Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ahmad R Mehdipour"'
Autor:
Schara Safarian, Helen K. Opel-Reading, Di Wu, Ahmad R. Mehdipour, Kiel Hards, Liam K. Harold, Melanie Radloff, Ian Stewart, Sonja Welsch, Gerhard Hummer, Gregory M. Cook, Kurt L. Krause, Hartmut Michel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
M. tuberculosis cytochrome bd oxidase is of interest as a TB drug target. Here, the authors present the 2.5 Å cryo-EM structure of M. tuberculosis cytochrome bd oxidase and identify a disulfide bond within the canonical quinol binding and oxidation
Externí odkaz:
https://doaj.org/article/d59d3dd24560451195a1764a95c9ea6d
Autor:
Di Wu, Ahmad R. Mehdipour, Franziska Finke, Hojjat G. Goojani, Roan R. Groh, Tamara N. Grund, Thomas M. B. Reichhart, Rita Zimmermann, Sonja Welsch, Dirk Bald, Mark Shepherd, Gerhard Hummer, Schara Safarian
Publikováno v:
Nature Chemical Biology
Iron-bound cyclic tetrapyrroles (hemes) are redox-active cofactors in bioenergetic enzymes. However, the mechanisms of heme transport and insertion into respiratory chain complexes remain unclear. Here, we used cellular, biochemical, structural and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f756f6a1e9734e0b890fa2152c92756
https://doi.org/10.1038/s41589-023-01314-5
https://doi.org/10.1038/s41589-023-01314-5
Autor:
Radhika Khera, Ahmad R Mehdipour, Jani R Bolla, Joerg Kahnt, Sonja Welsch, Ulrich Ermler, Cornelia Muenke, Carol V Robinson, Gerhard Hummer, Hao Xie, Hartmut Michel
Publikováno v:
The EMBO Journal
Bacteria utilize small extracellular molecules to communicate in order to collectively coordinate their behaviors in response to the population density. Autoinducer-2 (AI-2), a universal molecule for both intra- and inter-species communication, is in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6499dcc5cc1c1bba33c83a128fe5ab2a
https://doi.org/10.15252/embj.2021109990
https://doi.org/10.15252/embj.2021109990
Autor:
Di Wu, Ahmad R Mehdipour, Franziska Finke, Hojjat G Goojani, Roan R Groh, Tamara N Grund, Thomas MB Reichhart, Rita Zimmermann, Sonja Welsch, Dirk Bald, Mark Shepherd, Gerhard Hummer, Schara Safarian
Iron-bound cyclic tetrapyrroles (hemes) are key redox-active cofactors in membrane-integrated oxygen reductases and other bioenergetic enzymes. However, the mechanisms of heme transport and insertion into respiratory chain complexes remain unclear. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::802fbb670b4ec325e7b419f88c905fb0
https://doi.org/10.1101/2022.04.07.487047
https://doi.org/10.1101/2022.04.07.487047
Publikováno v:
Chemical biologydrug design. 76(5)
Multidrug resistance is defined as the resistance of a tumor cell to the cytotoxic action of divergent drugs used in chemotherapy. Dihydropyridines are a class of calcium channel antagonists that were discovered to have a multidrug resistance reversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c148555e67b20e80b14f7da4c2c915a
https://pubmed.ncbi.nlm.nih.gov/20925689
https://pubmed.ncbi.nlm.nih.gov/20925689
Publikováno v:
Chemical biologydrug design. 75(5)
Quantitative structure activity relationship (QSAR) analyses using a novel type of electronic descriptors called quantum topological molecular similarity (QTMS) indices were operated to describe and compare the mechanisms of toxicity of phenols towar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d946288d1e5381ced5742e8d1d497091
https://pubmed.ncbi.nlm.nih.gov/20486939
https://pubmed.ncbi.nlm.nih.gov/20486939