Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Ahmed, Hamaï"'
Autor:
Yao Xiang, Jorge Mata-Garrido, Yuanji Fu, Christophe Desterke, Eric Batsché, Ahmed Hamaï, Christine Sedlik, Youssouf Sereme, David Skurnik, Abdelali Jalil, Rachel Onifarasoaniaina, Eric Frapy, Jean-Christophe Beche, Razack Alao, Eliane Piaggio, Laurence Arbibe, Yunhua Chang
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1404-1426 (2024)
Abstract As an important immune stimulator and modulator, IFNγ is crucial for gut homeostasis and its dysregulation links to diverse colon pathologies, such as colitis and colorectal cancer (CRC). Here, we demonstrated that the epigenetic regulator,
Externí odkaz:
https://doaj.org/article/de2e44b1297c4b6381469b61856d34e2
Autor:
Emma Cosialls, Emeline Pacreau, Clémence Duruel, Sara Ceccacci, Rima Elhage, Christophe Desterke, Kevin Roger, Chiara Guerrera, Romane Ducloux, Sylvie Souquere, Gérard Pierron, Ivan Nemazanyy, Mairead Kelly, Elise Dalmas, Yunhua Chang, Vincent Goffin, Maryam Mehrpour, Ahmed Hamaï
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-14 (2023)
Abstract Ferroptosis constitutes a promising therapeutic strategy against cancer by efficiently targeting the highly tumorigenic and treatment-resistant cancer stem cells (CSCs). We previously showed that the lysosomal iron-targeting drug Salinomycin
Externí odkaz:
https://doaj.org/article/5ad5e737bb114cf494300de72b4fe890
Autor:
Rima Elhage, Mairead Kelly, Nicolas Goudin, Jérôme Megret, Agnès Legrand, Ivan Nemazanyy, Cécilia Patitucci, Véronique Quellec, Timothy Wai, Ahmed Hamaï, Sophie Ezine
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Several studies demonstrated that mitochondrial dynamics and metabolic pathways control T cell fate in the periphery. However, little is known about their implication in thymocyte development. Our results showed that thymic progenitors (CD3-CD4-CD8-
Externí odkaz:
https://doaj.org/article/8179045982c54527bc94f4e88502b947
Publikováno v:
Cancers, Vol 16, Iss 1, p 155 (2023)
(1) Background: Triple-negative breast cancer (TNBC) is a distinct subgroup of breast cancer presenting a high level of recurrence, and neo-adjuvant chemotherapy is beneficial in its therapy management. Anti-PD-L1 immunotherapy improves the effect of
Externí odkaz:
https://doaj.org/article/e7e326ca8c3744dd92e028456c606187
Autor:
Christophe Desterke, Emma Cosialls, Yao Xiang, Rima Elhage, Clémence Duruel, Yunhua Chang, Ahmed Hamaï
Publikováno v:
Cells, Vol 12, Iss 17, p 2176 (2023)
(1) Background: Breast cancer is a frequent heterogeneous disorder diagnosed in women and causes a high number of mortality among this population due to rapid metastasis and disease recurrence. Ferroptosis can inhibit breast cancer cell growth, impro
Externí odkaz:
https://doaj.org/article/f4e952652b864e7d82ef70cc4b125d7d
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/afbd22f59e2f45fda6eace4bcfd6bac2
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-17 (2020)
Abstract Cancer is now considered as a heterogeneous ecosystem in which tumor cells collaborate with each other and with host cells in their microenvironment. As circumstances change, the ecosystem evolves to ensure the survival and growth of the can
Externí odkaz:
https://doaj.org/article/6d9187a6a0764dd68afbaa5de9edd588
Publikováno v:
Cells, Vol 11, Iss 15, p 2324 (2022)
Autophagy, a lysosome-mediated cellular degradation pathway, recycles intracellular components to maintain metabolic balance and survival. Autophagy plays an important role in tumor immunotherapy as a “double-edged sword” that can both promote an
Externí odkaz:
https://doaj.org/article/cc4670a6adb44a4c9067408cb3ec14c8
Publikováno v:
Cells, Vol 10, Iss 11, p 2981 (2021)
Cancer stem cells (CSCs) are a distinct subpopulation of tumor cells with stem cell-like features. Able to initiate and sustain tumor growth and mostly resistant to anti-cancer therapies, they are thought responsible for tumor recurrence and metastas
Externí odkaz:
https://doaj.org/article/4a553e184e75440a9d11b2a53d851e8b
Autor:
Danila Valmori, Maha Ayyoub, Jaafar Bennouna, Jean-Yves Douillard, Sandrine Hiret, Hélène Senellart, Karine Duperrier-Amouriaux, Isabelle Raimbaud, Pascale Pignon, Ahmed Hamaï
PDF file - 49K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884e86de71f0e14e0898ccf849c69506
https://doi.org/10.1158/0008-5472.22394256.v1
https://doi.org/10.1158/0008-5472.22394256.v1