Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Aharon, Rabinkov"'
Autor:
María Pérez-Mato, Antonio Dopico-López, Yunus Akkoc, Sonia López-Amoedo, Clara Correa-Paz, María Candamo-Lourido, Ramón Iglesias-Rey, Esteban López-Arias, Ana Bugallo-Casal, Andrés da Silva-Candal, Susana B. Bravo, María del Pilar Chantada-Vázquez, Susana Arias, María Santamaría-Cadavid, Ana Estany-Gestal, Ahlem Zaghmi, Marc A. Gauthier, María Gutiérrez-Fernández, Abraham Martin, Jordi Llop, Cristina Rodríguez, Ángeles Almeida, Martina Migliavacca, Ester Polo, Beatriz Pelaz, Devrim Gozuacik, Naouale El Yamani, Tanima SenGupta, Elise Rundén-Pran, José Vivancos, Mar Castellanos, Exuperio Díez-Tejedor, Tomás Sobrino, Aharon Rabinkov, David Mirelman, José Castillo, Francisco Campos
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111108- (2024)
Summary: The blood enzyme glutamate-oxaloacetate transaminase (GOT) has been postulated as an effective therapeutic to protect the brain during stroke. To demonstrate its potential clinical utility, a new human recombinant form of GOT (rGOT) was prod
Externí odkaz:
https://doaj.org/article/6d8f45238537419f8ea4fc14759d7f22
Autor:
Ramón Iglesias-Rey, Andrés da Silva-Candal, María Pérez-Mato, David Mirelman, Antonio Dopico-López, Francisco Campos, José Castillo, Tomás Sobrino, Aharon Rabinkov, Ana Bugallo-Casal
Publikováno v:
Translational Research. 230:68-81
Glutamate oxaloacetate transaminase 1 (GOT1) enzyme plays a critical role in the cell metabolism by participating in the carbohydrate and amino acid metabolism. In ischemic stroke, we have demonstrated that recombinant GOT1 acts as a novel neuroprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25931e6f44480e50bf4b7633d7eee0a1
https://doi.org/10.1016/j.trsl.2020.10.004
https://doi.org/10.1016/j.trsl.2020.10.004
Autor:
Ronny Peri-Naor, Zohar Pode, Aharon Rabinkov, Naama Lahav-Mankovski, David Margulies, Leila Motiei
Publikováno v:
Journal of the American Chemical Society. 142(37)
A method for generating targeted, pattern-generating, protein surface sensors via the self-assembly of modified oligodeoxynucleotides (ODNs) is described. The simplicity by which these systems can be created enabled the development of a sensor that c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93e15d1ac8e189d0c2db1efba0c7bca
https://pubmed.ncbi.nlm.nih.gov/32786755
https://pubmed.ncbi.nlm.nih.gov/32786755
Publikováno v:
Journal of Pharmacy and Pharmacology. 6
Objectives: Alliinase is a pyridoxal-5’-phosphate (PLP)-dependent enzyme responsible for the production of diallyl thiosulfinate (allicin), the biologically active component of garlic, from alliin. The use of allicin for treatment of various diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b52bdb85a3a650b75d3e78ace68d4e8a
https://doi.org/10.17265/2328-2150/2018.05.001
https://doi.org/10.17265/2328-2150/2018.05.001
Publikováno v:
J Clin Hypertens (Greenwich)
J Clin Hypertens (Greenwich). 2010;12:451–455. ©2010 Wiley Periodicals, Inc. S-allyl-mercapto-captopril (CPSSA) is a conjugate of captopril with allicin, an active principle in garlic with multiple beneficial actions on metabolic syndrome abnormal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155e3cf1321251416a045439ce09f544
https://doi.org/10.1111/j.1751-7176.2010.00270.x
https://doi.org/10.1111/j.1751-7176.2010.00270.x
Autor:
Menachem Rubinstein, Aharon Rabinkov, Soohyun Kim, Daniela Novick, Tania Azam, Charles A. Dinarello
Publikováno v:
Proceedings of the National Academy of Sciences. 103:3316-3321
IL-32, a recently discovered proinflammatory cytokine with four isoforms, induces IL-1beta, TNF-alpha, IL-6, and chemokines. Here, we used ligand (IL-32alpha) affinity chromatography in an attempt to isolate an IL-32alpha soluble receptor or binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9fd2f6d41efb4d5ee323a92ae3d54ed
https://doi.org/10.1073/pnas.0511206103
https://doi.org/10.1073/pnas.0511206103
Autor:
Fabian D. Arditti, Aharon Rabinkov, Talia Miron, Yair Reisner, Alain Berrebi, Meir Wilchek, David Mirelman
Publikováno v:
Molecular Cancer Therapeutics. 4:325-332
Allicin, a highly active component from freshly crushed garlic, is produced upon the reaction of the small molecular weight molecule alliin, with the enzyme alliinase (EC 4.4.1.4). Because allicin was shown to be toxic to various mammalian cells in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43445b8ae69173ec2d5967f4c3185531
https://doi.org/10.1158/1535-7163.325.4.2
https://doi.org/10.1158/1535-7163.325.4.2
Autor:
Aviv Shaish, Esfir Ulman, Talia Miron, Ayelet Gonen, Hana Levkovitz, Lev Weiner, Dikla Ben-Shushan, David Mirelman, Aharon Rabinkov, Dror Harats, Meir Wilchek
Publikováno v:
Pathobiology. 72:325-334
Objective: Garlic (Allium sativum) has been suggested to affect several cardiovascular risk factors. Its antiatherosclerotic properties are mainly attributed to allicin that is produced upon crushing of the garlic clove. Most previous studies used va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752ea6d023450e868d85d50d336cc7a2
https://doi.org/10.1159/000091330
https://doi.org/10.1159/000091330
Publikováno v:
Analytical Biochemistry. 331:364-369
Allicin (diallylthiosulfinate), the active substance of garlic, has been shown to possess a variety of biological activities. Mechanistic and pharmacokinetic studies of allicin and its derivatives raise the need for a labeled compound. However, label
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85023594cd11df1d8d3e3f74a0f02eaa
https://doi.org/10.1016/j.ab.2004.03.054
https://doi.org/10.1016/j.ab.2004.03.054
Autor:
Alexander Brill, Rami Hershkoviz, Talia Miron, Meir Wilchek, Ofer Lider, Sharon Ganor, David Mirelman, Aharon Rabinkov, Uri Sela, Iris Hecht
Publikováno v:
Immunology. 111:391-399
Allicin, a major ingredient of fresh garlic extract that is produced during the crushing of garlic cloves, exerts various beneficial biological effects, including a broad spectrum of antimicrobial activity, antihyperlipidaemic and antihypertensive ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ceaaa40256a12fa93a8b9e70ad718fc
https://doi.org/10.1111/j.0019-2805.2004.01841.x
https://doi.org/10.1111/j.0019-2805.2004.01841.x