Výsledky vyhledávání - "Ahlam I. Salameh"

Akademický článek

Effects of extracellular metabolic acidosis and out-of-equilibrium CO2/HCO3− solutions on intracellular pH in cultured rat hippocampal neurons

Autor: Patrice G. Bouyer, Ahlam I. Salameh, Yuehan Zhou, Tiffany N. Kolba, Walter F. Boron

Publikováno v: Frontiers in Physiology, Vol 15 (2024)

Metabolic acidosis (MAc)—an extracellular pH (pHo) decrease caused by a [HCO3−]o decrease at constant [CO2]o—usually causes intracellular pH (pHi) to fall. Here we determine the extent to which the pHi decrease depends on the pHo decrease vs th

Externí odkaz: https://doaj.org/article/2a62928045b4444992ceda97ed66d00a

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Akademický článek

Soluble prion protein and its N-terminal fragment prevent impairment of synaptic plasticity by Aβ oligomers: Implications for novel therapeutic strategy in Alzheimer's disease

Autor: Jonah J. Scott-McKean, Krystyna Surewicz, Jin-Kyu Choi, Vernon A. Ruffin, Ahlam I. Salameh, Krzysztof Nieznanski, Alberto C.S. Costa, Witold K. Surewicz

Publikováno v: Neurobiology of Disease, Vol 91, Iss , Pp 124-131 (2016)

The pathogenic process in Alzheimer's disease (AD) appears to be closely linked to the neurotoxic action of amyloid-β (Aβ) oligomers. Recent studies have shown that these oligomers bind with high affinity to the membrane-anchored cellular prion pro

Externí odkaz: https://doaj.org/article/af5552d344b44fee9ff49de3a1136663

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Akademický článek

Intracellular pH regulation by acid/base transporters in mammalian neurons

Autor: Vernon A. Ruffin, Ahlam I. Salameh, Walter F. Boron, Mark D. Parker

Publikováno v: Frontiers in Physiology, Vol 5 (2014)

Intracellular pH (pHi) regulation in the brain is important in both physiological and physiopathological conditions because changes in pHi generally result in altered neuronal excitability. In this review, we will cover 4 major areas: [1] The effect

Externí odkaz: https://doaj.org/article/d72fad96fda44c0fa51b23bc05aa83ab

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MEP-ART: A system for real-time feedback and analysis of transcranial magnetic stimulation motor evoked potentials

Autor: Margaret Skelly, Jessica McCabe, Svetlana Pundik, Ahlam I. Salameh

Publikováno v: Brain Stimulation, Vol 13, Iss 6, Pp 1614-1616 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea21cade458a01c580009e8327a35926
http://www.sciencedirect.com/science/article/pii/S1935861X20302515

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Role of channels in the oxygen permeability of red blood cells

Autor: Rossana Occhipinti, Fraser J. Moss, Dale Huffman, Amanda B. Wass, Pan Zhao, R. Ryan Geyer, Ahlam I. Salameh, Howard J. Meyerson, Gerolf Gros, Sara Taki, Walter F. Boron

Many have believed that oxygen (O2) crosses red blood cell (RBC) membranes by dissolving in lipids that offer no resistance to diffusion. However, using stopped-flow (SF) analyses of hemoglobin (Hb) absorbance spectra during O2off-loading from mouse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bbee6ec63edb3b71e525ec434cb435b9
https://doi.org/10.1101/2020.08.28.265066

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Abstract TP152: Sensory Function Improvement is Related to White Matter Changes During Rehabilitation

Autor: Jessica McCabe, Margaret Skelly, Soha Sadeghikhah, Svetlana Pundik, Ahlam I. Salameh

Publikováno v: Stroke. 51

Objective: Structural changes related to recovery of sensory function are not well understood. Previously, we demonstrated a relationship between improved sensory function and increased cortical thickness in ipsilesional occipitoparietal and contrale

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9c0357ba23c418d583ac2318434a322
https://doi.org/10.1161/str.51.suppl_1.tp152

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Role of Cl−-HCO3−exchanger AE3 in intracellular pH homeostasis in cultured murine hippocampal neurons, and in crosstalk to adjacent astrocytes

Autor: Walter F. Boron, Christian A. Hübner, Ahlam I. Salameh

Publikováno v: The Journal of Physiology. 595:93-124

KEY POINTS A polymorphism of human AE3 is associated with idiopathic generalized epilepsy. Knockout of AE3 in mice lowers the threshold for triggering epileptic seizures. The explanations for these effects are elusive. Comparisons of cells from wild-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f80c688bc2f6076bf3955376d5aeb4e
https://doi.org/10.1113/jp272470

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Soluble prion protein and its N-terminal fragment prevent impairment of synaptic plasticity by Aβ oligomers: Implications for novel therapeutic strategy in Alzheimer's disease

Autor: Krystyna Surewicz, Krzysztof Nieznanski, Vernon A. Ruffin, Ahlam I. Salameh, Jonah J. Scott-McKean, Jin-Kyu Choi, Alberto C.S. Costa, Witold K. Surewicz

Publikováno v: Neurobiology of Disease, Vol 91, Iss, Pp 124-131 (2016)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfa34ad3f5a470e56e327e939258b72
https://doi.org/10.1016/j.nbd.2016.03.001

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Effects of metabolic acidosis on intracellular pH responses in multiple cell types

Autor: Vernon A. Ruffin, Walter F. Boron, Ahlam I. Salameh

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 307:R1413-R1427

Metabolic acidosis (MAc), a decrease in extracellular pH (pHo) caused by a decrease in [HCO3−]oat a fixed [CO2]o, is a common clinical condition and causes intracellular pH (pHi) to fall. Although previous work has suggested that MAc-induced decrea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64b4de49295ce9c881346aa5105ab00
https://doi.org/10.1152/ajpregu.00154.2014

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