Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ahmed El-Tahtawy"'
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 2, Iss 5, p e236 (2008)
BACKGROUND: A recent drug interaction study reported that when azithromycin was administered with the combination of ivermectin and albendazole, there were modest increases in ivermectin pharmacokinetic parameters. Data from this study were reanalyze
Externí odkaz:
https://doaj.org/article/2d29df77608f4d15bf3554edffc3633c
Autor:
Frank Jen, Bimal Malhotra, Marc R. Gastonguay, Kuan Gandelman, Ahmed El-Tahtawy, William Knebel
Publikováno v:
The Journal of Clinical Pharmacology. 53:505-516
The population pharmacokinetics (PPK) of atorvastatin and its principal active metabolite, o-hydroxyatorvastatin, were described in 6-17 years old pediatric hypercholesterolemia patients with a 2-compartment model for both parent and metabolite. Info
Publikováno v:
Journal of Pharmaceutical Sciences. 101:4337-4346
A simulation study was done to determine if 72 h is the most informative sampling duration for bioequivalence (BE) determination in paralleldesigned BE studies with drugs that have half-lives of at least 30 h. The impact of absorption and elimination
Autor:
David Scholfield, Nandini Cossons, Ellen Q. Wang, Ahmed El-Tahtawy, Amanda Darekar, Bimal Malhotra, T.J. Crook, Pramod P. Reddy
Publikováno v:
Journal of Pediatric Urology. 8:336-342
Objective To determine the pharmacokinetics, safety and tolerability of fesoterodine, and assess the utility of 3-day bladder diaries (exploratory objective) in pediatric subjects with neurogenic detrusor overactivity or idiopathic overactive bladder
Publikováno v:
The Journal of Clinical Pharmacology. 46:433-442
Young children are often undertreated for pain. One barrier to effective pain treatment is understanding the pharmacokinetic behavior of analgesics in this age group. Oxycodone is a commonly prescribed opioid for severe pain, yet little is known abou
Publikováno v:
The Journal of Clinical Pharmacology. 45:547-554
Hydromorphone hydrochloride extended release (HHER) is a multiparticulate melt-extrusion pellet capsule formulation administered q24h. Study 1 investigated the bioavailability of 24-mg HHER fed, as well as 24-mg and 12-mgHHER and 8-mg hydromorphone h
Autor:
William, Knebel, Marc R, Gastonguay, Bimal, Malhotra, Ahmed, El-Tahtawy, Frank, Jen, Kuan, Gandelman
Publikováno v:
Journal of clinical pharmacology. 53(5)
The population pharmacokinetics (PPK) of atorvastatin and its principal active metabolite, o-hydroxyatorvastatin, were described in 6-17 years old pediatric hypercholesterolemia patients with a 2-compartment model for both parent and metabolite. Info
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 2, Iss 5, p e236 (2008)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background A recent drug interaction study reported that when azithromycin was administered with the combination of ivermectin and albendazole, there were modest increases in ivermectin pharmacokinetic parameters. Data from this study were reanalyzed
Autor:
Hendrikus J. M. Lemmens, Ahmed El-Tahtawy, Donald R. Stanski, D. Russell Wada, Catherine Munera
Publikováno v:
Contemporary clinical trials. 27(2)
Background and Objective Enrichment strategies which select subjects who appear to respond to the drug have been used in drug studies to demonstrate clinical efficacy. We have used clinical trial simulation techniques to examine factors that are rele
Autor:
David R. Staskin, Zhonghong Guan, Vik Khullar, Linda Cardozo, Ahmed El-Tahtawy, Bimal Malhotra
Publikováno v:
BMC Urology
BMC Urology, Vol 10, Iss 1, p 14 (2010)
BMC Urology, Vol 10, Iss 1, p 14 (2010)
Background Fesoterodine is an antimuscarinic for the treatment of overactive bladder, a syndrome of urgency, with or without urgency urinary incontinence (UUI), usually with increased daytime frequency and nocturia. Our objective was to develop predi