Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Agustin Cerani"'
Autor:
Michael Kreuter, Nils Picker, Larissa Schwarzkopf, Severin Baumann, Agustin Cerani, Roelien Postema, Ulf Maywald, Axel Dittmar, Jonathan Langley, Haridarshan Patel
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a progressive form of fibrosing interstitial pneumonia with poor survival. This study provides insight into the epidemiology, cost, and disease course of IPF in Germany. Methods A cohort of i
Externí odkaz:
https://doaj.org/article/5d0a5e8f38574cec993f52ba513c8cc9
Autor:
Yiheng Chen, Tianyuan Lu, Ulrika Pettersson-Kymmer, Isobel D. Stewart, Guillaume Butler-Laporte, Tomoko Nakanishi, Agustin Cerani, Kevin Y. H. Liang, Satoshi Yoshiji, Julian Daniel Sunday Willett, Chen-Yang Su, Parminder Raina, Celia M. T. Greenwood, Yossi Farjoun, Vincenzo Forgetta, Claudia Langenberg, Sirui Zhou, Claes Ohlsson, J. Brent Richards
Publikováno v:
Nat Genet
Metabolic processes can influence disease risk and provide therapeutic targets. By conducting genome-wide association studies of 1,091 blood metabolites and 309 metabolite ratios, we identified associations with 690 metabolites at 248 loci; and assoc
Autor:
Maya H Buch, Gerd R Burmester, Xavier Mariette, Christina Charles-Schoeman, Vijay Rajendran, Pieter-Jan Stiers, Agustin Cerani, Paul Van Hoek, Katrien Van Beneden, Yoshiya Tanaka, Hendrik Schulze-Koops, René Westhovens, Ennio Favalli
Publikováno v:
Rheumatology. 62
Background/Aims The safety profile of filgotinib (FIL), a second-generation oral Janus kinase (JAK) 1 preferential inhibitor approved in Europe, Japan, and the UK for treatment of rheumatoid arthritis (RA) has been reported. In patients (pts) with ac
Autor:
Karl Smith-Byrne, Agustin Cerani, Florence Guida, Sirui Zhou, Antonio Agudo, Krasimira Aleksandrova, Aurelio Barricarte, Miguel Rodríguez Barranco, Christoph H. Bochers, Inger Torhild Gram, Jun Han, Christopher I. Amos, Rayjean J. Hung, Kjell Grankvist, Therese Haugdhal Nøst, Liher Imaz, María Dolores Chirlaque-López, Mikael Johansson, Rudolf Kaaks, Tilman Kühn, Richard M. Martin, James D. McKay, Valeria Pala, Hilary A. Robbins, Torkjel M. Sandanger, David Schibli, Matthias B. Schulze, Ruth C. Travis, Paolo Vineis, Elisabete Weiderpass, Paul Brennan, Mattias Johansson, J. Brent Richards
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Smith Byrne, K, Martin, R M, Richards, B & Johansson, M 2022, ' Circulating Isovalerylcarnitine and Lung Cancer Risk : Evidence from Mendelian Randomization and Pre-Diagnostic Blood Measurements ', Cancer Epidemiology, Biomarkers and Prevention, vol. 31, no. 10, EPI-21-1033, pp. 1966-1974 . https://doi.org/10.1158/1055-9965.EPI-21-1033
Smith Byrne, K, Martin, R M, Richards, B & Johansson, M 2022, ' Circulating Isovalerylcarnitine and Lung Cancer Risk : Evidence from Mendelian Randomization and Pre-Diagnostic Blood Measurements ', Cancer Epidemiology, Biomarkers and Prevention, vol. 31, no. 10, EPI-21-1033, pp. 1966-1974 . https://doi.org/10.1158/1055-9965.EPI-21-1033
Background: Tobacco exposure causes 8 of 10 lung cancers, and identifying additional risk factors is challenging due to confounding introduced by smoking in traditional observational studies. Materials and Methods: We used Mendelian randomization (MR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e9faeb07bef8d811adec87c3e5f0f4
https://hdl.handle.net/10037/27964
https://hdl.handle.net/10037/27964
Autor:
Michael Kreuter, Nils Picker, Larissa Schwarzkopf, Severin Baumann, Agustin Cerani, Roelien Postema, Ulf Maywald, Axel Dittmar, Jonathan Langley, Haridarshan Patel
Publikováno v:
Respir. Res. 23:62 (2022)
Background Idiopathic pulmonary fibrosis (IPF) is a progressive form of fibrosing interstitial pneumonia with poor survival. This study provides insight into the epidemiology, cost, and disease course of IPF in Germany. Methods A cohort of incident p
Autor:
Khalil Miloudi, Agnieszka Dejda, Przemyslaw Sapieha, Manuel Buscarlet, Katie Bentley, Gael Cagnone, Catherine Ménard, Vera Guber, Bruno Larrivée, Nicolas Tetreault, Malika Oubaha, Agustin Cerani, Flavio A. Rezende, Rony Chidiac, Ariel M. Wilson, Jean-Philippe Gratton, Gaelle Mawambo, Sergio Crespo-Garcia, Jean-Sebastien Joyal, Frédérick A. Mallette, Francois Binet, Chantal Delisle
Publikováno v:
Proceedings of the National Academy of Sciences. 116:4538-4547
Diabetic macular edema is a major complication of diabetes resulting in loss of central vision. Although heightened vessel leakiness has been linked to glial and neuronal-derived factors, relatively little is known on the mechanisms by which mature e
Autor:
Vincenzo Forgetta, Olivia C. Leavy, Ivana V. Yang, Tomoko Nakanishi, Agustin Cerani, Richard J. Allen, R. Gisli Jenkins, J. Brent Richards, David A. Schwartz, Paul J. Wolters, Louise V. Wain, Masaru Koido, Sirui Zhou, G. Mark Lathrop, Deborah Assayag
Publikováno v:
The European respiratory journal. 59(2)
BackgroundIdiopathic pulmonary fibrosis (IPF) is a progressive, fatal fibrotic interstitial lung disease. Few circulating biomarkers have been identified to have causal effects on IPF.MethodsTo identify candidate IPF-influencing circulating proteins,
Autor:
Catherine Ménard, Sullivan Henriques, Agnieszka Dejda, Przemyslaw Sapieha, Nathalie Labrecque, Felix Beaudoin, Khalil Miloudi, Flavio A. Rezende, Agustin Cerani, Naoufal Akla, Salix Boulet, Jean-Sébastien Delisle, Malika Oubaha, Gaelle Mawambo, Jean-François Daudelin, Andreas Stahl, Zhuo Shao
Publikováno v:
Journal of Clinical Investigation. 124:4807-4822
Immunological activity in the CNS is largely dependent on an innate immune response and is heightened in diseases, such as diabetic retinopathy, multiple sclerosis, amyotrophic lateral sclerosis, and Alzheimer’s disease. The molecular dynamics gove
Autor:
Alireza, Moayyeri, Ching-Lung, Cheung, Kathryn Cb, Tan, John A, Morris, Agustin, Cerani, Robert P, Mohney, J Brent, Richards, Christopher, Hammond, Tim D, Spector, Cristina, Menni
Publikováno v:
Journal of Bone and Mineral Research
The metabolic state of the body can be a major determinant of bone health. We used a Mendelian randomization approach to identify metabolites causally associated with bone mass to better understand the biological mechanisms of osteoporosis. We tested
Autor:
John A. Morris, Vincenzo Forgetta, Karl Michaëlsson, Katerina Trajanoska, Agustin Cerani, Susanna C. Larsson, J. Brent Richards, Fernando Rivadeneira, Sirui Zhou
Publikováno v:
The BMJ
BMJ-British medical journal, 366:l4410. BMJ Publishing Group
BMJ-British medical journal, 366:l4410. BMJ Publishing Group
Objective To determine if genetically increased serum calcium levels are associated with improved bone mineral density and a reduction in osteoporotic fractures. Design Mendelian randomisation study. Setting Cohorts used included: the UK Biobank coho