Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Ahmed Elattar"'
Autor:
Dairui Dai, Janos Balega, Sudha Sundar, Sean Kehoe, Ahmed Elattar, Andrew Phillips, Kavita Singh
Publikováno v:
Journal of Investigative Surgery, Vol 35, Iss 2, Pp 426-431 (2022)
Objective To investigate the impact of serum albumin (at diagnosis and pre-operatively) on survival in patients undergoing cytoreductive surgery for advanced ovarian cancer(AOC) and whether improvement in albumin achieved following neoadjuvant chemot
Externí odkaz:
https://doaj.org/article/78525f3b7d7e430d94cad31b0fd4a1b6
Autor:
Andrew Bryant, Luke Vale, Dawn Craig, Raj Naik, Michael Grayling, Ketankumar Gajjar, Ahmed Elattar, Shaun Hiu, Eugenie Johnson
Publikováno v:
BMJ Open, Vol 12, Iss 8 (2022)
Objectives We consider expert opinion and its incorporation into a planned meta-analysis as a way of adjusting for anticipated publication bias. We conduct an elicitation exercise among eligible British Gynaecological Cancer Society (BGCS) members wi
Externí odkaz:
https://doaj.org/article/787a428e835a4921bc940b4a6addb2b4
Autor:
Rachel L O Donnell, Aiste McCormick, Asima Mukhopadhyay, Laura C Woodhouse, Madeleine Moat, Anna Grundy, Michelle Dixon, Angelika Kaufman, San Soohoo, Ahmed Elattar, Nicola J Curtin, Richard J Edmondson
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e90604 (2014)
The use of cell lines or animal models has significant disadvantages when dealing with a set of heterogeneous diseases such as epithelial ovarian cancer. This has clinical relevance in that biomarkers developed using cell line or animal models are of
Externí odkaz:
https://doaj.org/article/82cea6f499fa4cd4825288a9328efdfe
Autor:
Andrew Bryant, Eugenie Johnson, Michael Grayling, Shaun Hiu, Ahmed Elattar, Ketankumar Gajjar, Dawn Craig, Luke Vale, Raj Naik
Publikováno v:
American Journal of Therapeutics. 30:e36-e55
We present a systematic review and network meta-analysis (NMA) that is the precursor underpinning the Bayesian analyses that adjust for publication bias, presented in the same edition in AJT. The review assesses optimal cytoreduction for women underg
Autor:
Nicola J. Curtin, Richard J. Edmondson, Zdenek Hostomsky, Gerrit Los, Suzanne Kyle, Yvette Drew, Sarah J. Wilkinson, Aiste Cerbinskaite, Ahmed Elattar, Asima Mukhopadhyay
Supplementary Data from Development of a Functional Assay for Homologous Recombination Status in Primary Cultures of Epithelial Ovarian Tumor and Correlation with Sensitivity to Poly(ADP-Ribose) Polymerase Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616d01109e627d766ee3b9d2639ec530
https://doi.org/10.1158/1078-0432.22442429
https://doi.org/10.1158/1078-0432.22442429
Autor:
Nicola J. Curtin, Richard J. Edmondson, Zdenek Hostomsky, Gerrit Los, Suzanne Kyle, Yvette Drew, Sarah J. Wilkinson, Aiste Cerbinskaite, Ahmed Elattar, Asima Mukhopadhyay
Purpose: Poly(ADP-ribose) polymerase (PARP) inhibitors selectively target homologous recombination (HR)–defective cells and show good clinical activity in hereditary breast and ovarian cancer associated with BRCA1 or BRCA2 mutations. A high proport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe2fb860d2c38c8046117a59a78d30a
https://doi.org/10.1158/1078-0432.c.6519149.v1
https://doi.org/10.1158/1078-0432.c.6519149.v1
Autor:
Richard J. Edmondson, Nicola J. Curtin, Harriet Aneke, Perry Maxwell, W. Glenn McCluggage, Jennifer E. Quinn, Bisha Uzir, San Soohoo, Ahmed Elattar, Elizabeth R. Plummer, Asima Mukhopadhyay
PDF file - 103K, HR status and correlation with ex vivo cytotoxicity to PARP inhibitors. A, schema outlining study demontrating tight correlation between HR deficiency and sensitivity to PARP inhibitor for both epithelial EOCs and other HRD cancers b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fb380e34d55f26a47eca04577a5460
https://doi.org/10.1158/0008-5472.22391573
https://doi.org/10.1158/0008-5472.22391573
Autor:
Richard J. Edmondson, Nicola J. Curtin, Harriet Aneke, Perry Maxwell, W. Glenn McCluggage, Jennifer E. Quinn, Bisha Uzir, San Soohoo, Ahmed Elattar, Elizabeth R. Plummer, Asima Mukhopadhyay
Up to 50% of epithelial ovarian cancers (EOC) display defects in the homologous recombination (HR) pathway. We sought to determine the ramifications of the homologous recombination–deficient (HRD) status on the clinicopathologic features, chemother
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04db783e73165b5563cb457aa17bd202
https://doi.org/10.1158/0008-5472.c.6503291.v1
https://doi.org/10.1158/0008-5472.c.6503291.v1
Autor:
Richard J. Edmondson, Nicola J. Curtin, Harriet Aneke, Perry Maxwell, W. Glenn McCluggage, Jennifer E. Quinn, Bisha Uzir, San Soohoo, Ahmed Elattar, Elizabeth R. Plummer, Asima Mukhopadhyay
PDF file - 62K, RAD51 foci and ex vivo cytotocicity in HR competent and HR deficient primary cultures A. Box plot showing cytotoxicity to 10 muM rucaparib B. Box plot showing RAD51 foci formation after 24 hr exposure to rucaparib or hydroxyurea C. Sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68434986546ecbe424e4787eeaa638db
https://doi.org/10.1158/0008-5472.22391570.v1
https://doi.org/10.1158/0008-5472.22391570.v1
Autor:
Richard J. Edmondson, Nicola J. Curtin, Harriet Aneke, Perry Maxwell, W. Glenn McCluggage, Jennifer E. Quinn, Bisha Uzir, San Soohoo, Ahmed Elattar, Elizabeth R. Plummer, Asima Mukhopadhyay
PDF file - 70K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76eecaf355db4f716b755fd809dc43d4
https://doi.org/10.1158/0008-5472.22391567
https://doi.org/10.1158/0008-5472.22391567