Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ahmed Abdelbaki"'
Percutaneous Image-Guided Cryoablation of Metastatic Colorectal Adenocarcinoma to the Abdominal Wall
Publikováno v:
The Arab Journal of Interventional Radiology, Vol 07, Iss 01, Pp 049-052 (2023)
Abdominal wall metastases are rarely seen in primary colorectal cancer; the majority of cases are attributed to seeding from previous procedures. We report a case of percutaneous cryoablation of metastatic colorectal cancer to the abdominal wall with
Externí odkaz:
https://doaj.org/article/9b3ccdda56374eab9a19a27742f2692f
Autor:
Griffin Mcnamara, Ahmed Abdelbaki, Jeremy Mccarver, David Owens, Ali Malik, Keith Pereira, Alejandro Mendez
Publikováno v:
The Arab Journal of Interventional Radiology, Vol 06, Iss 02, Pp 099-101 (2022)
Adrenal myelolipomas are largely benign, non-functioning, and asymptomatic adrenal tumors found incidentally on imaging. These tumors have an extremely low incidence and are exceedingly rare. We report a case of trans-radial embolization of hemorrhag
Externí odkaz:
https://doaj.org/article/04b66c36b2ee4192bb3517504e9a89d1
Autor:
Richard Wang, Camilla Ascanelli, Ahmed Abdelbaki, Alex Fung, Tim Rasmusson, Iacovos Michaelides, Karen Roberts, Catherine Lindon
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Wang et al develop tools to target the mitotic regulator AURKA by synthesising PROTACs based on the inhibitor MLN8237. They find that the new PROTAC compound efficiently clears cytoplasmic and mitotic spindle-associated AURKA but does not eliminate A
Externí odkaz:
https://doaj.org/article/465f730a69b64dfb9fe0a36d0ac01429
Publikováno v:
Journal of the Egyptian Ophthalmological Society, Vol 114, Iss 2, Pp 35-41 (2021)
Purpose To discuss the effect of coronavirus disease 2019 (COVID-19) pandemic on ophthalmology practice and share our experience to ensure a continual ophthalmology service to the patients at Cairo University Hospital. Patients and methods This is a
Externí odkaz:
https://doaj.org/article/5ab87fe51321447cbecc26028f887e55
Autor:
Rhys Grant, Ahmed Abdelbaki, Alessia Bertoldi, Maria P. Gavilan, Jörg Mansfeld, David M. Glover, Catherine Lindon
Publikováno v:
Open Biology, Vol 8, Iss 6 (2018)
Aurora A kinase (AURKA) is a major regulator of mitosis and an important driver of cancer progression. The roles of AURKA outside of mitosis, and how these might contribute to cancer progression, are not well understood. Here, we show that a fraction
Externí odkaz:
https://doaj.org/article/56055bb871ef4aa2b57c054507b02235
Publikováno v:
Case Reports in Vascular Medicine, Vol 2017 (2017)
Hepatic artery pseudoaneurysm (HAP) incidence is rising due to more common use of endoscopic and percutaneous hepatic interventions. HAP is potentially fatal, as it could lead to sudden life-threatening hemorrhage. HAP can be intrahepatic or extrahep
Externí odkaz:
https://doaj.org/article/e04c98f60c8c45cbac52856d252022fd
Autor:
Ahmed Abdelbaki, Camilla Ascanelli, Cynthia N. Okoye, Begum Akman, Giacomo Janson, Mingwei Min, Chiara Marcozzi, Anja Hagting, Rhys Grant, Maria De Luca, Italia Anna Asteriti, Giulia Guarguaglini, Alessandro Paiardini, Catherine Lindon
Mitotic kinase Aurora A (AURKA) diverges from other kinases in its multiple active conformations that may explain its interphase roles and association with cancer, and the limited efficacy of drugs targeting the kinase pocket. Regulation of AURKA act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81a712b9078b47556ddd991abb74a9b0
https://doi.org/10.1101/2022.01.31.478464
https://doi.org/10.1101/2022.01.31.478464
Autor:
Ahmed, Abdelbaki, Camilla, Ascanelli, Cynthia N, Okoye, H Begum, Akman, Giacomo, Janson, Mingwei, Min, Chiara, Marcozzi, Anja, Hagting, Rhys, Grant, Maria, De Luca, Italia Anna, Asteriti, Giulia, Guarguaglini, Alessandro, Paiardini, Catherine, Lindon
Publikováno v:
Life science alliance. 6(2)
Mitotic kinase Aurora A (AURKA) diverges from other kinases in its multiple active conformations that may explain its interphase roles and the limited efficacy of drugs targeting the kinase pocket. Regulation of AURKA activity by the cell is critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ced7523e39758a1409fae578949b247
https://pubmed.ncbi.nlm.nih.gov/36450448
https://pubmed.ncbi.nlm.nih.gov/36450448
Autor:
Leila Christie, Phil Snell, Alice E. Chen, Paul Blakeley, Rabi Odia, Kathy K. Niakan, Kay Elder, Mahesh Sangrithi, Prabhakaran Munusamy, Ahmed Abdelbaki, Paul Serhal, Norah M. E. Fogarty, Liani G. Devito, Afshan McCarthy
During the first week of development, human embryos form a blastocyst comprised of an inner cell mass and trophectoderm (TE) cells, the latter of which are progenitors of placental trophoblast. Here we investigated the expression of transcripts in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e18df636cea561abfa01e07ed3978a74
https://doi.org/10.1101/2021.08.18.456785
https://doi.org/10.1101/2021.08.18.456785
Autor:
Karen Roberts, Iacovos N Michaelides, Richard Wang, Ahmed Abdelbaki, Catherine Lindon, Alex Fung, Camilla Ascanelli, Tim Rasmusson
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Funder: AstraZeneca; doi: https://doi.org/10.13039/100004325
Targeted protein degradation tools are becoming a new therapeutic modality, allowing small molecule ligands to be reformulated as heterobifunctional molecules (PROteolysis Targeting Ch
Targeted protein degradation tools are becoming a new therapeutic modality, allowing small molecule ligands to be reformulated as heterobifunctional molecules (PROteolysis Targeting Ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4175155678a9205e311961c0ad9cf506