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Working memory is a fundamental cognitive process for decision-making and is a hallmark impairment in a variety of neuropsychiatric and neurodegenerative diseases. Spatial working memory paradigms are a valuable tool to assess these processes in rode
Externí odkaz:
https://doaj.org/article/32d42d6d5d4145bc9fcce7df02b6f157
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Vascular T-type Ca2+ channels (CaV3.1 and CaV3.2) play a key role in arterial tone development. This study investigated whether this conductance is a regulatory target of angiotensin II (Ang II), a vasoactive peptide that circulates and whic
Externí odkaz:
https://doaj.org/article/303109c026ad425cb293f8870ac61ba9
Publikováno v:
Microcirculation (New York, N.Y. : 1994)REFERENCES. 29(3)
The myogenic response sets the foundation for blood flow control. Recent findings suggest a role for G protein-coupled receptors (GPCR) and signaling pathways tied to the generation of reactive oxygen species (ROS). In this regard, this study ascerta
Autor:
Mario Kassmann, Sean M. Wilson, Ahmed M. Hashad, Maik Gollasch, Jose L. Puglisi, Donald G. Welsh, Monica Romero, Osama F. Harraz, Suzanne E. Brett
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:2371-2381
Objective— This study examined whether caveolae position Ca V 3.2 (T-type Ca2+ channel encoded by the α-3.2 subunit) sufficiently close to RyR (ryanodine receptors) for extracellular Ca 2+ influx to trigger Ca 2+ sparks and large-conductance Ca 2+
Publikováno v:
The Journal of Physiology. 596:4863-4877
Key points In arterial smooth muscle, Ca2+ sparks are elementary Ca2+ -release events generated by ryanodine receptors (RyRs) to cause vasodilatation by opening maxi Ca2+ -sensitive K+ (BKCa ) channels. This study elucidated the contribution of T-typ
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
Vascular T-type Ca2+ channels (CaV3.1 and CaV3.2) play a key role in arterial tone development. This study investigated whether this conductance is a regulatory target of angiotensin II (Ang II), a vasoactive peptide that circulates and which is loca
Autor:
Ahmed M, Hashad, Osama F, Harraz, Suzanne E, Brett, Monica, Romero, Mario, Kassmann, Jose L, Puglisi, Sean M, Wilson, Maik, Gollasch, Donald G, Welsh
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 38(10)
Objective- This study examined whether caveolae position Ca
Autor:
Maria Sancho, Bjørn Olav Hald, Donald G. Welsh, Suzanne E. Brett, Sean P. Marrelli, Nina Samson, Ahmed M. Hashad
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 37:2171-2184
The conducted vasomotor response reflects electrical communication in the arterial wall and the distance signals spread is regulated by three factors including resident ion channels. This study defined the role of inward-rectifying K+channels (KIR) i
Publikováno v:
Signal Transduction and Smooth Muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec0b2f4c23e6673e41748193d9566e46
https://doi.org/10.1201/b20699-6
https://doi.org/10.1201/b20699-6