Zobrazeno 1 - 8
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pro vyhledávání: '"Ahmad H. Alammari"'
Publikováno v:
Canadian Journal of Physiology and Pharmacology.
Hydroxyeicosatetraenoic acids (HETEs) are hydroxylated arachidonic acid (AA) metabolites that are classified into midchain, subterminal, and terminal HETEs. Hydroxylation results in the formation of R and S enantiomers for each HETE, except for 20-HE
Publikováno v:
Prostaglandins & Other Lipid Mediators. 168:106749
Autor:
Sherif M. Shoieb, Ahmad H. Alammari, Jody Levasseur, Heidi Silver, Jason R. B. Dyck, Ayman O. S. El-Kadi
Publikováno v:
Journal of Cardiovascular Pharmacology. 79:833-845
Cytochrome P450 1B1 (CYP1B1) is known to be involved in the pathogenesis of several cardiovascular diseases, including cardiac hypertrophy and heart failure, through the formation of cardiotoxic metabolites named as mid-chain hydroxyeicosatetraenoic
Autor:
Fadumo Ahmed Isse, Ahmad H. Alammari, Ahmed A. El-Sherbeni, Dion R. Brocks, Ayman O.S. El-Kadi
Publikováno v:
Prostaglandinsother lipid mediators. 165
Arachidonic acid (AA) is a polyunsaturated fatty acid with a structure of 20:4(ω-6). Cytochrome P450s (CYPs) metabolize AA to several regioisomers and enantiomers of hydroxyeicosatetraenoic acids (HETEs). The hydroxy-metabolites (HETEs) exist as ena
Publikováno v:
Drug Metabolism and Disposition. :DMD-AR
Publikováno v:
Journal of pharmaceutical sciences. 109(7)
Cytochrome P450 1B1 (CYP1B1) has been reported to have a major role in metabolizing arachidonic acid (AA) into cardiotoxic metabolites, mid-chain hydroxyeicosatetraenoic acids (HETEs). Recently, we have shown that fluconazole decreases the level of m
Publikováno v:
The FASEB Journal. 33
Autor:
Ghada Abdelhamid, Erica McGinn, Ahmad H. Alammari, Doaa Dawood, Ahmed A. El-Sherbeni, Ayman O.S. El-Kadi, Zaid H. Maayah, Osama H. Elshenawy, Hassan N. Althurwi
Publikováno v:
Cardiovascular toxicology. 18(3)
Several studies have demonstrated the role of cytochrome P450 (CYP) and its associated arachidonic acid (AA) metabolites in the anthracyclines-induced cardiac toxicity. However, the ability of daunorubicin (DNR) to induce cardiotoxicity through the m