Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ahmed Adel Ali Youssef"'
Autor:
Sagar Narala, Dinesh Nyavanandi, Preethi Mandati, Ahmed Adel Ali Youssef, Abdullah Alzahrani, Praveen Kolimi, Feng Zhang, Michael Repka
Publikováno v:
International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100156- (2023)
This work developed high drug-load pellets for colon targeting in minimal steps by coupling hot-melt extrusion (HME) with a die-surface cutting pelletizer, offering a potential continuous pellet manufacturing process. Ketoprofen (KTP) was selected as
Externí odkaz:
https://doaj.org/article/cba887c0e9554274982da1e0682ec6d7
Autor:
Prateek Uttreja, Ahmed Adel Ali Youssef, Indrajeet Karnik, Kavish Sanil, Nagarjuna Narala, Honghe Wang, Rasha M. Elkanayati, Sateesh Kumar Vemula, Michael A. Repka
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 324 (2024)
Quetiapine fumarate (QTF) was approved for the treatment of schizophrenia and acute manic episodes. QTF can also be used as an adjunctive treatment for major depressive disorders. QTF oral bioavailability is limited due to its poor aqueous solubility
Externí odkaz:
https://doaj.org/article/98c7924a950b4c88abd6f53038b4ab0e
Autor:
Siva Ram Munnangi, Ahmed Adel Ali Youssef, Nagarjuna Narala, Preethi Lakkala, Sateesh Kumar Vemula, Rohit Alluri, Feng Zhang, Micheal A. Repka
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2203 (2023)
Conventional cyclodextrin complexation enhances the solubility of poorly soluble drugs but is solvent-intensive and environmentally unfavorable. This study evaluated solvent-free hot-melt extrusion (HME) for forming cyclodextrin inclusion complexes t
Externí odkaz:
https://doaj.org/article/2f1700787eac4afc800679527ff932b2
Autor:
Poorva H. Joshi, Ahmed Adel Ali Youssef, Mihir Ghonge, Corinne Varner, Siddharth Tripathi, Narendar Dudhipala, Soumyajit Majumdar
Publikováno v:
Antibiotics, Vol 12, Iss 8, p 1318 (2023)
Bacterial conjunctivitis (BC) entails inflammation of the ocular mucous membrane. Early effective treatment of BC can prevent the spread of the infection to the intraocular tissues, which could lead to bacterial endophthalmitis or serious visual disa
Externí odkaz:
https://doaj.org/article/58c12e4f80e341b795b7e1ad8063a34d
Autor:
Samir Senapati, Ahmed Adel Ali Youssef, Corinne Sweeney, Chuntian Cai, Narendar Dudhipala, Soumyajit Majumdar
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2585 (2022)
Cannabidiol (CBD) is the major non-psychoactive and most widely studied of the cannabinoid constituents and has great therapeutic potential in a variety of diseases. However, contradictory reports in the literature with respect to CBD’s effect on i
Externí odkaz:
https://doaj.org/article/0b50b1ed51dc4c148280f7e06cc4c25a
Publikováno v:
Cells, Vol 11, Iss 15, p 2439 (2022)
Wound healing is highly specialized dynamic multiple phase process for the repair of damaged/injured tissues through an intricate mechanism. Any failure in the normal wound healing process results in abnormal scar formation, and chronic state which i
Externí odkaz:
https://doaj.org/article/42d0faa8bfab4dcebf0973ee8a096b72
Autor:
Ahmed Adel Ali Youssef, Ruchi Thakkar, Samir Senapati, Poorva H. Joshi, Narendar Dudhipala, Soumyajit Majumdar
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1246 (2022)
Ocular bacterial infections can lead to serious visual disability without proper treatment. Moxifloxacin (MOX) has been approved by the US Food and Drug Administration as a monotherapy for ocular bacterial infections and is available commercially as
Externí odkaz:
https://doaj.org/article/a706e4bbbe9f401197795367aa874e42
Publikováno v:
Molecules, Vol 26, Iss 24, p 7538 (2021)
Irbesartan (IR) is an angiotensin II receptor antagonist drug with antihypertensive activity. IR bioavailability is limited due to poor solubility and first-pass metabolism. The current investigation aimed to design, develop, and characterize the cyc
Externí odkaz:
https://doaj.org/article/5b68c00c660b4c88ab959588eced3a98
Publikováno v:
Pharmaceuticals, Vol 14, Iss 3, p 210 (2021)
Bacterial keratitis (BK) is a critical ocular infection that can lead to serious visual disability. Ciprofloxacin (CIP), moxifloxacin (MOX), and levofloxacin (LFX) have been accepted as monotherapies by the US Food and Drug Administration for BK trea
Externí odkaz:
https://doaj.org/article/100cff3582ca4591a58152d06aaf9279
Autor:
Siva Ram Munnangi, Ahmed Adel Ali Youssef, Nagarjuna Narala, Preethi Lakkala, Sagar Narala, Sateesh Kumar Vemula, Michael Repka
Publikováno v:
Pharmaceutical Research.