Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ahhyun Kim"'
Autor:
Ahhyun Kim, Claudia A. Benavente
Publikováno v:
Epigenomes, Vol 8, Iss 3, p 26 (2024)
Ubiquitin-like with PHD and RING finger domains 1 (UHRF1) is an essential protein involved in the maintenance of repressive epigenetic marks, ensuring epigenetic stability and fidelity. As an epigenetic regulator, UHRF1 comprises several functional d
Externí odkaz:
https://doaj.org/article/732cf8512ce34b9884ec63803a2a900c
Autor:
Stephanie C. Wu, Ahhyun Kim, Yijun Gu, Daniel I. Martinez, Loredana Zocchi, Claire C. Chen, Jocelyne Lopez, Kelsey Salcido, Sarah Singh, Jie Wu, Ali Nael, Claudia A. Benavente
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
Abstract Loss-of-function mutations at the retinoblastoma (RB1) gene are associated with increased mortality, metastasis, and poor therapeutic outcome in several cancers, including osteosarcoma. However, the mechanism(s) through which RB1 loss worsen
Externí odkaz:
https://doaj.org/article/03dd0841ee8948ffa1fd264bf58aa27d
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The protein kinase ATR is activated at sites of DNA double-strand breaks where it plays important roles in promoting DNA end resection and regulating cell cycle progression. TOPBP1 is a multi BRCT repeat containing protein that activates ATR
Externí odkaz:
https://doaj.org/article/8c802708d8794d5294da91ea9152b9c8
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
The protein kinase ATR is activated at sites of DNA double-strand breaks where it plays important roles in promoting DNA end resection and regulating cell cycle progression. TOPBP1 is a multi BRCT repeat containing protein that activates ATR at DSBs.
Autor:
Ahhyun Kim, Claire Chen, Loredana Zocchi, Claudia A. Benavente, Jocelyne Lopez, Stephanie C. Wu, Jie Wu, Kelsey Salcido
Loss of function mutations at the retinoblastoma (RB1) gene are associated with increased mortality, metastasis and poor therapeutic outcome in several cancers, including osteosarcoma (OS). However, the mechanism(s) through whichRB1loss worsens clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d28e523cd61079a56c5b861f6c7779b
https://doi.org/10.1101/2020.05.24.113647
https://doi.org/10.1101/2020.05.24.113647
Autor:
Ahhyun Kim, Quinn Cowan, Kenna Ruis, Holly Senebandith, Katrina Montales, W. Matthew Michael, Hovik J. Gasparyan
Publikováno v:
DNA Repair (Amst)
TOPBP1 is an important scaffold protein that helps orchestrate the cellular response to DNA damage. Although it has been previously appreciated that TOPBP1 can form oligomers, how this occurs and the functional consequences for oligomerization were n
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(20)
Hamacanthins are a class of antibacterial bisindole alkaloids isolated from marine sponges. Based on structure-activity relationships and in silico MRSA PK binding analysis of these bisindole alkaloids, the authors designed new hamacanthin B derivati
Publikováno v:
International Journal of Quantum Chemistry. 117:e25341
Coupling between iso(thio)cyanates and amines, alcohols, and thiols to yield (thio)urea/urethane in the gas phase is important for the vacuum deposition processes of functional organic thin films such as molecular layer deposition or chemical vapor d
Publikováno v:
Annals of Laboratory Medicine
Hereditary elliptocytosis (HE) is a group of disorders characterized by abnormal erythrocyte shapes that occur mainly in individuals of African and Mediterranean ancestry. In Korea, HE is the cause of 1.4% (6/431) cases of hereditary hemolytic anemia
Autor:
Eun-Jee Oh, Yonggoo Kim, Myungshin Kim, Jihyang Lim, Ahhyun Kim, Kyungja Han, Joonhong Park, Yeon-Joon Park
Publikováno v:
Annals of Laboratory Medicine
Background The reticulocyte count is a good marker of erythropoietic activity of the bone marrow. In the mid-1990s, automated flow cytometric analysis replaced microscopy for the quantification of reticulocytes. Leukocytosis cases with an erroneously