Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ahmed H. Al-Amri"'
A Recessively Inherited Risk Locus on Chromosome 13q22-31 Conferring Susceptibility to Schizophrenia
Autor:
Nancy Kiwan, Peter W.R. Woodruff, Colin A. Johnson, Anneka Tomlinson, Steven J. Clapcote, Hassen Al-Amin, Iain D. Wilkinson, Sophia Ahmed, Joanna C. Neill, Jamshid Nazari, Ahmed H Al-Amri, Chris F. Inglehearn, Rifka S Chamali, Manir Ali, Tariq Mahmood, Mohammed E El-Asrag, Juliette Randerson Moor, Suhaila Ghuloum, Shabana Khan, Alastair G. Cardno, Hamid A. Alhaj, James A. Poulter
Publikováno v:
Schizophrenia Bulletin
We report a consanguineous family in which schizophrenia segregates in a manner consistent with recessive inheritance of a rare, partial-penetrance susceptibility allele. From 4 marriages between 2 sets of siblings who are half first cousins, 6 offsp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd63b2e3dc9d25cbc8977f0f37b9713
https://doi.org/10.1093/schbul/sbaa161
https://doi.org/10.1093/schbul/sbaa161
Autor:
Ahmed H. Al-Amri, Paul Armstrong, Mascia Amici, Clemence Ligneul, James Rouse, Mohammed E. El-Asrag, Andreea Pantiru, Valerie E. Vancollie, Hannah W.Y. Ng, Jennifer A. Ogbeta, Kirstie Goodchild, Jacob Ellegood, Christopher J. Lelliott, Jonathan G.L. Mullins, Amanda Bretman, Ruslan Al-Ali, Christian Beetz, Lihadh Al-Gazali, Aisha Al Shamsi, Jason P. Lerch, Jack R. Mellor, Abeer Al Sayegh, Manir Ali, Chris F. Inglehearn, Steven J. Clapcote
Publikováno v:
Al-Amri, A H, Armstrong, P, Amici, M, Ligneul, C, Mellor, J R & Clapcote, S J 2022, ' PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice and Fruit Flies ', Biological Psychiatry, vol. 92, no. 4, pp. 323-334 . https://doi.org/10.1016/j.biopsych.2021.12.017
BackgroundThe discovery of coding variants in genes that confer risk of intellectual disability (ID) is an important step toward understanding the pathophysiology of this common developmental disability.MethodsHomozygosity mapping, whole-exome sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c438ba4555785a1f1213cff239036c
https://cronfa.swan.ac.uk/Record/cronfa59175/Download/59175__23886__9c4736e50fd24c30adbf62bd8435ff6d.pdf
https://cronfa.swan.ac.uk/Record/cronfa59175/Download/59175__23886__9c4736e50fd24c30adbf62bd8435ff6d.pdf
Autor:
Manir Ali, Khalsa Al Lamki, Mohammed E El-Asrag, Ahlam Gabr, Chris F. Inglehearn, Mazin Al Khabouri, Mohammed Al-Kindi, Ahmed H Al-Amri, Ahmed B. Idris, Nadia Al Wardy, Steven J. Clapcote, Abeer Al Saegh, Watfa Al-Mamari
Publikováno v:
European journal of medical genetics. 62(12)
Hearing loss is a debilitating disorder that impairs language acquisition, resulting in disability in children and potential isolation in adulthood. Its onset can have a genetic basis, though environmental factors, which are often preventable, can al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f162b13f80e6eac18616be060135d4
https://pubmed.ncbi.nlm.nih.gov/30476627
https://pubmed.ncbi.nlm.nih.gov/30476627
Autor:
Steven J. Clapcote, Ahmed H Al-Amri, Amanda Bretman, Manir Ali, James Rouse, Chris F. Inglehearn, Thomas Wainwright, Paul Armstrong
Publikováno v:
IBRO Reports. 6:S94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06a65f994418069b755732c71bc9f622
https://doi.org/10.1016/j.ibror.2019.07.306
https://doi.org/10.1016/j.ibror.2019.07.306
Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition
Autor:
Fang Liu, Tatiana V. Lipina, John Georgiou, Dongxu Zhai, Steven J. Clapcote, Enoch Ng, John C. Roder, Christina Elliott, Ryan T. Cameron, Jonathan G. L. Mullins, George S. Baillie, Ahmed H Al-Amri, Ho Suk Mun, Alexander McGirr
Publikováno v:
Neuropsychopharmacology
Cognitive dysfunction is a core feature of dementia and a prominent feature in psychiatric disease. As non-redundant regulators of intracellular cAMP gradients, phosphodiesterases (PDE) mediate fundamental aspects of brain function relevant to learni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb58c94b2fdfa3fff18a39e19fe6a153
Autor:
Steven J. Clapcote, Chris F. Inglehearn, Watfa Al-Mamari, Ahmed H Al-Amri, Manir Ali, Jose Luis Ivorra, Mohammed E El-Asrag, Abeer Al Saegh, Alastair G. Cardno
Publikováno v:
American journal of medical genetics. Part A. 170(7)
Intellectual disability (ID) is the term used to describe a diverse group of neurological conditions with congenital or juvenile onset, characterized by an IQ score of less than 70 and difficulties associated with limitations in cognitive function an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85036d3379a12540712a647b6d160932
https://pubmed.ncbi.nlm.nih.gov/27148795
https://pubmed.ncbi.nlm.nih.gov/27148795
Autor:
Alexander McGirr, Tatiana V Lipina, Ho-Suk Mun, John Georgiou, Ahmed H Al-Amri, Enoch Ng, Dongxu Zhai, Christina Elliott, Ryan T Cameron, Jonathan GL Mullins, Fang Liu, George S Baillie, Steven J Clapcote, John C Roder
Publikováno v:
Neuropsychopharmacology. 42:1178-1178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b091c75adff7d2743a4d515dfc8234e
https://doi.org/10.1038/npp.2016.263
https://doi.org/10.1038/npp.2016.263