Structure-Activity Relationship Studies of N- and C-Terminally Modified Secretin Analogs for the Human Secretin Receptor

Autor: Billy K. C. Chow, Jérôme Leprince, Kailash Singh, Ahmed Aa Allam, Jamaan S. Ajarem, Aloysius Wilfred Raj Arokiaraj, Vijayalakshmi Senthil, David Vaudry, Benjamin Lefranc

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2016, 11 (3), ⟨10.1371/journal.pone.0149359⟩
PLoS ONE, Public Library of Science, 2016, 11 (3), pp.e0149359. ⟨10.1371/journal.pone.0149359⟩
PLoS ONE, Public Library of Science, 2016, 11 (10), ⟨10.1371/journal.pone.0165770⟩
PLoS ONE, Vol 11, Iss 10, p e0165770 (2016)
PLoS ONE, Vol 11, Iss 3, p e0149359 (2016)

The pleiotropic role of human secretin (hSCT) validates its potential use as a therapeutic agent. Nevertheless, the structure of secretin in complex with its receptor is necessary to develop a suitable therapeutic agent. Therefore, in an effort to de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9ac21910deb4b765a36b08ca63d0f0
https://hal-normandie-univ.archives-ouvertes.fr/hal-01939270