Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Ahmed M Al-Abd"'
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0168938 (2017)
P-glycoprotein (Pgp) is a membrane bound efflux pump spread in a variety of tumor cells and considered as a main component of multidrug resistance (MDR) to chemotherapies. In this work, three groups of compounds (imidazolone, oxazolone and vinyl dipe
Externí odkaz:
https://doaj.org/article/c8ddc7c7bcc24c9b8794beea285517d7
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98559 (2014)
Chemical investigation of Sophora japonica seeds resulted in the isolation of seven metabolites identified as: genistin (1), sophoricoside (2), sophorabioside (3), sophoraflavonoloside (4), genistein 7,4'-di-O-β-D-glucopyransoide (5), kaempferol 3-O
Externí odkaz:
https://doaj.org/article/050b70e72c574efe9d5ffb2a340a0f6a
Autor:
Ahmed M Al-Abd, Fahad A Al-Abbasi, Salwa M Nofal, Amani E Khalifa, Richard O Williams, Wafaa I El-Eraky, Ayman A Nagy, Ashraf B Abdel-Naim
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111843 (2014)
Nimesulide is a COX-2 inhibitor used for symptomatic relief of rheumatoid arthritis. Leflunomide is an anti-pyrimidine used to manage the progression of rheumatoid arthritis. Herein we studied the influence of nimesulide and leflunomide combination i
Externí odkaz:
https://doaj.org/article/ecc06342edc84ef387dff8d272ee6b3c
Autor:
Mostafa A El-Sayed, Ali A Shabaka, Osama A El-Shabrawy, Nemat A Yassin, Sawsan S Mahmoud, Siham M El-Shenawy, Emad Al-Ashqar, Wael H Eisa, Niveen M Farag, Marwa A El-Shaer, Nabila Salah, Ahmed M Al-Abd
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76207 (2013)
Gold nanorods (GNR) within tumor microregions are characterized by their ability to absorb near IR light and emit heat in what is called photoplasmonic effect. Yet, the efficacy of nanoparticles is limited due to intratumoral tissue distribution reas
Externí odkaz:
https://doaj.org/article/9209b488bf854c91ab8002a69ce81146
Publikováno v:
ACS Omega, Vol 8, Iss 20, Pp 18299-18305 (2023)
Externí odkaz:
https://doaj.org/article/36a800cdf2bc4f6f9f46e238fa3c0e77
Autor:
Ola E. Abdel-Sattar, Rasha Mosa Allam, Ahmed M. Al-Abd, Bharathi Avula, Kumar Katragunta, Ikhlas A. Khan, Ahmed M. El-Desoky, Shanaz O. Mohamed, Ali El-Halawany, Essam Abdel-Sattar, Meselhy R. Meselhy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract The members of the genus Phyllanthus have long been used in the treatment of a broad spectrum of diseases. They exhibited antiproliferative activity against various human cancer cell lines. Breast cancer is the most diagnosed cancer and a le
Externí odkaz:
https://doaj.org/article/e338bddf83164027b7e4ac73f50e5af7
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 6, Pp 754-762 (2020)
In contrast to plasma pharmacokinetics, intratumoral pharmacokinetics of doxorubicin (DOX) determines its spatial anti-tumoral activity. Three-dimensional multicellular layers (MCL) model for solid tumors present optimum experimental platform for stu
Externí odkaz:
https://doaj.org/article/e2e8ffba75954be7a9aa62d47a3a050e
Autor:
Reham K. Abuhijjleh, Samiullah Shabbir, Ahmed M. Al-Abd, Nada H. Jiaan, Shahad Alshamil, Eman M. El-labbad, Sherief I. Khalifa
Publikováno v:
PeerJ, Vol 9, p e11778 (2021)
Marine life has provided mankind with unique and extraordinary chemical structures and scaffolds with potent biological activities. Many organisms and secondary metabolites derived from fungi and symbionts are found to be more environmentally friendl
Externí odkaz:
https://doaj.org/article/9d19687decc4449ca11dcf17184c45e5
Autor:
Mahmoud Zaki El-Readi, Ahmed M. Al-Abd, Mohammad A. Althubiti, Riyad A. Almaimani, Hiba Saeed Al-Amoodi, Mohamed Lotfy Ashour, Michael Wink, Safaa Yehia Eid
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Plant secondary metabolites (SMs) common natural occurrences and the significantly lower toxicities of many SM have led to the approaching development and use of these compounds as effective pharmaceutical agents; especially in cancer therapy. A comb
Externí odkaz:
https://doaj.org/article/3b9db436c096471ab18ffd2330c61cdf
Autor:
Hanan A. Bashmail, Aliaa A. Alamoudi, Abdulwahab Noorwali, Gehan A. Hegazy, Ghada AJabnoor, Hani Choudhry, Ahmed M. Al-Abd
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract The use of anti-cancer adjuvant therapy is rationalized by potentiating the efficacy, and/or protecting from major side effects of chemotherapeutics. Thymoquinone (TQ) is a naturally occurring compound with cumulative evidence of anti-cancer
Externí odkaz:
https://doaj.org/article/fead3b6d3df847a8819eb57af7c0ae38