Structural basis of the mispairing of an artificially expanded genetic information system

Autor: Lucy P. Eperon, Nicholas M. Burton, Christopher R. Agnew, Ian C. Eperon, Sara De Ornellas, R. Leo Brady, Glenn A. Burley, Linus F. Reichenbach, Nathan R. Zaccai, Ahmad Ahmad Sobri

Publikováno v: Chem
Reichenbach, L F, Sobri, A A, Zaccai, N R, Agnew, C, Burton, N, Eperon, L P, de Ornellas, S, Eperon, I C, Brady, R L & Burley, G A 2016, ' Structural Basis of the Mispairing of an Artificially Expanded Genetic Information System ', Chem, vol. 1, no. 6, pp. 946-958 . https://doi.org/10.1016/j.chempr.2016.11.009

Summary Relative to naturally occurring Watson-Crick base pairs, the synthetic nucleotide P pairs with Z within DNA duplexes through a unique hydrogen-bond arrangement. The loss of this synthetic genetic information by PCR results in the conversion o

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https://strathprints.strath.ac.uk/59073/1/Reichenbach_etal_Chem_2016_Structural_basis_of_the_mispairing_of_an_artificially.pdf