Abstract P5-13-32: Mucin 4 expression in high risk breast cancer: Predicting and overcoming resistance to immunotherapy

Autor: Roxana Schillaci, Sofia Bruni, Florencia Mauro, María F Mercogliano, Agustina Roldan-Deamicis, Cecilia J Proietti, Rosalía Cordo-Russo, Gloria Inurrigarro, Agustina Dupont, Carla Adami, Daniel Lopez Della Vecchia, Sabrina Barchuck, Silvina Figurelli, Ernesto Gil Deza, Sandra Ares, Felipe G Gercovich, Patricia V Elizalde

Publikováno v: Cancer Research. 82:P5-13

Background HER2-positive (+) and triple negative breast cancer (TNBC) have the worst survival among BC. BC patients are treated with chemotherapy (CT) and/or radiotherapy (RT), and HER2+ BC patients also receive targeted therapies, such as trastuzuma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ea5a7e8d26549966ddc698723e940da
https://doi.org/10.1158/1538-7445.sabcs21-p5-13-32

ODP438 Canonical and Non-canonical Function of EZH2 in Progesterone Receptor Target Genes in Breast Cancer

Autor: Patricia Elizalde, Martina Belmonte, Mauro Cenciarini, Agustina Roldan Deamicis, Santiago Madera, Florencia Mercogliano, Florencia Mauro, Sofia Bruni, Rosalía Cordo Russo, Roxana Schillaci, Cecilia Proietti

Publikováno v: Journal of the Endocrine Society. 6:A719-A719

Enhancer of Zeste homolog 2 (EZH2) is a histone methyltransferase which catalyzes the trimethylation of lysine 27 of histone H3 (H3K27me3), an epigenetic mark associated with chromatin compaction and transcriptional repression of target genes. This c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2bc5d35f8cc95dc0f93f1429a510bf9
https://doi.org/10.1210/jendso/bvac150.1481

Maitake Pro4X has anti-cancer activity and prevents oncogenesis in BALBc mice

Autor: Eliana Noelia Alonso, Agustina Roldan-Deamicis, Belén Brie, Gabriela Andrea Balogh, Diego Aguilera Braico

Publikováno v: Cancer Medicine. 2016, 5(9):2427–2441
Repositorio Institucional (UCA)
Pontificia Universidad Católica Argentina
instacron:UCA
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Cancer Medicine

The understanding of the molecular mechanisms of the immune tolerance induced by the tumoral microenvironment is fundamental to prevent cancer development or to treat cancer patients using immunotherapy. Actually, there are investigations about "addr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6c2cd33f1c78fa0c225ced7846f5cf
https://repositorio.uca.edu.ar/handle/123456789/14225