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pro vyhledávání: '"Ahmad Kiani Karanji"'
Autor:
Ahmad Kiani Karanji, James R. Arndt, Mahdiar Khakinejad, Maxmore Chaibva, Maryssa Beasley, Samaneh Ghassabi Kondalaji, Stephen J. Valentine, Justin Legleiter, Olivia Sarver
Publikováno v:
Biochemistry
Huntington’s disease (HD) is a genetic neurodegenerative disorder characterized by the formation of amyloid fibrils of the huntingtin protein (htt). The seventeen-residue N-terminal region of htt (Nt(17)) has been implicated in formation of early-p
Autor:
Ahmad Kiani Karanji, Chong Li, Kushani Attanayake, Sandra N. Majuta, Kinkini Udara Jayasundara, Peng Li, Nandhini Ranganathan, Stephen J. Valentine
Publikováno v:
Journal of the American Society for Mass Spectrometry. 30:1102-1114
Rapid, solution-phase hydrogen/deuterium exchange (HDX) coupled with mass spectrometry (MS) is demonstrated as a means for distinguishing small-molecule metabolites. HDX is achieved using capillary vibrating sharp-edge spray ionization (cVSSI) to all
Autor:
Mahdiar Khakinejad, Sandra N. Majuta, Ahmad Kiani Karanji, Kushani Attanayake, Samaneh Ghassabi Kondalaji, Stephen J. Valentine
Publikováno v:
Journal of the American Society for Mass Spectrometry. 29:2402-2412
The dominant gas-phase conformer of [M+3H]3+ ions of the model peptide acetyl-PSSSSKSSSSKSSSSKSSSSK has been examined with ion mobility spectrometry (IMS), gas-phase hydrogen deuterium exchange (HDX), and mass spectrometry (MS) techniques. The [M+3H]
Autor:
Stephen J. Valentine, Justin Legleiter, Daud Sharif, Ali Ranjbaran, Maryssa Beasley, Ahmad Kiani Karanji
Publikováno v:
J Mass Spectrom
The first 17 amino acid residues of Huntingtin protein (Nt17 of htt) are thought to play an important role in the protein’s function; Nt17 is one of two membrane binding domains in htt. In this study the binding ability of Nt17 peptide with vesicle
Autor:
Kushani Attanyake, Elinore Loch, Ahmad Kiani Karanji, Hossein Maleki, Stephen J. Valentine, Sandra N. Majuta
Publikováno v:
Current Opinion in Chemical Biology. 42:101-110
Ion mobility spectrometry – mass spectrometry (IMS-MS) provides information about the structures of gas-phase ions in the form of a collision cross section (CCS) with a neutral buffer gas. Indicating relative ion size, a CCS value alone is of limit
Publikováno v:
Russian Journal of Physical Chemistry A. 91:936-945
Fe3O4 magnetic nanoparticles (MNPs) were prepared by co-precipitation method. The nanoparticles were silica coated using TEOS, and then modified by the polymeric layers of polypropylene glycol (PPG) and polyethylene glycol (PEG). Finally, the core-sh
Autor:
Timothy Suder, Ahmad Kiani Karanji, Xiaojun Li, Ziyi He, Chong Li, Peng Li, Stephen J. Valentine, Nandhini Ranganathan
Publikováno v:
J Am Soc Mass Spectrom
Here, we report a continuous flow-based ionization method, capillary vibrating sharp-edge spray ionization (cVSSI), that nebulizes liquid sample directly at the outlet of a capillary without using high-speed nebulization gas or a high electrical fiel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63621d030621943756ad965a9e089ff
https://europepmc.org/articles/PMC6560627/
https://europepmc.org/articles/PMC6560627/
Publikováno v:
Journal of the American Society for Mass Spectrometry. 29(2)
Ion mobility spectrometry-mass spectrometry (IMS-MS) in combination with gas-phase hydrogen/deuterium exchange (HDX) and collision-induced dissociation (CID) is evaluated as an analytical method for small-molecule standard and mixture characterizatio