Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ahmed G K Habib"'
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190523 (2018)
Ring chromosomes are circular chromosomal abnormalities that have been reported in association with some genetic disorders and cancers. In Schizosaccharomyces pombe, lack of function of protection of telomere 1 (Pot1) or telomerase catalytic subunit
Externí odkaz:
https://doaj.org/article/48481e153a024a1fa00b1e58d36498f6
Autor:
Tomoko Nanbu, Luân C Nguyễn, Ahmed G K Habib, Naoya Hirata, Shinobu Ukimori, Daiki Tanaka, Kenta Masuda, Katsunori Takahashi, Masashi Yukawa, Eiko Tsuchiya, Masaru Ueno
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140456 (2015)
The uncapping of telomeres induces a DNA damage response. In Schizosaccharomyces pombe, deletion of pot1+ causes telomere uncapping and rapid telomere resection, resulting in chromosome fusion. Using the nmt-pot1-aid strain, we previously reported th
Externí odkaz:
https://doaj.org/article/4bcc363bd672429c834725231787d1f1
Autor:
Hamada Hashem, Abdelfattah Hassan, Walid M. Abdelmagid, Ahmed G. K. Habib, Mohamed A. A. Abdel-Aal, Ali M. Elshamsy, Amr El Zawily, Ibrahim Taha Radwan, Stefan Bräse, Ahmed S. Abdel-Samea, Safwat M. Rabea
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1154 (2024)
A series of novel thiazole-based chalcones were evaluated for their anticancer activity as potential tubulin polymerization inhibitors. In vitro anticancer screening for the thiazole derivatives 2a–2p exhibited broad-spectrum antitumor activity aga
Externí odkaz:
https://doaj.org/article/eec1b966579b4861baf1ea65339aadd4
Autor:
Amer Ali Abd El-Hafeez, Hala Mohamed M. Marzouk, Mohamed A. A. Abdelhamid, Hazim O. Khalifa, Tamer H. A. Hasanin, Ahmed G. K. Habib, Fatma Mahmoud Abdelwahed, Fatma M. Barakat, Eslam M. Bastawy, Eman M. B. Abdelghani, Toru Hosoi, Koichiro Ozawa, Ahmed M. Aref, Takashi Fujimura, Ahmed R. N. Ibrahim, Aalaa S. O. Abdelmoniem, Hagar Elghazawy, Pradipta Ghosh, Seiji Kawamoto, Seung Pil Pack
Publikováno v:
Biotechnology and Bioprocess Engineering. 27:833-845
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2872f9fa357efdeb493d33dd48b4ee1
https://doi.org/10.1007/s12257-022-0085-x
https://doi.org/10.1007/s12257-022-0085-x
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 86:224-230
Circular chromosomes have frequently been observed in tumors of mesenchymal origin. In the fission yeast Schizosaccharomyces pombe, deletion of pot1+ results in rapid telomere loss, and the resulting survivors have circular chromosomes. Fission yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ee3e8c9515810c2a84232c1fdcbc68
https://doi.org/10.1093/bbb/zbab215
https://doi.org/10.1093/bbb/zbab215
Autor:
Hamada H. H. Mohammed, Doaa Mohamed Elroby Ali, Mohamed Badr, Ahmed G. K. Habib, Abobakr Mohamed Mahmoud, Sarah M. Farhan, Shimaa Salah Hassan Abd El Gany, Soad A. Mohamad, Alaa M. Hayallah, Samar H. Abbas, Gamal El-Din A. Abuo-Rahma
Publikováno v:
Molecular Diversity.
Abstract A series of N-4 piperazinyl ciprofloxacin derivatives as urea-tethered ciprofloxacin-chalcone hybrids 2a-j and thioacetyl-linked ciprofloxacin-pyrimidine hybrids 5a-i were synthesized. The target compounds were investigated for their antibac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4660ec9a4ed0372d68115ec1fc7af6d5
https://doi.org/10.1007/s11030-022-10528-z
https://doi.org/10.1007/s11030-022-10528-z
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190523 (2018)
PLoS ONE
PLoS ONE
Ring chromosomes are circular chromosomal abnormalities that have been reported in association with some genetic disorders and cancers. In Schizosaccharomyces pombe, lack of function of protection of telomere 1 (Pot1) or telomerase catalytic subunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27947949a9ea79364d59c4631d12e35e
http://europepmc.org/articles/PMC5752009?pdf=render
http://europepmc.org/articles/PMC5752009?pdf=render
Publikováno v:
Biochemical and Biophysical Research Communications. 464:140-146
Protection of telomere (Pot1) is a single-stranded telomere binding protein which is essential for chromosome ends protection. Fission yeast Rqh1 is a member of RecQ helicases family which has essential roles in the maintenance of genomic stability a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822fc48ec4a7db694eb07bc7d400305e
https://doi.org/10.1016/j.bbrc.2015.06.098
https://doi.org/10.1016/j.bbrc.2015.06.098
Autor:
Taisuke Hiromoto, Ahmed Gomaa Gomaa Darwish, Akemi Nakano, Kenta Masuda, Masashi Yukawa, Eiko Tsuchiya, Ahmed G. K. Habib, Katsunori Takahashi, Yoshitake Matsumoto, Masaru Ueno
Publikováno v:
Molecular and Cellular Biology. 37
The spindle assembly checkpoint (SAC) monitors defects in kinetochore-microtubule attachment or lack of tension at kinetochores and arrests cells at prometaphase. In fission yeast, the double mutant between pot1Δ and the helicase-dead point mutant o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5b00a00368610a5c8a25d7d55bed3c
https://doi.org/10.1128/mcb.00175-17
https://doi.org/10.1128/mcb.00175-17
Autor:
Ahmed G. K. Habib, Yoshitake Matsumoto, Taisuke Hiromoto, Katsunori Takahashi, Akemi Nakano, Masaru Ueno, Masashi Yukawa, Eiko Tsuchiya, Kenta Masuda, Ahmed Gomaa Gomaa Darwish
Publikováno v:
Molecular and Cellular Biology. 34:1389-1397
The spindle assembly checkpoint (SAC) monitors defects in kinetochore-microtubule attachment or lack of tension at kinetochores and arrests cells at prometaphase. In fission yeast, the double mutant between pot1Δ and the helicase-dead point mutant o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5d7ff57322bd052526b1c9927a75965
https://doi.org/10.1128/mcb.01704-13
https://doi.org/10.1128/mcb.01704-13