Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ahmad Seyed-Mozaffari"'
Autor:
Ahmad Seyed-Mozaffari, Sydney Archer, Jean M. Bidlack, Richard A. Kaplan, Alice Sebastian, Ian Hutchinson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1695-1700
MET-TAMO and N-CPM-MET-TAMO were prepared by the same procedure used for the corresponding 5-desmethyl compounds, TAMO and N-CPM-TAMO, except that a new procedure was employed to synthesize the intermediate, 14β-amino-7,8-dihydromorphinone. Both MET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a96ffda614e87a0a5f55cab6f86311a7
https://doi.org/10.1016/0960-894x(95)00287-4
https://doi.org/10.1016/0960-894x(95)00287-4
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::272021fb62fd41407f2997f31c1c14b1
https://doi.org/10.1002/chin.199145282
https://doi.org/10.1002/chin.199145282
Publikováno v:
Journal of immunological methods. 201(2)
An immunofluorescent technique that is more sensitive than radioligand binding was developed in order to detect opioid receptors expressed on leukocytes. The current study was designed to optimize the method for fluorescently labeling kappa opioid re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3301a36273439183fc710b37ab447893
https://pubmed.ncbi.nlm.nih.gov/9050939
https://pubmed.ncbi.nlm.nih.gov/9050939
Autor:
Stanley D. Click, Lindsay B. Hough, Sandra M. Keefner, Sydney Archer, Ahmad Seyed-Mozaffari, Carol A. Gallagher
Publikováno v:
Biochemical pharmacology. 49(1)
A sensitive and highly selective analytical chemical method for measuring the indole alkaloid ibogaine in biological samples has been developed. The method utilizes organic extraction, derivatization with trifluoroacetic anhydride, and detection by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76ed6de113c8b9fd251119eaa1c5f3d
https://pubmed.ncbi.nlm.nih.gov/7840786
https://pubmed.ncbi.nlm.nih.gov/7840786
Publikováno v:
Journal of medicinal chemistry. 37(11)
14 alpha,14' beta-[Dithiobis[(2-oxo-2,1-ethanediyl)imino]] bis(7,8-dihydromorphinone) (TAMO) (13) was synthesized by condensing 14 beta-amino-7,8-dihydromorphine (4) with acetylthioglycolyl chloride and hydrolyzing the resulting ester with mild base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff3815ad3213da878618fe66c856a37
https://pubmed.ncbi.nlm.nih.gov/7515442
https://pubmed.ncbi.nlm.nih.gov/7515442
Publikováno v:
European journal of pharmacology. 240(2-3)
This study evaluated the supraspinal opioid effects of 14 beta-(bromoacetamido)-7,8-dihydro-N(cyclopropylmethyl)-normorphinone+ ++ (N-CPM-H2BAMO) in the mouse acetic acid-induced writhing and tail-flick assays. In the writhing test, N-CPM-H2BAMO prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7272288819fb4514b33edab6672ec717
https://pubmed.ncbi.nlm.nih.gov/7694857
https://pubmed.ncbi.nlm.nih.gov/7694857
Autor:
Richard A. Kaplan, Jean M. Bidlack, Sydney Archer, Ramu A. Subbramanian, Ahmad Seyed-Mozaffari
Publikováno v:
Biochemistry. 32(26)
[3H]-14 beta-(Bromoacetamido)-7,8-dihydromorphine ([3H]H2BAM) was synthesized and tested for its ability to selectively label mu opioid receptors in bovine striatal membranes. Incubating membranes with N-tosyl-L-phenylalanine chloromethyl ketone and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d665190a70cca874972a9a010b2c7e5e
https://pubmed.ncbi.nlm.nih.gov/7687147
https://pubmed.ncbi.nlm.nih.gov/7687147
Autor:
Li-Qun Fan, Jacob M. Hiller, Eric J. Simon, Sydney Archer, Arthur G. Schultz, Ahmad Seyed-Mozaffari
Publikováno v:
Life sciences. 53(14)
Two affinity ligands, 6 beta-(5-Azido-2-nitrophenacetamido) 14 beta-hydroxy-7,8-dihydromorphinone (4) and 6 beta-(5-azido-2-nitrophenacetamido) 14 beta-hydroxy-7,8-dihydro-N- cyclopropylmethylnormorphinone (5) bind reversibly to opioid receptors pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f497483de3bebc5562ce1b988fc7006
https://pubmed.ncbi.nlm.nih.gov/8396706
https://pubmed.ncbi.nlm.nih.gov/8396706
Publikováno v:
Biochemical pharmacology. 43(2)
Alkylation of sarcosine with 4-chloro-nitrobenzo-2-oxa-1,3-diazole (NBD-chloride) furnished a fluorescent tag that was coupled with a tetrahydrothebaine derivative and beta-naltrexamine, respectively, to yield the fluorescent opioids 7 alpha-(1R)-1-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f624a7805739f55e3766a6aa8ba78ba7
https://pubmed.ncbi.nlm.nih.gov/1371213
https://pubmed.ncbi.nlm.nih.gov/1371213
Autor:
Donato Cioli, Sydney Archer, Livia Pica-Mattoccia, Wageeh El-Hamouly, Ahmad Seyed-Mozaffari, Richard H. Butler
Publikováno v:
Molecular and biochemical parasitology. 43(1)
Condensation of hycanthone N-methylcarbamate (HNMC) with deoxyguanosine (dG) furnished a mixture of the N-1 and N2 adducts which were purified and characterized as their acetates. Condensation of HNMC with thymidine (T) gave the N-3 adduct in poor yi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c511c500e8a865e644f812c0ce67de6a
https://pubmed.ncbi.nlm.nih.gov/2290447
https://pubmed.ncbi.nlm.nih.gov/2290447