Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial.

Autor: Schilling WHK; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Mukaka M; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Callery JJ; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Llewelyn MJ; Department of Global Health and Infection, Brighton and Sussex Medical School, Brighton, United Kingdom.; Department of Microbiology and Infection, University Hospitals Sussex NHS Foundation Trust, Brighton, United Kingdom., Cruz CV; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Dhorda M; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Ngernseng T; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Waithira N; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Ekkapongpisit M; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Watson JA; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam., Chandna A; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Cambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia., Nelwan EJ; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.; Division of Tropical Medicine and Infectious Diseases, Department of Internal Medicine, Dr. Cipto Mangukusumo Hospital, Jakarta, Indonesia., Hamers RL; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Clinical Research Unit Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia., Etyang A; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Beg MA; Department of Pathology and Laboratory Medicine, The Aga Khan University Hospital, Karachi, Pakistan., Sow S; Centre pour le Développement des Vaccins (CVD-Mali), Bamako, Mali., Yavo W; Centre de Recherche et de Lutte contre le Paludisme, Institut National de Santé Publique, Abidjan, Côte d'Ivoire., Allabi AC; Faculty of Health Sciences, Laboratory of Pharmacology and Toxicology, University of Abomey-Calavi, Cotonou, Benin., Basnyat B; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Clinical Research Unit Nepal, Lalitpur, Nepal., Sharma SK; B.P. Koirala Institute of Health Sciences (BPKIHS), Dharan, Nepal., Amofa-Sekyi M; Zambart, University of Zambia School of Public Health, Lusaka, Zambia., Yonga P; Fountain Health Care Hospital, Fountain Projects and Research Office (FOPRO), Eldoret, Kenya., Adler A; Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom., Yuentrakul P; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Cope T; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Thaipadungpanit J; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Rienpradub P; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Imwong M; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Abdad MY; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Blacksell SD; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Tarning J; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Goudjo FF; Coordination of Allada Ze Toffo Health Zone, Adjian, Benin., Dossou AD; National Public Health Laboratory, Cotonou, Benin., Konaté-Touré A; Centre de Recherche et de Lutte contre le Paludisme, Institut National de Santé Publique, Abidjan, Côte d'Ivoire., Assi SB; Institut Pierre Richet, Institut National de Santé, Publique, Bouaké, Côte d'Ivoire., Ouffoué K; Centre Hospitalier Universitaire (CHU) de Bouaké, Bouaké, Côte d'Ivoire., Nasronudin N; Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.; Universitas Airlangga Teaching Hospital, Universitas Airlangga, Surabaya, Indonesia., Rachman BE; Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.; Universitas Airlangga Teaching Hospital, Universitas Airlangga, Surabaya, Indonesia., Romadhon PZ; Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.; Universitas Airlangga Teaching Hospital, Universitas Airlangga, Surabaya, Indonesia., Dewanto DD; Husada Utama Hospital, Surabaya, Indonesia., Heryana MO; Husada Utama Hospital, Surabaya, Indonesia., Novi T; Husada Utama Hospital, Surabaya, Indonesia., Pasaribu AP; Faculty of Medicine, Universitas Sumatra Utara, Medan, Indonesia., Mutiara M; Murni Teguh Hospital, Medan, Medan, Indonesia., Nasution MPR; Murni Teguh Hospital, Medan, Medan, Indonesia., Khairunnisa K; Murni Teguh Hospital, Medan, Medan, Indonesia., Dalimunthe FA; Faculty of Medicine, Universitas Sumatra Utara, Medan, Indonesia., Airlangga E; Bunda Thamrin Hospital, Medan, Indonesia., Fahrezzy A; Bunda Thamrin Hospital, Medan, Indonesia., Subronto Y; Department of Internal Medicine, Faculty of Medicine, Public Health And Nursing, Universitas Gadjah Mada/ Dr. Sardjito Hospital, Yogyakarta, Indonesia., Ananda NR; Dr. Sardjito Hospital, Yogyakarta, Indonesia., Rahardjani M; Oxford University Clinical Research Unit Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia., Rimainar A; Oxford University Clinical Research Unit Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia., Lucinde RK; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Timbwa M; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Onyango OE; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Agutu C; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Akech S; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Hamaluba M; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Kipyego J; Fountain Health Care Hospital, Fountain Projects and Research Office (FOPRO), Eldoret, Kenya., Ngachi O; Fountain Health Care Hospital, Fountain Projects and Research Office (FOPRO), Eldoret, Kenya., Haidara FC; Centre pour le Développement des Vaccins (CVD-Mali), Bamako, Mali., Traoré OY; Centre pour le Développement des Vaccins (CVD-Mali), Bamako, Mali., Diarra F; Centre pour le Développement des Vaccins (CVD-Mali), Bamako, Mali., Khanal B; B.P. Koirala Institute of Health Sciences (BPKIHS), Dharan, Nepal., Dahal P; B.P. Koirala Institute of Health Sciences (BPKIHS), Dharan, Nepal., Shrestha S; Oxford University Clinical Research Unit Nepal, Lalitpur, Nepal., Rijal S; Oxford University Clinical Research Unit Nepal, Lalitpur, Nepal., Kabore Y; Epicentre, Niamey, Niger., Adehossi E; Université Abdou Moumouni de Niamey, Faculté des Science de la Santé, Niamey, Niger., Guindo O; Epicentre, Niamey, Niger., Qamar FN; Department of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan., Kazi AM; Department of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan., Woodrow CJ; Infectious Diseases Department, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, United Kingdom.; University of Oxford, Medical Sciences Division, John Radcliffe Hospital, Oxford, United Kingdom., Laird S; University Hospitals of Coventry and Warwickshire NHS Trust, Coventry, United Kingdom., Cheeba M; Zambart, University of Zambia School of Public Health, Lusaka, Zambia., Ayles H; Zambart, University of Zambia School of Public Health, Lusaka, Zambia.; Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom., Cheah PY; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Taylor WRJ; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Batty EM; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Chotivanich K; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Pukrittayakamee S; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., Phumratanaprapin W; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand., von Seidlein L; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Dondorp A; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Day NPJ; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., White NJ; Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

Publikováno v: PLoS medicine [PLoS Med] 2024 Sep 12; Vol. 21 (9), pp. e1004428. Date of Electronic Publication: 2024 Sep 12 (Print Publication: 2024).

Modeling the Impact of HIV-1 Nucleic Acid Testing Among Symptomatic Adult Outpatients in Kenya.

Autor: Hamilton DT; Center for Studies in Demography and Ecology, University of Washington, Seattle, WA., Agutu C; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Babigumira JB; Departments of Global Health and Pharmacy ; and., van der Elst E; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Hassan A; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Gichuru E; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Mugo P; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya., Farquhar C; Medicine, Global Health, and Epidemiology, University of Washington, Seattle, WA., Ndung'u T; Africa Health Research Institute, Durban, South Africa., Sirengo M; National AIDS and STI Control Programme, Nairobi, Kenya., Chege W; National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD., Goodreau SM; Departments of Anthropology and Epidemiology; and., Elder A; Biostatistics, University of Washington, Seattle, WA; and., Sanders EJ; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.; University of Oxford, Headington, United Kingdom., Graham SM; Medicine, Global Health, and Epidemiology, University of Washington, Seattle, WA.

Publikováno v: Journal of acquired immune deficiency syndromes (1999) [J Acquir Immune Defic Syndr] 2022 Aug 15; Vol. 90 (5), pp. 553-561. Date of Electronic Publication: 2022 May 05.

Modeling the impact of different PrEP targeting strategies combined with a clinic-based HIV-1 nucleic acid testing intervention in Kenya.

Autor: Hamilton DT; Center for Studies in Demography & Ecology, University of Washington, Seattle, WA, United States. Electronic address: dth2@uw.edu., Agutu C; KEMRI - Wellcome Trust Research Programme, Kilifi, Kenya., Sirengo M; National AIDS & STI Control Programme, Nairobi, Kenya., Chege W; National Institutes of Allergy & Infectious Diseases, National Institutes of Health, Rockville, MD, United States., Goodreau SM; Departments of Anthropology and Epidemiology, University of Washington, Seattle, WA, United States., Elder A; Department of Biostatistics, University of Washington, Seattle, WA, United States., Sanders EJ; KEMRI - Wellcome Trust Research Programme, Kilifi, Kenya; University of Oxford, Headington, United Kingdom., Graham SM; Departments of Medicine, Global Health, and Epidemiology, University of Washington, Seattle, WA, United States.

Publikováno v: Epidemics [Epidemics] 2023 Sep; Vol. 44, pp. 100696. Date of Electronic Publication: 2023 Jun 27.

Raltegravir-intensified initial antiretroviral therapy in advanced HIV disease in Africa: A randomised controlled trial

Autor: Kityo, C, Szubert, AJ, Siika, A, Heyderman, R, Bwakura-Dangarembizi, M, Lugemwa, A, Mwaringa, S, Griffiths, A, Nkanya, I, Kabahenda, S, Wachira, S, Musoro, G, Rajapakse, C, Etyang, T, Abach, J, Spyer, MJ, Wavamunno, P, Nyondo-Mipando, L, Chidziva, E, Nathoo, K, Klein, N, Hakim, J, Gibb, DM, Walker, AS, Pett, SL, Mugyenyi, P, Musiime, V, Nambi, E, Ocitti, P, Ndigendawani, M, Kemigisa, M, Acen, J, Olebo, D, Mpamize, G, Amone, A, Okweny, D, Mbonye, A, Nambaziira, F, Rweyora, A, Kangah, M, Kabaswahili, V, Abongomera, G, Omongin, J, Aciro, I, Philliam, A, Arach, B, Ocung, E, Amone, G, Miles, P, Adong, C, Tumsuiime, C, Kidega, P, Otto, B, Apio, F, Baleeta, K, Mukuye, A, Abwola, M, Ssennono, F, Baliruno, D, Tuhirwe, S, Namisi, R, Kigongo, F, Kikyonkyo, D, Mushahara, F, Tusiime, J, Musiime, A, Nankya, A, Atwongyeire, D, Sirikye, S, Mula, S, Noowe, N, Kasozi, M, Mwebe, S, Atwine, L, Senkindu, T, Natuhurira, T, Katemba, C, Ninsiima, E, Acaku, M, Kyomuhangi, J, Ankunda, R, Tukwasibwe, D, Ayesiga, L, Reid, A, Mhute, T, Tinago, GC, Bhiri, J, Mudzingwa, S, Phiri, M, Steamer, J, Nhema, R, Warambwa, C, Mutsai, S, Nemasango, B, Moyo, C, Chitongo, S, Rashirai, K, Vhembo, S, Mlambo, B, Nkomani, S, Ndemera, B, Willard, M, Berejena, C, Musodza, Y, Matiza, P, Mudenge, B, Guti, V, Etyang, A, Agutu, C, Berkley, J, Maitland, K, Njuguna, P, Awuondo, K, Wale, S, Shangala, J, Kithunga, J, Mwarumba, S, Maitha, SS, Mutai, R, Lewa, ML, Mwambingu, G, Mwanzu, A, Kalama, C, Latham, H, Shikuku, J, Fondo, A, Njogu, A, Khadenge, C, Mwakisha, B, Wools-Kaloustian, K, Nyandiko, W, Cheruiyot, P, Sudoi, A, Meli, B, Karoney, M, Nzioka, A, Tanui, M, Mokaya, M, Ekiru, W, Mboya, C, Mwimali, D, Mengich, C, Choge, J, Injera, W, Njenga, K, Cherutich, S, Orido, MA, Lwande, GO, Rutto, P, Mudogo, A, Kutto, I, Shali, A, Jaika, L, Jerotich, H, Pierre, M, Mallewa, J, Kaunda, S, Van Oosterhout, J, O'Hare, B, Heydermann, R, Gonzalez, C, Dzabala, N, Kelly, C, Denis, B, Selemani, G, Mipando, LN, Chirwa, E, Banda, P, Mvula, L, Msuku, H, Ziwoya, M, Manda, Y, Nicholas, S, Masesa, C, Mwalukomo, T, Makhaza, L, Sheha, I, Bwanali, J, Limbuni, M

Background In sub-Saharan Africa, individuals infected with HIV who are severely immunocompromised have high mortality (about 10%) shortly after starting antiretroviral therapy (ART). This group also has the greatest risk of morbidity and mortality a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::76c8634db5b063d7f9a222c5f8130b9d
http://hdl.handle.net/10044/1/90457

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