Somatic Mosaicism of a PDGFRB Activating Variant in Aneurysms of the Intracranial, Coronary, Aortic, and Radial Artery Vascular Beds

Autor: Carolina A. Parada, Fatima M. El‐Ghazali, Daphne Toglia, Jacob Ruzevick, Malia McAvoy, Samuel Emerson, Yigit Karasozen, Tina Busald, Ahmad A. Nazem, Shaun M. Suranowitz, Sherene Shalhub, Desiree A. Marshall, Luis F. Gonzalez‐Cuyar, Michael O. Dorschner, Manuel Ferreira

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 4 (2022)

Background Activating variants in platelet‐derived growth factor receptor beta (PDGFRB), including a variant we have previously described (p.Tyr562Cys [g.149505130T>C [GRCh37/hg19]; c.1685A>G]), are associated with development of multiorgan patholo

Externí odkaz: https://doaj.org/article/0b0ae9f195bf4bbdaa20dfe1f68609b7

Featured Article: Nanoenhanced matrix metalloproteinase-responsive delivery vehicles for disease resolution and imaging

Autor: Ryan R. Clark, María del Pilar Sosa Idelchik, Ahmad A Nazem, Nicole L Shakerley, Donald A McCarthy, James McNeilan, Mehmet V. Yigit, J. Andres Melendez

Publikováno v: Experimental Biology and Medicine. 241:2023-2032

The wide array of proteases, including matrix metalloproteinases, produced in response to many pathogenic insults, confers a unique proteolytic signature which is often disease specific and provides a potential therapeutic target for drug delivery. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8b5d578fcc2ab30a571f42f4ecd17c
https://doi.org/10.1177/1535370216662534

Anomalous right coronary artery managed with bypass and proximal ligation.

Autor: Ramcharran H; Department of Cardiothoracic Surgery, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY, 13210, USA. ramcharh@upstate.edu., Nazem A; Department of Cardiothoracic Surgery, St. Joseph's Hospital, Syracuse, NY, USA.

Publikováno v: Journal of cardiothoracic surgery [J Cardiothorac Surg] 2024 Jul 13; Vol. 19 (1), pp. 439. Date of Electronic Publication: 2024 Jul 13.

Isocratic reporter-exclusion immunoassay using restricted-access adsorbents.

Autor: Dhamane S; Department of Biology and Biochemistry, University of Houston, Houston, TX, USA. willson@uh.edu., Patil U; Department of Biology and Biochemistry, University of Houston, Houston, TX, USA. willson@uh.edu., Smith M; Department of Chemical and Biomolecular Engineering, University of Houston, TX, USA., Adhikari M; Department of Biology and Biochemistry, University of Houston, Houston, TX, USA. willson@uh.edu., Nazem A; Department of Biomedical Engineering, University of Houston, Houston, TX, USA., Conrad JC; Department of Chemical and Biomolecular Engineering, University of Houston, TX, USA., Kourentzi K; Department of Chemical and Biomolecular Engineering, University of Houston, TX, USA., Willson RC; Department of Biology and Biochemistry, University of Houston, Houston, TX, USA. willson@uh.edu and Department of Chemical and Biomolecular Engineering, University of Houston, TX, USA and Department of Biomedical Engineering, University of Houston, Houston, TX, USA and Escuela de Medicina y Ciencias de las Salud ITESM, Monterrey, Mexico.

Publikováno v: The Analyst [Analyst] 2021 Aug 07; Vol. 146 (15), pp. 4835-4840. Date of Electronic Publication: 2021 Jul 02.