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pro vyhledávání: '"Ahlam S. Altowairqi"'
Autor:
Mona Alsolami, Doaa Aboalola, Dolal Malibari, Tariq Alghamdi, Walaa Alshekhi, Hind Jad, Rea Rumbold-Hall, Ahlam S. Altowairqi, Sandra M. Bell, Rawiah Abdullah Alsiary
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The MCPH1 gene, also known as BRCT-repeat inhibitor of hTERT expression (BRIT1), has three BRCA1 carboxyl-terminal domains which is an important regulator of DNA repair, cell cycle checkpoints and chromosome condensation. MCPH1/BRIT1 is also known as
Externí odkaz:
https://doaj.org/article/4fb8bac4ca0f4db598a9dcfc5bc70fba
Publikováno v:
Advances in Breast Cancer Research. 10:60-74
Objective: PIK3CA is the most common pathway affected by mutations in breast cancer. PIK3CA/PTEN pathway is under intense investigation as a possible target for molecular therapy. Dysregulation PIK3CA/PTEN pathway is a substantial mechanism for the d