Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ahmad Essawy"'
Autor:
Seokwon Jo, Samantha Pritchard, Alicia Wong, Nandini Avula, Ahmad Essawy, John Hanover, Emilyn U. Alejandro
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Protein O-GlcNAcylation is a nutrient and stress-sensitive protein post-translational modification (PTM). The addition of an O-GlcNAc molecule to proteins is catalyzed by O-GlcNAc transferase (OGT), whereas O-GlcNAcase (OGA) enzyme is responsible for
Externí odkaz:
https://doaj.org/article/c526a5a84dea408e9ce3e1b64026f57d
Autor:
Emilyn U. Alejandro, Eric Gustafson, Ahmad Essawy, Neha Panigrahy, Regina Schlichting, Nicholas Esch, Ramkumar Mohan, Amber Lockridge, Seokwon Jo, Ada Admin
Protein translation is essential for cell physiology, and dysregulation of this process has been linked to aging-related diseases such as type 2 diabetes. Reduced protein level of a requisite scaffolding protein of the initiation complex, eIF4G1, dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cceadce74dfc93e42cc0dd51ccf4bec7
https://doi.org/10.2337/figshare.13110335.v1
https://doi.org/10.2337/figshare.13110335.v1
Autor:
Megan M Beetch, Ahmad Essawy, Emilyn U. Alejandro, Eric C. Gustafson, Amber D Lockridge, Seokwon Jo
Publikováno v:
The Journal of Biological Chemistry
The nutrient sensor O-GlcNAc transferase (OGT) catalyzes posttranslational addition of O-GlcNAc onto target proteins, influencing signaling pathways in response to cellular nutrient levels. OGT is highly expressed in pancreatic glucagon-secreting cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85c264e396a1d78c0ec160f5f38f8c7
https://pubmed.ncbi.nlm.nih.gov/33460647
https://pubmed.ncbi.nlm.nih.gov/33460647
Autor:
Eric C. Gustafson, Regina Schlichting, Amber D Lockridge, Seokwon Jo, Nicholas Esch, Neha Panigrahy, Ramkumar Mohan, Ahmad Essawy, Emilyn U. Alejandro
Publikováno v:
Diabetes
Protein translation is essential for cell physiology, and dysregulation of this process has been linked to aging-related diseases such as type 2 diabetes. Reduced protein level of a requisite scaffolding protein of the initiation complex, eIF4G1, dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2895145131aaae287aaff661f488c271
https://pubmed.ncbi.nlm.nih.gov/33115825
https://pubmed.ncbi.nlm.nih.gov/33115825
Autor:
Peter Nash, Meri T. Firpo, Ahmad Essawy, Kristin J. Voltzke, Klearchos K. Papas, Bradley P. Weegman, Marjan Jahani, Zhaohui Geng, Alexandra L. Carlson, Benjamin B. Becker
Publikováno v:
Journal of Visualized Experiments.
In this demonstration, spheroids formed from the β-TC6 insulinoma cell line were cultured as a model of manufacturing a mammalian islet cell product to demonstrate how regulating nutrient levels can improve cell yields. In previous studies, bioreact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5d0c05841871e99505aef53bcb7a33
https://doi.org/10.3791/52224
https://doi.org/10.3791/52224
Autor:
Jo, Seokwon, Lockridge, Amber, Mohan, Ramkumar, Esch, Nicholas, Schlichting, Regina, Panigrahy, Neha, Essawy, Ahmad, Gustafson, Eric, Alejandro, Emilyn U.
Publikováno v:
Diabetes; Jan2021, Vol. 70 Issue 1, p155-170, 16p