Ubiquitination of acetyltransferase Gcn5 contributes to fungal virulence in Fusarium graminearum

Autor: Ahai Chen, Yifan Zhou, Yiyi Ren, Chao Liu, Xingmin Han, Jing Wang, Zhonghua Ma, Yun Chen

Publikováno v: mBio, Vol 14, Iss 4 (2023)

ABSTRACT The histone acetyltransferase general control non-depressible 5 (Gcn5) plays a critical role in the epigenetic landscape and chromatin modification for regulating a wide variety of biological events. However, the post-translational regulatio

Externí odkaz: https://doaj.org/article/a36df156276249f0928167fb973b65fa

FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora

Autor: Xiao Liu, Ahai Chen, Angélica Caicedo-Casso, Guofei Cui, Mingjian Du, Qun He, Sookkyung Lim, Hang J. Kim, Christian I. Hong, Yi Liu

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

Circadian clocks control daily rhythms of molecular and physiological activities. Here, the authors show that the interaction between proteins FRQ and CK1, rather than FRQ stability, is a major rate-limiting step in circadian period determination in

Externí odkaz: https://doaj.org/article/dbbfd0b2ae6044ad9025f01804098213

Quantum molecular dynamics simulations of the effect of secondary modes on the photoisomerization of a retinal chromophore model

Autor: Ari Pereira, Joachim Knapik, Ahai Chen, David Lauvergnat, Federica Agostini

In this paper, we report on the performance of various quantum molecu- lar dynamics simulation methods in describing the photo-induced nonadi- abatic dynamics underlying the isomerization process of the retinal chromophore in rhodopsin. We focus on p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::01d38bb9961dc22ce00309fa9383a67a
https://doi.org/10.26434/chemrxiv-2023-2kgfl

Smolyak Algorithm Adapted to a System−Bath Separation:Application to an Encapsulated Molecule with Large-AmplitudeMotions

Autor: Ahai Chen, David M. Benoit, Yohann Scribano, André Nauts, David Lauvergnat

Publikováno v: Journal of Chemical Theory and Computation
Journal of Chemical Theory and Computation, 2022, 18 (7), pp.4366-4372. ⟨10.1021/acs.jctc.2c00108⟩

A Smolyak algorithm adapted to system-bath separation is proposed for rigorous quantum simulations. This technique combines a sparse grid method with the system-bath concept in a specific configuration without limitations on the form of the Hamiltoni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ab97153b80f925d410c25ed83da37c
https://hal.science/hal-03723977/document

Retromer Is Essential for Autophagy-Dependent Plant Infection by the Rice Blast Fungus.

Autor: Wenhui Zheng, Jie Zhou, Yunlong He, Qiurong Xie, Ahai Chen, Huawei Zheng, Lei Shi, Xu Zhao, Chengkang Zhang, Qingping Huang, Kunhai Fang, Guodong Lu, Daniel J Ebbole, Guangpu Li, Naweed I Naqvi, Zonghua Wang

Publikováno v: PLoS Genetics, Vol 11, Iss 12, p e1005704 (2015)

The retromer mediates protein trafficking through recycling cargo from endosomes to the trans-Golgi network in eukaryotes. However, the role of such trafficking events during pathogen-host interaction remains unclear. Here, we report that the cargo-r

Externí odkaz: https://doaj.org/article/ff0a00698d4a43eb913082f142a1dc4a