Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ahmad Najem"'
Autor:
Laura Soumoy, Aline Genbauffe, Lena Mouchart, Alexandra Sperone, Anne Trelcat, Léa Mukeba-Harchies, Mathilde Wells, Bertrand Blankert, Ahmad Najem, Ghanem Ghanem, Sven Saussez, Fabrice Journe
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Despite advancements in treating metastatic melanoma, many patients exhibit resistance to targeted therapies. Our study focuses on ATP1A1, a sodium pump subunit associated with cancer development. We aimed to assess ATP1A1 prognostic value i
Externí odkaz:
https://doaj.org/article/965df12f444d4467a7fa06597a96087b
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The corrosion behaviour of (Bi, Pb)-2223 samples compacted at 0.3–1.9 GPa in 0.5 M of HCl, NaCl, and NaOH solutions at 30 °C was investigated using potentiodynamic polarization curves measurements and electrochemical impedance spectroscop
Externí odkaz:
https://doaj.org/article/e3483e5364de466abae0dd28fc0d9db5
Autor:
Malak Sabbah, Ahmad Najem, Christophe Vanderkerkhove, Fabien Kert, Younes Jourani, Fabrice Journe, Ahmad Awada, Dirk Van Gestel, Ghanem E. Ghanem, Mohammad Krayem
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Melanoma is known to be a radioresistant cancer. Melanoma radioresistance can be due to several factors such as pigmentation, antioxidant defenses and high Deoxyribonucleic acid (DNA) repair efficacy. However, irradiation induces intracellular transl
Externí odkaz:
https://doaj.org/article/6af0efc13c724c449444df05984206e0
Autor:
Ahmad Najem, Mohammad Krayem, Serena Sabbah, Matilde Pesetti, Fabrice Journe, Ahmad Awada, Laurent Désaubry, Ghanem E. Ghanem
Publikováno v:
Cells, Vol 12, Iss 14, p 1855 (2023)
Despite important advances in the treatment of metastatic melanoma with the development of MAPK-targeted agents and immune checkpoint inhibitors, the majority of patients either do not respond to therapies or develop acquired resistance. Furthermore,
Externí odkaz:
https://doaj.org/article/6ce40f86795447d1bffe6e7fe1ad41b4
Autor:
Ahmad Najem, Jasper Wouters, Mohammad Krayem, Florian Rambow, Malak Sabbah, François Sales, Ahmad Awada, Stein Aerts, Fabrice Journe, Jean-Christophe Marine, Ghanem E. Ghanem
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The use of patient-derived primary cell cultures in cancer preclinical assays, including drug screens and genotoxic studies, has increased in recent years. However, their translational value is constrained by several limitations, including variabilit
Externí odkaz:
https://doaj.org/article/7246698bc874445fae20d2e08f486791
Autor:
Pashalina Kehagias, Nadège Kindt, Mohammad Krayem, Ahmad Najem, Giulia Agostini, Elena Acedo Reina, Giacomo Bregni, Francesco Sclafani, Fabrice Journe, Ahmad Awada, Ghanem E. Ghanem, Alain Hendlisz
Publikováno v:
Cells, Vol 11, Iss 22, p 3663 (2022)
Potential intrinsic resistance mechanisms to regorafenib were explored after short exposure (3 days) on five CRC cell lines (HCT-116, SW1116, LS-1034, SW480, Caco-2). The observation of senescence-like features led to the investigation of a drug-init
Externí odkaz:
https://doaj.org/article/f8491e9a6d53466e892ad25bf87c4af1
Autor:
Ahmad Najem, Laura Soumoy, Malak Sabbah, Mohammad Krayem, Ahmad Awada, Fabrice Journe, Ghanem E. Ghanem
Publikováno v:
Cells, Vol 11, Iss 7, p 1157 (2022)
Melanoma cells are notorious for their high plasticity and ability to switch back and forth between various melanoma cell states, enabling the adaptation to sub-optimal conditions and therapeutics. This phenotypic plasticity, which has gained more at
Externí odkaz:
https://doaj.org/article/1d30015de0a445c98f1a0b7f0641fd07
Autor:
Laura Soumoy, Mathilde Wells, Ahmad Najem, Mohammad Krayem, Ghanem Ghanem, Stéphanie Hambye, Sven Saussez, Bertrand Blankert, Fabrice Journe
Publikováno v:
Biology, Vol 9, Iss 8, p 218 (2020)
Melanoma is the most common cancer in young adults, with a constantly increasing incidence. Metastatic melanoma is a very aggressive cancer with a 5-year survival rate of about 22−25%. This is, in most cases, due to a lack of therapies which are ef
Externí odkaz:
https://doaj.org/article/2bae868e5a414922aeb9ba518329c47e
Autor:
Mohammad Al-Iraqi, Ahmad Najem
Publikováno v:
مجلة التربية والعلم, Vol 26, Iss 5, Pp 135-144 (2013)
ABSTRACT This research involves synthesis of some five membered heterocyclic compounds using 1,2,3,4-tetrahydroisoquinoline as a synthone. The initial step in this research involves the reaction of 1,2,3,4-tetrahydroisoquinoline with ethyl chloroacet
Externí odkaz:
https://doaj.org/article/4993bff45c8442e296c0310858f67107
Publikováno v:
Tikrit Journal of Pure Science. 22:56-64
This research paper includes synthesis and characterization of some complexes of Zn(II),Hg(II), Cd(II), Cu(II), Co(II), Ni(II) with mix ligands of saccharinate and Schiff base derived from Isatin. All the synthesized complexes have been characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb77a54784784115178d79d75cfd0e61
https://doi.org/10.25130/tjps.v22i6.791
https://doi.org/10.25130/tjps.v22i6.791