Výsledky vyhledávání - "Ahmed M. Debela"

Akademický článek

Surface Functionalization Strategies of Polystyrene for the Development Peptide-Based Toxin Recognition

Autor: Ahmed M. Debela, Catherine Gonzalez, Monica Pucci, Shemsia M. Hudie, Ingrid Bazin

Publikováno v: Sensors, Vol 22, Iss 23, p 9538 (2022)

The development of a robust surface functionalization method is indispensable in controlling the efficiency, sensitivity, and stability of a detection system. Polystyrene (PS) has been used as a support material in various biomedical fields. Here, we

Externí odkaz: https://doaj.org/article/04009bc608174e4d925daebb4cf37820

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Electrochemical primer extension based on polyoxometalate electroactive labels for multiplexed detection of single nucleotide polymorphisms

Autor: Serge Thorimbert, Bernold Hasenknopf, Ahmed M. Debela, Ciara K. O'Sullivan, Ioannis Katakis, Laura A. Uribe, Nassif Chahin, Mayreli Ortiz

Publikováno v: Biosensors and Bioelectronics
Biosensors and Bioelectronics, Elsevier, 2018, 117, pp.201-206. ⟨10.1016/j.bios.2018.06.014⟩

Polyoxymetalates (POMs) ([SiW 11 O 39 {Sn(CH 2 ) 2 CO)}] 4- and [P 2 W 17 O 61 {Sn(CH 2 ) 2 CO)}] 6- ) were used to modify dideoxynucleotides (ddNTPs) through amide bond formation, and applied to the multiplexed detection of single nucleotide polymor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4103ac28cba559b622fc817aeb2a5150
https://doi.org/10.1016/j.bios.2018.06.014

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PCR Incorporation of Polyoxometalate Modified Deoxynucleotide Triphosphates and Their Application in Molecular Electrochemical Sensing of Yersinia pestis

Autor: Mayreli Ortiz, Markéta Svobodová, Ciara K. O'Sullivan, Denis Lesage, Bernold Hasenknopf, Serge Thorimbert, Richard B. Cole, Ahmed M. Debela

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, 2017, 23 (44), pp.10597--10603. ⟨10.1002/chem.201701295⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2017, 23 (44), pp.10597--10603. ⟨10.1002/chem.201701295⟩

Redox-labeled nucleotides are of increasing interest for the fabrication of next generation molecular tools and should meet requirements of being thermally stable, sensitive, and compatible with polymerase-mediated incorporation while also being elec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0005534de69e7b5e67c8ba02be48f55c
https://doi.org/10.1002/chem.201701295

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Functionalized Deoxynucleotides and DNA Primers for Electrochemical Diagnostics of Disease Predispostions

Autor: Serge Thorimbert, Ciara K. O'Sullivan, Mayreli Ortiz, Valerio Beni, Denis Lesage, Bernold Hasenknopf, Richard B. Cole, Ahmed M. Debela

Publikováno v: ECS Transactions. 77:1873-1883

Redox labeled DNAs are of increasing interest for the fabrication of next generation molecular tools. In the present work we are investigating the use of various redox labeled dNTPs, ddNTPs and DNA ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd207621b98fd9b1c522e2f8ae2f8e2d
https://doi.org/10.1149/07711.1873ecst

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Stable Carboxylate-Terminated Gold Surfaces Produced by Spontaneous Grafting of an Alkyltin Compound

Autor: Christophe Méthivier, Bernold Hasenknopf, Mayreli Ortiz, Ciara K. O'Sullivan, Ahmed M. Debela, Serge Thorimbert

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2018, 24 (43), pp.11177-11184. ⟨10.1002/chem.201801854⟩

Self-assembled monolayers formed by chemisorption of thiolated molecules on gold surfaces are widely applied for biosensing. Moreover, and due to the low stability of thiol-gold chemistry, contributions to the functionalisation of gold substrates wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9069fb58be60d863697b6f9ec6bb84
https://hal.sorbonne-universite.fr/hal-01878679

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Surface functionalisation of carbon for low cost fabrication of highly stable electrochemical DNA sensors

Autor: Ahmed M. Debela, Mayreli Ortiz, Ciara K. O'Sullivan, Valerio Beni

Publikováno v: Biosensors & Bioelectronics
Repositori Institucional de la Universitat Rovira i Virgili
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An alternative strategy for surface tethering of DNA probes, where highly reactive glassy carbon (GC) substrates are prepared via electrochemical hydrogenation and electrochemical/chemical chlorination is reported. Thiolated DNA probes and alkanethio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f101e40e41a248bf1d1f45476d64ec8d
https://doi.org/10.1016/j.bios.2015.03.076

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Biofunctionalization of Polyoxometalates with DNA Primers, Their Use in the Polymerase Chain Reaction (PCR) and Electrochemical Detection of PCR Products

Autor: Mayreli Ortiz, Richard B. Cole, Ahmed M. Debela, Bernold Hasenknopf, Serge Thorimbert, Denis Lesage, Valerio Beni, Ciara K. O'Sullivan

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2015, 21 (49), pp.17721--17727. ⟨10.1002/chem.201502247⟩
Chemistry-A European Journal, 2015, 21 (49), pp.17721--17727. ⟨10.1002/chem.201502247⟩

The bioconjugation of polyoxometalates (POMs), which are inorganic metal oxido clusters, to DNA strands to obtain functional labeled DNA primers and their potential use in electrochemical detection have been investigated. Activated monooxoacylated po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4baf8d22eb4195a17cb99a3e32154e
https://hal.archives-ouvertes.fr/hal-01624684

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Electrochemical genosensor based on three-dimensional DNA polymer brushes monolayers

Autor: Olivier Y.F. Henry, Ahmed M. Debela, Sinead Kirwan, Ciara K. O'Sullivan

Publikováno v: Electrochemistry Communications, Vol 13, Iss 11, Pp 1155-1158 (2011)
Electrochemistry Communications

A new approach to the three dimensional integration of short DNA strands at gold electrode surfaces via the in situ formation of DNA-acrylamide conjugates is presented. Surface initiated atom transfer radical polymerisation was employed to grow acryl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7841111cb7cc692029ebb7bab34e9c30
http://www.sciencedirect.com/science/article/pii/S1388248111003869

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