Výsledky vyhledávání - "Ahmad M. Alqaisi"

Akademický článek

Identification of promising anti-EBOV inhibitors: de novo drug design, molecular docking and molecular dynamics studies

Autor: Eslam A. R. Mohamed, Sayed F. Abdelwahab, Ahmad M. Alqaisi, Amaal Mohammed Salih Nasr, Heba Ali Hassan

Publikováno v: Royal Society Open Science, Vol 9, Iss 9 (2022)

The Ebola virus (EBOV) outbreak was recorded as the largest in history and caused many fatalities. As seen in previous studies, drug repurposing and database filtration were the two major pathways to searching for potent compounds against EBOV. In th

Externí odkaz: https://doaj.org/article/fdb917252c934d0aabf28fbbcfb57c86

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In silico prediction of potential inhibitors for SARS-CoV-2 Omicron variant using molecular docking and dynamics simulation-based drug repurposing

Autor: Eslam A. R. Mohamed, Islam M. Abdel-Rahman, Magdi E. A. Zaki, Ahmad Al-Khdhairawi, Mahmoud M. Abdelhamid, Ahmad M. Alqaisi, Lyana binti Abd Rahim, Bilal Abu-Hussein, Azza A. K. El-Sheikh, Sayed F. Abdelwahab, Heba Ali Hassan

Publikováno v: Journal of Molecular Modeling. 29

Background In November 2021, variant B.1.1.529 of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified by the World Health Organization (WHO) and designated Omicron. Omicron is characterized by a high number of mutations, thirt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e19fc8df5226ead98b3c109b1a9ab1c
https://doi.org/10.1007/s00894-023-05457-z

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A Multistage In Silico Study of Natural Potential Inhibitors Targeting SARS-CoV-2 Main Protease

Autor: Eslam B. Elkaeed, Ibrahim H. Eissa, Hazem Elkady, Ahmed Abdelalim, Ahmad M. Alqaisi, Aisha A. Alsfouk, Alaa Elwan, Ahmed M. Metwaly

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8407

Among a group of 310 natural antiviral natural metabolites, our team identified three compounds as the most potent natural inhibitors against the SARS-CoV-2 main protease (PDB ID: 5R84), Mpro. The identified compounds are sattazolin and caprolactin A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab08340e4a0f74c6e8a6662b4968e883

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Molecular Dynamics Simulations of HLA-CW4-B2M-KIR2DL1 Protein and Homology Modeling of a Complex Associated with Psoriasis Disease (HLA-CW6-B2M-KIR2DS1)

Autor: Mansour H. Almatarneh, Ahmad M. Alqaisi, Enas K. Ibrahim, Ghada G. Kayed, Joshua W. Hollett

Molecular dynamics (MD) simulation was used to study the interactions of two immune proteins of HLA-Cw4-β2m-KIR2DL1 complex with small peptide QYDDAVYKL (nine amino acids) in an aqueous solution. This study aims to gain a detailed information about

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5302909b8d2a18a8310a1b6e56a90475
https://doi.org/10.1101/2021.12.20.473468

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