Zobrazeno 1 - 10
of 173
pro vyhledávání: '"AhR, Aryl hydrocarbon receptor"'
Autor:
Frontiers Production Office
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/0e977794792049e1b4e58b645e933be6
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
One gene, the immunoglobulin heavy chain (IgH) gene, is responsible for the expression of all the different antibody isotypes. Transcriptional regulation of the IgH gene is complex and involves several regulatory elements including a large element at
Externí odkaz:
https://doaj.org/article/d0baa15b5bea42e690ea958c5c359bb3
Autor:
Gaku Tsuji, Akiko Hashimoto-Hachiya, Tomoyo Matsuda-Taniguchi, Ayako Takai-Yumine, Masaki Takemura, Xianghong Yan, Masutaka Furue, Takeshi Nakahara
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Interleukin (IL)-37 suppresses systemic and local inflammation. It is expressed in the epidermis, the external layer of the skin, and is decreased in inflammatory skin diseases including atopic dermatitis (AD) and psoriasis. Therefore, an agent appli
Externí odkaz:
https://doaj.org/article/9711a9cfe9414d359a155b1bb3275706
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Innate-like B cells (ILBs) are a heterogeneous population B cells which participate in innate and adaptive immune responses. This diverse subset of B cells is characterized by the expression of CD5 and has been shown to secrete high levels of immunog
Externí odkaz:
https://doaj.org/article/5660827bccf64d4ea97f9b8727080b34
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Gut immune cells have been increasingly appreciated as important players in the central nervous system (CNS) autoimmunity in animal models of multiple sclerosis (MS). Among the gut immune cells, innate lymphoid cell type 3 (ILC3) is of special intere
Externí odkaz:
https://doaj.org/article/ab3c1c0417cb41cdad7e3f63a0dc35d6
Autor:
Adaobi Amobi-McCloud, Ravikumar Muthuswamy, Sebastiano Battaglia, Han Yu, Tao Liu, Jianmin Wang, Vasanta Putluri, Prashant K. Singh, Feng Qian, Ruea-Yea Huang, Nagireddy Putluri, Takemasa Tsuji, Amit A. Lugade, Song Liu, Kunle Odunsi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The immunoregulatory enzyme, indoleamine 2,3-dioxygenase (IDO1) and the PD-1/PD-L1 axis are potent mechanisms that impede effective anti-tumor immunity in ovarian cancer. However, whether the IDO pathway regulates PD-1 expression in T cells is curren
Externí odkaz:
https://doaj.org/article/ef43952e181b43e28a4859495d8c5fc5
Autor:
Jyoti Bhuju, Kristin M. Olesen, Clarisse S. Muenyi, Tejesh S. Patel, Robert W. Read, Lauren Thompson, Omar Skalli, Qi Zheng, Elizabeth A. Grice, Carrie Hayes Sutter, Thomas R. Sutter
Publikováno v:
Toxics, Vol 9, Iss 8, p 192 (2021)
To determine the cutaneous effects of in utero and lactational exposure to the AHR ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), pregnant C57BL/6J mice were exposed by gavage to a vehicle or 5 μg TCDD/kg body weight at embryonic day 12 and epid
Externí odkaz:
https://doaj.org/article/d79d007466db47fd9f5b17e03a39b4ec
Autor:
Chengjie Shan, Wenxin Jia, Minyi Qian, Lirui Wang, Bernd Schnabl, Dalei Wu, Nan Zhang, Yinan Zhang, Danyang Zhao, Meiling Zhang, Song Yang, Yufei Zhang, Yingsheng Gao, Quan Zhang, Chuyue Pan, Xu Shen, Jun Liu, Pengpeng Cai
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 233-256 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 233-256 (2022)
Background & Aims The ligand-activated transcription factor, aryl hydrocarbon receptor (AHR) can sense xenobiotics, dietary, microbial, and metabolic cues. Roles of Ahr in intestinal epithelial cells (IECs) have been much less elucidated compared wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec51e69e7577835c46cf4ef5134d8f2
https://doi.org/10.1016/j.jcmgh.2021.08.014
https://doi.org/10.1016/j.jcmgh.2021.08.014
Autor:
Banrida Wahlang, Monika Thapa, Michael L. Merchant, Jian Jin, Sudhir Srivastava, Josiah E. Hardesty, Russell A. Prough, Shesh N. Rai, Matthew C. Cave, Kimberly Z. Head
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3806-3819 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Dioxin-like molecules have been associated with endocrine disruption and liver disease. To better understand aryl hydrocarbon receptor (AHR) biology, metabolic phenotyping and liver proteomics were performed in mice following ligand-activation or who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd0117be990219f236c36406e5afea7
https://doi.org/10.1016/j.apsb.2021.10.014
https://doi.org/10.1016/j.apsb.2021.10.014
Autor:
Liming Chen, Junjie Zhu, Lirong Zhang, Xiaochao Ma, Xueyan Shao, Pei Wang, Xiao-bo Zhong, Yifan Bao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 171-185 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The prevalence of obesity-associated conditions raises new challenges in clinical medication. Although altered expression of drug-metabolizing enzymes (DMEs) has been shown in obesity, the impacts of obese levels (overweight, obesity, and severe obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94cf0a5fdc606267df866d8be623f019
http://www.sciencedirect.com/science/article/pii/S2211383519308585
http://www.sciencedirect.com/science/article/pii/S2211383519308585