Aprepitant boasted a protective effect against olanzapine-induced metabolic syndrome and its subsequent hepatic, renal, and ovarian dysfunction; Role of IGF 1 /p-AKT/FOXO 1 and NFκB/IL-1β/TNF-α signaling pathways in female Wistar albino rats.

Autor: Mohyeldin RH; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt. Electronic address: reham.hassan@deraya.edu.eg., Abdelzaher WY; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia 61519, Egypt. Electronic address: walaa.hamada@mu.edu.eg., Sharata EE; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt. Electronic address: ehab.essam@deraya.edu.eg., Mohamed HMA; Department of Obstetrics and Gynecology, Faculty of Medicine, Minia University, Minia 61519, Egypt., Ahmed MYM; Department of Obstetrics and Gynecology, Faculty of Medicine, Minia University, Minia 61519, Egypt., Attia JZ; Department of Anesthesia and I.C.U, Faculty of Medicine, Minia University, Minia 61519, Egypt., Atta M; Department of Anatomy, Faculty of Medicine, Minia University, Minia 61519, Egypt., Saleh RK; Department of Pathology, Faculty of Medicine, Minia University, Minia 61519, Egypt. Electronic address: Rabeh.Saleh@mu.edu.eg., Ghallab EA; Department of Biochemistry, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt. Electronic address: elshimaa.amir@deraya.edu.eg., Marey H; Department of Biochemistry, Faculty of Medicine, Minia University, Minia 61519, Egypt. Electronic address: heba.ebrahim@mu.edu.eg., Elrehany MA; Department of Biochemistry, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt. Electronic address: Mahmoud.elrehany@deraya.edu.eg., Rofaeil RR; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Deraya University, Minia 61111, Egypt; Department of Medical Pharmacology, Faculty of Medicine, Minia University, Minia 61519, Egypt. Electronic address: remon.roshdy@deraya.edu.

Publikováno v: Biochemical pharmacology [Biochem Pharmacol] 2024 Mar; Vol. 221, pp. 116020. Date of Electronic Publication: 2024 Jan 17.