Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ahlem, Essakly"'
Autor:
Ahlem Essakly, Heike Loeser, Max Kraemer, Hakan Alakus, Seung-Hun Chon, Thomas Zander, Reinhard Buettner, Axel M. Hillmer, Christiane J. Bruns, Wolfgang Schroeder, Florian Gebauer, Alexander Quaas
Publikováno v:
Translational Oncology, Vol 13, Iss 2, Pp 157-164 (2020)
Gene amplifications of PIK3CA or KRAS induce a downstream activation of the AKT-mTOR or RAF-ERK-pathways. Interactions of the active AKT pathway have been implicated in the inflammatory tumor microenvironment. Nothing is known about these interaction
Externí odkaz:
https://doaj.org/article/db623cc2141149aa879ebba56e8f3297
Autor:
Simon Schallenberg, Julian Bork, Ahlem Essakly, Hakan Alakus, Reinhard Buettner, Axel M. Hillmer, Christiane Bruns, Wolfgang Schroeder, Thomas Zander, Heike Loeser, Florian Gebauer, Alexander Quaas
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background The SWI/SNF complex is an important chromatin remodeler, commonly dysregulated in cancer, with an estimated mutation frequency of 20%. ARID1A is the most frequently mutated subunit gene. Almost nothing is known about the other fam
Externí odkaz:
https://doaj.org/article/e10e4a042e8d4a9caa143e89f259d80d
Autor:
Hanene Landolsi, Moncef Mokni, Sihem Hmissa, Sarra Mestiri, Ahlem Essakly, Nabiha Missaoui, Nihed Abdessayed, Mohamed Tahar Yacoubi
Publikováno v:
Pathology - Research and Practice. 215:446-452
Hydatidiform moles (HM) are characterized by an abnormal proliferating trophoblast with a potential for a malignant transformation. Similar to other human tumors, trophoblastic pathogenesis is likely a multistep process involving several molecular an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae1c063b55b0eb25001bf0e9437fbbbb
https://doi.org/10.1016/j.prp.2018.12.015
https://doi.org/10.1016/j.prp.2018.12.015
Autor:
Christiane J. Bruns, Thomas Zander, Heike Loeser, Alexander Damanakis, Hans F. Fuchs, Ahlem Essakly, Wolfgang Schröder, Alexander Quaas, Matthias Scholz, Reinhard Büttner, Florian Gebauer
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Valid biomarkers for a better prognostic prediction of the clinical course in esophageal adenocarcinoma (EAC) are still not implemented. Integrin alpha V (ITGAV), a transmembrane glycoprotein responsible for cell-to-matrix binding has been found to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2b7c2db284ce1f09084c46781b8128
https://doi.org/10.1038/s41598-020-75085-7
https://doi.org/10.1038/s41598-020-75085-7
Autor:
Axel M. Hillmer, Florian Gebauer, Hakan Alakus, Ahlem Essakly, Alexander Quaas, Reinhard Buettner, Simon Schallenberg, Wolfgang Schroeder, Julian Bork, Heike Loeser, Thomas Zander, Christiane J. Bruns
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
BackgroundThe SWI/SNF complex is an important chromatin remodeler, commonly dysregulated in cancer, with an estimated mutation frequency of 20%. ARID1A is the most frequently mutated subunit gene. Almost nothing is known about the other familiar memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eef6a13ed01ab5ea82345c8efd8cbe9
https://doi.org/10.1186/s12885-019-6425-3
https://doi.org/10.1186/s12885-019-6425-3
Autor:
Wolfgang Schroeder, Max Kraemer, Alexander Quaas, Ahlem Essakly, Christiane Bruns, Thomas Zander, Axel M. Hillmer, Heike Loeser, Seung-Hun Chon, Florian Gebauer, Reinhard Buettner, Hakan Alakus
Publikováno v:
Translational Oncology
Translational Oncology, Vol 13, Iss 2, Pp 157-164 (2020)
Translational Oncology, Vol 13, Iss 2, Pp 157-164 (2020)
Gene amplifications of PIK3CA or KRAS induce a downstream activation of the AKT-mTOR or RAF-ERK-pathways. Interactions of the active AKT pathway have been implicated in the inflammatory tumor microenvironment. Nothing is known about these interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea8641796ca3e10956adf0dc78c377a
https://pubmed.ncbi.nlm.nih.gov/31865178
https://pubmed.ncbi.nlm.nih.gov/31865178
Autor:
Martin K. H. Maus, Heike Loeser, Ahlem Essakly, Reinhard Büttner, Florian Gebauer, Alexander Quaas, Alexander Damanakis, Lars Schiffmann, Lars Tharun, Wolfgang Schröder, Christiane J. Bruns, Yue Zhao, Hans F. Fuchs, Thomas Zander, Anne Sophie Jacob
Publikováno v:
Cancers
Cancers, Vol 12, Iss 2, p 451 (2020)
Volume 12
Issue 2
Cancers, Vol 12, Iss 2, p 451 (2020)
Volume 12
Issue 2
Dickkopf-2 (DKK2) has been described as Wnt/beta-catenin pathway antagonist and its expression is mediated by micro RNA-221 (miRNA-221). So far, there is only limited data characterizing the role of DKK2 expression in esophageal cancer. A tissue micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a0c0e3dfda640d075a4296527ce5a4
https://doi.org/10.3390/cancers12020451
https://doi.org/10.3390/cancers12020451
Autor:
Nabiha, Missaoui, Hanene, Landolsi, Sarra, Mestiri, Ahlem, Essakly, Nihed, Abdessayed, Sihem, Hmissa, Moncef, Mokni, Mohamed Tahar, Yacoubi
Publikováno v:
Pathology, research and practice. 215(3)
Hydatidiform moles (HM) are characterized by an abnormal proliferating trophoblast with a potential for a malignant transformation. Similar to other human tumors, trophoblastic pathogenesis is likely a multistep process involving several molecular an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c09b0f8b019a05e4cc12479d6fb7552
https://pubmed.ncbi.nlm.nih.gov/30558966
https://pubmed.ncbi.nlm.nih.gov/30558966