Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ahmad W. Almawi"'
Publikováno v:
Biology Open, Vol 3, Iss 6, Pp 418-430 (2014)
In conditions of proteasomal impairment, the build-up of damaged or misfolded proteins activates a cellular response leading to the recruitment of damaged proteins into perinuclear aggregates called aggresomes. Aggresome formation involves the retrog
Externí odkaz:
https://doaj.org/article/0c0882f1ed8948b6ac30995bd754611d
Autor:
Ahmad W. Almawi, Javier Rodríguez González, Laurence Langlois-Lemay, Alba Guarné, Giuseppe Melacini, Damien D’Amours, Stephen Boulton
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Polo-like kinases (Plks) are key cell cycle regulators. They contain a kinase domain followed by a polo-box domain that recognizes phosphorylated substrates and enhances their phosphorylation. The regulatory subunit of the Dbf4-dependent kinase compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2a8d23138d1a31e8802db3ac21179f
http://link.springer.com/article/10.1038/s41598-020-60344-4
http://link.springer.com/article/10.1038/s41598-020-60344-4
Publikováno v:
Biology Open, Vol 3, Iss 6, Pp 418-430 (2014)
Biology Open
Biology Open
In conditions of proteasomal impairment, the build-up of damaged or misfolded proteins activates a cellular response leading to the recruitment of damaged proteins into perinuclear aggregates called aggresomes. Aggresome formation involves the retrog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c090660b4444b3ef118edffcb7786a92
http://bio.biologists.org/content/3/6/418
http://bio.biologists.org/content/3/6/418
Autor:
Bernard P. Duncker, Christine Chieh-Lin Lai, Larasati, Ahmad W. Almawi, Trevor F. Moraes, Polina Myrox, Alba Guarné, Stephen Boulton, Rodolfo Ghirlando, Giuseppe Melacini, Lindsay A. Matthews
Publikováno v:
Scientific Reports
Forkhead-associated (FHA) domains are phosphopeptide recognition modules found in many signaling proteins. The Saccharomyces cerevisiae protein kinase Rad53 is a key regulator of the DNA damage checkpoint and uses its two FHA domains to interact with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ba2a9f56820593a5059a1db3adb406
https://doi.org/10.1038/srep34237
https://doi.org/10.1038/srep34237
Publikováno v:
Progress in biophysics and molecular biology. 127
Forkhead-associated (FHA) domains are small phosphopeptide recognition modules found in eubacterial and eukaryotic, but not archeal, genomes. Although they were originally found in forkhead-type transcription factors, they have now been identified in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ddbc4675624fdeee3b30e135f0d814
https://pubmed.ncbi.nlm.nih.gov/27939759
https://pubmed.ncbi.nlm.nih.gov/27939759
Autor:
Eman A. Dashti, Sose H. Keleshian, Ahmad W. Almawi, Noha Irani-Hakime, Wassim Y. Almawi, Akram Echtay, A.S. Al-Busaidi, Rita Nemr
Publikováno v:
Diabetes Research and Clinical Practice. 96:225-229
Several genome-wide association studies and replication analyses have identified common variation at the insulin-like binding protein 2 (IGF2BP2) gene to be associated with type 2 diabetes (T2DM). The aim of this study was to replicate in a Lebanese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff67f1ff68af0a5b6c925b58e1d6f19
https://doi.org/10.1016/j.diabres.2011.12.026
https://doi.org/10.1016/j.diabres.2011.12.026
Publikováno v:
European Cytokine Network. 22:154-158
Objective. Vascular endothelial growth factor (VEGF) is a pro-angiogenic factor. Variability in VEGF expression, induced by specific VEGFA variants, are involved in angiogenesis-related disorders. This study examined the genotype distribution and fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a9d7319e65368af3af5e4c59e688bd
https://doi.org/10.1684/ecn.2011.0289
https://doi.org/10.1684/ecn.2011.0289
Publikováno v:
Reproduction (Cambridge, England). 146(2)
Protein Z (PZ) is a vitamin K-dependent factor characterized by its homology to other vitamin K-dependent factors (factors VII, IX, and X, protein C and protein S), but lacks any enzymatic activity. Instead, PZ acts as a cofactor for the inhibition o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0074a08f86bf17e5c53c2dd027bcb5f
https://pubmed.ncbi.nlm.nih.gov/23690629
https://pubmed.ncbi.nlm.nih.gov/23690629
Publikováno v:
Molecular human reproduction. 18(3)
Protein Z-dependent protease inhibitor (ZPI) is a 72 kDa single-chain serpin which inhibits the activated coagulation factors X and XI. Two non-sense polymorphisms of ZPI, R67X and W303X, were recently identified, and were linked with a prothrombotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f35841f4d2633fc3768c7b9f38f033b
https://pubmed.ncbi.nlm.nih.gov/22039093
https://pubmed.ncbi.nlm.nih.gov/22039093
Publikováno v:
Diabetes research and clinical practice. 95(2)
We investigated the association of CDKAL1 (rs7754840 and rs7756992) and CDKN2A/2B (rs10811661) variants with T2DM. Higher MAF of rs7754840 and rs7756992 were seen in patients, and both were associated with T2DM under additive, dominant, and recessive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c527ba090deac563764270e3d1065c9f
https://pubmed.ncbi.nlm.nih.gov/22119613
https://pubmed.ncbi.nlm.nih.gov/22119613