Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ahmed Ali Chughtai"'
Effective Radiosensitization of Bladder Cancer Cells by Pharmacological Inhibition of DNA-PK and ATR
Autor:
Ahmed Ali Chughtai, Julia Pannhausen, Pia Dinger, Julia Wirtz, Ruth Knüchel, Nadine T. Gaisa, Michael J. Eble, Michael Rose
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1277 (2022)
This study aims at analyzing the impact of the pharmacological inhibition of DNA damage response (DDR) targets (DNA-PK and ATR) on radiosensitization of bladder cancer cell lines of different molecular/histological subtypes. Applying DNA-PK (AZD7648)
Externí odkaz:
https://doaj.org/article/fb74b80665734bf990fe7ca3c7ac4444
Autor:
Jan Philipp Novotný, Ahmed Ali Chughtai, Markéta Kostrouchová, Veronika Kostrouchová, David Kostrouch, Filip Kaššák, Radek Kaňa, Bernd Schierwater, Marta Kostrouchová, Zdenek Kostrouch
Publikováno v:
PeerJ, Vol 5, p e3789 (2017)
Trichoplax adhaerens, the only known species of Placozoa is likely to be closely related to an early metazoan that preceded branching of Cnidaria and Bilateria. This animal species is surprisingly well adapted to free life in the World Ocean inhabiti
Externí odkaz:
https://doaj.org/article/2b07b8b100de488095be0dc717d0c9ec
Autor:
Ahmed Ali Chughtai, Filip Kaššák, Markéta Kostrouchová, Jan Philipp Novotný, Michael W. Krause, Vladimír Saudek, Zdenek Kostrouch, Marta Kostrouchová
Publikováno v:
PeerJ, Vol 3, p e1213 (2015)
Perilipins are lipid droplet surface proteins that contribute to fat metabolism by controlling the access of lipids to lipolytic enzymes. Perilipins have been identified in organisms as diverse as metazoa, fungi, and amoebas but strikingly not in nem
Externí odkaz:
https://doaj.org/article/e4b114b8d6104de2b47a9822007d6588
Publikováno v:
Strahlentherapie und Onkologie. 195:383-392
Purpose: To assess the reproducibility of the dose–volume distribution of the initial simulation CT, generated using volumetric modulated arc therapy (VMAT) planning, during the radiotherapy of the prostatic bed based on weekly cone beam CTs (CBCT)
Neutral lipids and namely triacyl-glycerols (TAGs) are the prevalent excess energy storage molecules in all eukaryotic organisms. They are universally organized in active cytoplasmic organelles called lipid droplets (LDs) and their breakdown is perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5bf9942895c363701bf4eaa742334e
Autor:
Zdenek Kostrouch, Ahmed Ali Chughtai, Filip Kaššák, Marta Kostrouchová, Bernd Schierwater, M Kostrouchová, Radek Kaňa, David Kostrouch, Jan Philipp Novotný, Veronika Kostrouchová
Publikováno v:
PeerJ, Vol 5, p e3789 (2017)
PeerJ
PeerJ
Trichoplax adhaerens, the only known species of Placozoa is likely to be closely related to an early metazoan that preceded branching of Cnidaria and Bilateria. This animal species is surprisingly well adapted to free life in the World Ocean inhabiti
Autor:
David Kostrouch, Filip Kaššák, Bernd Schierwater, Radek Kaňa, Marta Kostrouchová, M Kostrouchová, Veronika Kostrouchová, Zdenek Kostrouch, Jan Philipp Novotný, Ahmed Ali Chughtai
Trichoplax adhaerens, the only known species of Placozoa is likely to be closely related to an early metazoan that preceded branching of Cnidaria and Bilateria. This animal species is surprisingly well adapted to free life in the World Ocean inhabiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57812490bb7ccb94d09982a617762dd9
Autor:
Aleš Benda, Zdeněk Kostrouch, M Kostrouchová, Jan Philipp Novotný, Veronika Kostrouchová, Michael W. Krause, David Kostrouch, Marta Kostrouchová, Filip Kaššák, Vladimir Saudek, Ahmed Ali Chughtai
Publikováno v:
PeerJ, Vol 5, p e3390 (2017)
PeerJ
PeerJ
The evolutionarily conserved Mediator complex is a critical player in regulating transcription. Comprised of approximately two dozen proteins, the Mediator integrates diverse regulatory signals through direct protein-protein interactions that, in tur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe64ca9e9a43869b376c974b422b16ef
https://doi.org/10.7287/peerj.preprints.2530v1
https://doi.org/10.7287/peerj.preprints.2530v1
Autor:
Jan Philipp Novotný, Filip Kaššák, M Kostrouchová, Marta Kostrouchová, Michael W. Krause, Vladimir Saudek, Ahmed Ali Chughtai, Zdenek Kostrouch
Publikováno v:
PeerJ, Vol 3, p e1213 (2015)
PeerJ
PeerJ
Perilipins are lipid droplet surface proteins that contribute to fat metabolism by controlling the access of lipids to lipolytic enzymes. Perilipins have been identified in organisms as diverse as metazoa, fungi, and amoebas but strikingly not in nem
Autor:
Veronika Kostrouchová, Zdeněk Kostrouch, Jan Philipp Novotný, P Yilma, Marta Kostrouchová, David Kostrouch, Petr Novák, M Kostrouchová, Ahmed Ali Chughtai
Publikováno v:
Journal of proteomics. 110
SKIP and BIR are evolutionarily conserved proteins; SKIP (SKP-1) is a known transcription and splicing cofactor while BIR-1/Survivin regulates cell division, gene expression and development. Their loss of function induces overlapping developmental ph