Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ahlame Saidi"'
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 810 (2023)
Mucopolysaccharidosis (MPS) consists of a group of inherited lysosomal storage disorders that are caused by a defect of certain enzymes that participate in the metabolism of glycosaminoglycans (GAGs). The abnormal accumulation of GAGs leads to progre
Externí odkaz:
https://doaj.org/article/bbae1135c92c4de1908d23af76fd7a7f
Autor:
Paul Bigot, Simon Chesseron, Ahlame Saidi, Damien Sizaret, Christelle Parent, Agnès Petit-Courty, Yves Courty, Fabien Lecaille, Gilles Lalmanach
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 5 (2022)
Background. Chronic obstructive pulmonary disease (COPD) is an irreversible disease mainly caused by smoking. COPD is characterized by emphysema and chronic bronchitis associated with enhanced epithelial permeability. Hypothesis. Lung biopsies from s
Externí odkaz:
https://doaj.org/article/f3d8ae9e4fdd44c4804add58d83ff438
Autor:
Gilles Lalmanach, Ahlame Saidi, Paul Bigot, Thibault Chazeirat, Fabien Lecaille, Mylène Wartenberg
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 1944 (2020)
Besides their primary involvement in the recycling and degradation of proteins in endo-lysosomal compartments and also in specialized biological functions, cysteine cathepsins are pivotal proteolytic contributors of various deleterious diseases. Whil
Externí odkaz:
https://doaj.org/article/6c7b4a393cfe4a20aea2f64def0236b0
Autor:
Vincent Aucagne, Mylène Wartenberg, Gilles Lalmanach, Jean-Baptiste Madinier, Seda Seren, Fabien Lecaille, Guy Ilango, Ahlame Saidi, Brice Korkmaz
Publikováno v:
Bioconjugate Chemistry
Bioconjugate Chemistry, 2021, 32 (8), pp.1782-1790. ⟨10.1021/acs.bioconjchem.1c00267⟩
Bioconjugate Chemistry, 2021, 32 (8), pp.1782-1790. ⟨10.1021/acs.bioconjchem.1c00267⟩
International audience; A near-infrared fluorescent (NIRF) substrate-based probe (SBP) was conceived to monitor secreted human proteinase 3 (hPR3) activity. This probe, called pro3-SBP, is shaped by a fused peptide hairpin loop structure, which assoc
Autor:
Sophie Denamur, Thibault Chazeirat, Martyna Maszota-Zieleniak, Romain R. Vivès, Ahlame Saidi, Fuming Zhang, Robert J. Linhardt, François Labarthe, Sergey A. Samsonov, Gilles Lalmanach, Fabien Lecaille
Publikováno v:
Carbohydrate Polymers
Carbohydrate Polymers, 2022, 293, pp.119734. ⟨10.1016/j.carbpol.2022.119734⟩
Carbohydrate Polymers, 2022, 293, pp.119734. ⟨10.1016/j.carbpol.2022.119734⟩
Mucopolysaccharidoses (MPS) are a group of rare lysosomal storage diseases characterized by glycosaminoglycan (GAG) accumulation causing progressive multi-organs dysfunction and ultimately severe cardio-respiratory damages. Human cystatin C (hCC), a
Publikováno v:
Rare Disease and Orphan Drugs Journal. 2:3
Lymphangioleiomyomatosis (LAM) is a rare disease which is characterized by cystic lung destruction and lymphangiomas, and is associated with a high risk of osteoporosis-related bone fractures. Its diagnosis is based on pulmonary anatomopathological c
Publikováno v:
Molecular aspects of medicine. 88
Human cysteine cathepsins form a family of eleven proteases (B, C, F, H, K, L, O, S, V, W, X/Z) that play important roles in a considerable number of biological and pathophysiological processes. Among them, cathepsin V, also known as cathepsin L2, is
Autor:
Gilles Lalmanach, Geneviève Fort, Pauline Gaboriaud, Lise Vanderlynden, Edouard Guitton, Catherine Schouler, Pauline Vettori, Fabien Lecaille, Françoise I. Bussière, Aurélie Fessard, Anne-Christine Lalmanach, Ahlame Saidi, Rodrigo Guabiraba, Fabrice Laurent
Publikováno v:
Research in Veterinary Science
Research in Veterinary Science, Elsevier, 2021, 140, pp.109-116. ⟨10.1016/j.rvsc.2021.08.013⟩
Research in Veterinary Science, Elsevier, 2021, 140, pp.109-116. ⟨10.1016/j.rvsc.2021.08.013⟩
International audience; Coccidiosis is a disease caused by Eimeria, which represents the first parasitic disease in poultry farming. Among them, E. tenella is a virulent species which specifically colonizes the caecum. The inflammatory response to in
Autor:
Pierre-Marie Andrault, Sergey A. Samsonov, Sophie Denamur, Krzysztof K. Bojarski, Fuming Zhang, Ahlame Saidi, Fabien Lecaille, Dieter Brömme, M. Tardieu, François Labarthe, Thibault Chazeirat, Robert J. Linhardt, Gilles Lalmanach, Damien Sizaret
Publikováno v:
Carbohydrate Polymers
Carbohydrate Polymers, 2021, 253, pp.117261-. ⟨10.1016/j.carbpol.2020.117261⟩
Carbohydrate Polymers, Elsevier, 2021, 253, pp.117261-. ⟨10.1016/j.carbpol.2020.117261⟩
Carbohydrate Polymers, 2021, 253, pp.117261-. ⟨10.1016/j.carbpol.2020.117261⟩
Carbohydrate Polymers, Elsevier, 2021, 253, pp.117261-. ⟨10.1016/j.carbpol.2020.117261⟩
International audience; Mucopolysaccharidosis (MPS) are rare inherited diseases characterized by accumulation of lysosomal glycosaminoglycans, including heparan sulfate (HS). Patients exhibit progressive multi-visceral dysfunction and shortened lifes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1bff7eccfa616a990c6345ac9050d4
https://hal.science/hal-03493189
https://hal.science/hal-03493189
Autor:
Lydie Nadal-Desbarats, Pierre-Marie Andrault, Gilles Lalmanach, Ahlame Saidi, Paul Bigot, Mylène Wartenberg, Fabien Lecaille
Publikováno v:
Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2020, 150, pp.53-65. ⟨10.1016/j.freeradbiomed.2020.02.013⟩
Free Radical Biology and Medicine, Elsevier, 2020, 150, pp.53-65. ⟨10.1016/j.freeradbiomed.2020.02.013⟩
International audience; Lung cysteine cathepsin S (CatS) that is a potent elastase plays a deleterious role in alveolar remodeling during smoke-induced emphysema. Despite the presence of a reactive nucleophilic cysteine (Cys25) within its active site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ee722b0e527abc3c86ea7d05e86889
https://hal.archives-ouvertes.fr/hal-03677268
https://hal.archives-ouvertes.fr/hal-03677268