Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Agustin D. Martinez"'
Autor:
Fernanda M. Rozas-Villanueva, Viviana P. Orellana, Rodrigo Alarcón, Jaime Maripillan, Agustin D. Martinez, Ivan E. Alfaro, Mauricio A. Retamal
Publikováno v:
Cells, Vol 13, Iss 13, p 1150 (2024)
Background: Extravillous trophoblasts (EVTs) form stratified columns at the placenta–uterus interface. In the closest part to fetal structures, EVTs have a proliferative phenotype, whereas in the closest part to maternal structures, they present a
Externí odkaz:
https://doaj.org/article/d0113118426c43eea9903d6e5448bf3f
Autor:
Guoqiang Zhong, Nazem Akoum, Daniel A. Appadurai, Volodya Hayrapetyan, Osman Ahmed, Agustin D. Martinez, Eric C. Beyer, Alonso P. Moreno
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
In cardiac tissues, the expression of multiple connexins (Cx40, Cx43, Cx45, and Cx30.2) is a requirement for proper development and function. Gap junctions formed by these connexins have distinct permeability and gating mechanisms. Since a single cel
Externí odkaz:
https://doaj.org/article/92bbe9bcf95544a59704fc7268fe51c8
Autor:
Fanny eMomboisse, María José Olivares, Ximena eBáez-Matus, María José Guerra, Carolina eFlores-Muñoz, Juan C. Sáez, Agustin D. Martinez, Ana M. Cárdenas
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Chromaffin cells of the adrenal gland medulla synthesize and store hormones and peptides, which are released into the blood circulation in response to stress. Among them, adrenaline is critical for the fight-or-flight response. This neurosecretory pr
Externí odkaz:
https://doaj.org/article/bd56bf63dd624ec6a00c2737b6d499a0
Autor:
Evira Cortese, Alfredo Herrera, Virginia Olivares, Juan C. Maas, Ursula Zelada, Gloria Ribalta, Gabriela Vergara, Cristian Papuzinski, Javiera Herrada, Agustin D. Martinez, Helmuth A. Sanchez
Publikováno v:
Auditio ; Vol. 6 (2022); e82
Auditio; Vol. 6 (2022); e82
Auditio
instname
Auditio; Vol. 6 (2022); e82
Auditio
instname
Background. Evidence-based information on genetic sensorineural hearing loss in Latin America is limited, hindering the advancement of related clinical practice and the development of relevant healthcare policies in the field. This study describes so
Autor:
Felipe Villanelo, Peter J. Minogue, Jaime Maripillán, Mauricio Reyna-Jeldes, Joaquin Jensen-Flores, Isaac E. García, Eric C. Beyer, Tomás Pérez-Acle, Viviana M. Berthoud, Agustín D. Martínez
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-18 (2024)
Abstract Background Members of the β-subfamily of connexins contain an intracellular pocket surrounded by amino acid residues from the four transmembrane helices. The presence of this pocket has not previously been investigated in members of the α-
Externí odkaz:
https://doaj.org/article/06defa631d704d8c9d7c419ba703475f
Autor:
Chidinma Adanna Okolo, Jack Jonathan Maran, Amy Watts, Jaime Maripillan, Maria Harkiolaki, Agustín D. Martínez, Colin R. Green, Odunayo Omolola Mugisho
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e27888- (2024)
Non-junctional connexin43 (Cx43) plasma membrane hemichannels have been implicated in several inflammatory diseases, particularly playing a role in ATP release that triggers activation of the inflammasome. Therapies targeting the blocking of the hemi
Externí odkaz:
https://doaj.org/article/e17a063b57c24edb96e75c070ffc7e0f
Autor:
Oscar Jara, Jaime Maripillán, Fanny Momboisse, Ana María Cárdenas, Isaac E. García, Agustín D. Martínez
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7246 (2024)
Connexins (Cxs) are transmembrane proteins that assemble into gap junction channels (GJCs) and hemichannels (HCs). Previous researches support the involvement of Rho GTPases and actin microfilaments in the trafficking of Cxs, formation of GJCs plaque
Externí odkaz:
https://doaj.org/article/9ba926a964484e14aa81a6579f880d2e
Autor:
Ana C. Abbott, Isaac E. García, Felipe Villanelo, Carolina Flores-Muñoz, Ricardo Ceriani, Jaime Maripillán, Joel Novoa-Molina, Cindel Figueroa-Cares, Tomas Pérez-Acle, Juan C. Sáez, Helmuth A. Sánchez, Agustín D. Martínez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Some mutations in gap junction protein Connexin 26 (Cx26) lead to syndromic deafness, where hearing impairment is associated with skin disease, like in Keratitis Ichthyosis Deafness (KID) syndrome. This condition has been linked to hyperactivity of c
Externí odkaz:
https://doaj.org/article/4a2519a57af545099c4f91f689d29670
Autor:
Alvaro O. Ardiles, Carolina eFlores-Muñoz, Gabriela eToro-Ayala, Ana María Cárdenas, Adrian G Palacios, Pablo eMuñoz, Marco eFuenzalida, Juan C Saez, Agustin D Martinez
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
The threshold for bidirectional modification of synaptic plasticity is known to be controlled by several factors, including the balance between protein phosphorylation and dephosphorylation, postsynaptic free Ca(2+) concentration and NMDA receptor (N
Autor:
Francisca García-Rojas, Carolina Flores-Muñoz, Odra Santander, Pamela Solis, Agustín D. Martínez, Álvaro O. Ardiles, Marco Fuenzalida
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 887 (2023)
Pannexin-1 (Panx1) hemichannel is a non-selective transmembrane channel that may play important roles in intercellular signaling by allowing the permeation of ions and metabolites, such as ATP. Although recent evidence shows that the Panx1 hemichanne
Externí odkaz:
https://doaj.org/article/8ecaa2306d264fb7b9d02fe0f0e00e12