Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ahmad Moolla"'
Autor:
Nantia Othonos, Riccardo Pofi, Anastasia Arvaniti, Sarah White, Ilaria Bonaventura, Nikolaos Nikolaou, Ahmad Moolla, Thomas Marjot, Roland H. Stimson, André P. van Beek, Martijn van Faassen, Andrea M. Isidori, Elizabeth Bateman, Ross Sadler, Fredrik Karpe, Paul M. Stewart, Craig Webster, Joanne Duffy, Richard Eastell, Fatma Gossiel, Thomas Cornfield, Leanne Hodson, K. Jane Escott, Andrew Whittaker, Ufuk Kirik, Ruth L. Coleman, Charles A. B. Scott, Joanne E. Milton, Olorunsola Agbaje, Rury R. Holman, Jeremy W. Tomlinson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Glucocorticoids prescribed to limit inflammation, have significant adverse effects. Here the authors show that co-administration of AZD4017 with prednisolone in men is a potential strategy to limit adverse glucocorticoid effects.
Externí odkaz:
https://doaj.org/article/d5729cc721e9453cb5043aab11c131a3
Autor:
Jonathan M. Hazlehurst, Teegan Reina Lim, Catriona Charlton, Jack J. Miller, Laura L. Gathercole, Thomas Cornfield, Nikolaos Nikolaou, Shelley E. Harris, Ahmad Moolla, Nantia Othonos, Lisa C. Heather, Thomas Marjot, Damian J. Tyler, Carolyn Carr, Leanne Hodson, Jane McKeating, Jeremy W. Tomlinson
Publikováno v:
Metabolism Open, Vol 14, Iss , Pp 100177- (2022)
Background and aims: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver condition. It is tightly associated with an adverse metabolic phenotype (including obesity and type 2 diabetes) as well as with obstructive sleep apnoea (
Externí odkaz:
https://doaj.org/article/4594b0aa997b40519a78b4393c21a3ac
Autor:
Thomas Marjot, Charlotte J Green, Catriona A Charlton, Thomas Cornfield, Jonathan Hazlehurst, Ahmad Moolla, Sarah White, Jane Francis, Stefan Neubauer, Jeremy FL Cobbold, Leanne Hodson, Jeremy W Tomlinson
Publikováno v:
JGH Open, Vol 4, Iss 3, Pp 433-440 (2020)
Background and Aim Non‐alcoholic fatty liver disease (NAFLD) is rapidly becoming the leading indication for liver transplant and is associated with increased cardiovascular and liver mortality, yet there are no licensed therapies. Sodium‐glucose
Externí odkaz:
https://doaj.org/article/e4dd5d2c58194f9b9fc1070e71693d5a
Autor:
Sarah Ali, Sufyan Hussain, Ahmad Moolla, Tahseen Chowdhury, Rabia Nabi, Shuja Shafi, Wasim Hanif Hanif
Publikováno v:
Journal of Fasting and Health, Vol 3, Iss 3, Pp 94-96 (2015)
If you are planning on fasting and have diabetes, it is important to speak to your diabetes healthcare team as early as possible before Ramadan. For some people with diabetes, fasting can be dangerous or can cause problems to your health. Your diabet
Externí odkaz:
https://doaj.org/article/ea52b670b8a84012b8f6d8b09b69f163
Autor:
Laura L Gathercole, Nikolaos Nikolaou, Shelley E Harris, Anastasia Arvaniti, Toryn M Poolman, Jonathan M Hazlehurst, Denise V Kratschmar, Marijana Todorčević, Ahmad Moolla, Niall Dempster, Ryan C Pink, Michael F Saikali, Liz Bentley, Trevor M Penning, Claes Ohlsson, Carolyn L Cummins, Matti Poutanen, Alex Odermatt, Roger D Cox, Jeremy W Tomlinson
Publikováno v:
Journal of Endocrinology. 253:97-113
Steroid 5β-reductase (AKR1D1) plays important role in hepatic bile acid synthesis and glucocorticoid clearance. Bile acids and glucocorticoids are potent metabolic regulators, but whether AKR1D1 controls metabolic phenotype in vivo is unknown. Akr1d
Autor:
Conceicao Ismael da, Nikolaos Nikolaou, Laura Gathercole, Shelley Harris, Niall Dempster, Ahmad Moolla, Leanne Hodson, Jeremy Tomlinson
Publikováno v:
Endocrine Abstracts.
Autor:
Charlotte J Green, Thomas Marjot, John Walsby-Tickle, Catriona Charlton, Thomas Cornfield, Felix Westcott, Katherine E Pinnick, Ahmad Moolla, Jonathan M Hazlehurst, James McCullagh, Jeremy W Tomlinson, Leanne Hodson
Objective Metformin is a first-line pharmacotherapy in the treatment of type 2 diabetes, a condition closely associated with non-alcoholic fatty liver disease (NAFLD). Although metformin promotes weight loss and improves insulin sensitivity, its effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4ae4874c6c19249dd759fceb7e3d27
https://doi.org/10.1530/eje-21-0850
https://doi.org/10.1530/eje-21-0850
Autor:
Leanne Hodson, Sarah White, Nikolaos Nikolaou, Craig Webster, Andrea M. Isidori, Joanne E Duffy, Ilaria Bonaventura, Ahmad Moolla, Jonathan Hazlehurst, Thomas Marjot, Riccardo Pofi, Conor Woods, Thomas Cornfield, Jeremy W. Tomlinson, Nantia Othonos
Publikováno v:
J Clin Endocrinol Metab
Context Glucocorticoids (GCs) are commonly prescribed, but their use is associated with adverse metabolic effects. 5α-reductase inhibitors (5α-RI) are also frequently prescribed, mainly to inhibit testosterone conversion to dihydrotestosterone. How
Autor:
Jane I. Grove, Beverly A. Hughes, Jasper de Boer, Jeremy W. Tomlinson, Guruprasad P. Aithal, Angela E Taylor, Sven Francque, John Ryan, Ahmad Moolla, David Pavlov, Luc Van Gaal, Zaki Hassan-Smith, Eleanor Barnes, Lorna C Gilligan, Amin Amin, Michael Biehl, Jeremy F. L. Cobbold, Wiebke Arlt, Matthew J. Armstrong, An Verrijken, P N Newsome
Publikováno v:
Alimentary pharmacology and therapeutics
Alimentary Pharmacology & Therapeutics
Alimentary Pharmacology & Therapeutics, 51(11), 1188-1197. Wiley
Alimentary Pharmacology & Therapeutics
Alimentary Pharmacology & Therapeutics, 51(11), 1188-1197. Wiley
Background The development of accurate, non‐invasive markers to diagnose and stage non‐alcoholic fatty liver disease (NAFLD) is critical to reduce the need for an invasive liver biopsy and to identify patients who are at the highest risk of hepat
Autor:
Trevor M. Penning, Laura Gathercole, Michael F. Saikali, Kratschmar Dv, Shelley Harris, Roger D. Cox, Ahmad Moolla, Jonathan Hazlehurst, Liz Bentley, Ryan C. Pink, Jeremy W. Tomlinson, Toryn Poolman, Nikolaos Nikolaou, Niall Dempster, Alex Odermatt, Claes Ohlsson, Matti Poutanen, Anastasia Arvaniti, Carolyn L. Cummins, Marijana Todorčević
BackgroundSteroid 5β-reductase (AKR1D1) plays important roles in hepatic glucocorticoid clearance and bile acid synthesis. Glucocorticoids and bile acids are potent metabolic regulators, but whether AKR1D1 controls metabolic phenotype in vivo is unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b696683522dd09fab5fd3b09f895111
https://doi.org/10.1101/2021.02.02.429227
https://doi.org/10.1101/2021.02.02.429227