Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Agustín Sola Carvajal"'
Autor:
Gwladys Revêchon, Nikenza Viceconte, Tomás McKenna, Agustín Sola Carvajal, Peter Vrtačnik, Peter Stenvinkel, Torbjörn Lundgren, Kjell Hultenby, Irene Franco, Maria Eriksson
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Accumulation of progerin is believed to underlie the pathophysiology of Hutchinson-Gilford progeria syndrome, a disease characterized by clinical features suggestive of premature aging, including loss of subcutaneous white adipose tissue (sW
Externí odkaz:
https://doaj.org/article/ccc79d39571149198d742b1696417602
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128917 (2015)
Hutchinson-Gilford progeria syndrome (HGPS) is a rare segmental progeroid disorder commonly caused by a point mutation in the LMNA gene that results in the increased activation of an intra-exonic splice site and the production of a truncated lamin A
Externí odkaz:
https://doaj.org/article/6a5c92e7f48d4efd8b410d2330a1d334
Autor:
Nalle Pentinmikko, Rodrigo Lozano, Sandra Scharaw, Simon Andersson, Johanna I. Englund, David Castillo-Azofeifa, Aaron Gallagher, Martin Broberg, Ki-Young Song, Agustín Sola Carvajal, Alessondra T. Speidel, Michael Sundstrom, Nancy Allbritton, Molly M. Stevens, Ophir D. Klein, Ana Teixeira, Pekka Katajisto
Publikováno v:
Science advances, vol 8, iss 41
Niche-derived factors regulate tissue stem cells, but apart from the mechanosensory pathways, the effect of niche geometry is not well understood. We used organoids and bioengineered tissue culture platforms to demonstrate that the conical shape of L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91964f32cb646181f0a860e0565d07f
https://pubmed.ncbi.nlm.nih.gov/36240269
https://pubmed.ncbi.nlm.nih.gov/36240269
Publikováno v:
Biochemical Society Transactions. 45:1279-1293
Hutchinson-Gilford progeria syndrome (HGPS, progeria) is an extremely rare premature aging disorder affecting children, with a disease incidence of ∼1 in 18 million individuals. HGPS is usually caused by a de novo point mutation in exon 11 of the L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ca10dbbdb71b640553517b19ad0256
https://doi.org/10.1042/bst20170141
https://doi.org/10.1042/bst20170141
Publikováno v:
Journal of Investigative Dermatology. 135(11):2577-2583
The nuclear lamina, a protein network located under the nuclear membrane, has during the past decade found increasing interest due to its significant involvement in a range of genetic diseases, including the segmental premature aging syndromes Hutchi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35da20458d02796ce66179b7203bac98
Autor:
Agustín Sola-Carvajal, Fernando Gil-Ortiz, Álvaro Sánchez-Ferrer, Vicente Rubio, Francisco García-Carmona
Publikováno v:
Biochemical Journal. 462:499-511
NAMDH ( N -acetyl-D-mannosamine dehydrogenase), from the soil bacteroidete Flavobacterium sp. 141-8, catalyses a rare NAD+-dependent oxidation of ManNAc ( N -acetyl-D-mannosamine) into N -acetylmannosamino-lactone, which spontaneously hydrolyses into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1bf03f1b263b7458362e5f6b9a68c7
https://doi.org/10.1042/bj20140266
https://doi.org/10.1042/bj20140266
Autor:
Agustín Sola Carvajal, María Inmaculada García García, Francisco javier García Carmona, Alvaro Sanchez Ferrer
Publikováno v:
Journal of Agricultural and Food Chemistry. 60:7450-7456
The possibility of incorporating N-acetylneuraminic acid (Neu5Ac) in infant formulas and other functional foods has opened up the need to synthesize N-acetylneuraminic acid using N-acetylneuraminate lyases (NALs) by reversible aldol condensation of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860c64224d863c33759860966095b9bc
https://doi.org/10.1021/jf3014102
https://doi.org/10.1021/jf3014102
Autor:
Agustín Sola-Carvajal, Álvaro Sánchez-Ferrer, Francisco García-Carmona, Guiomar Sánchez-Carrón, María Inmaculada García-García
Publikováno v:
Biochimie. 94:222-230
N-Acyl-D-Glucosamine 2-epimerase (AGE) catalyzes the reversible epimerization between N-acetyl-D-mannosamine (ManNAc) and N-acetyl-D-glucosamine (GlcNAc). Bacteroides ovatus ATCC 8483 shows 3 putative genes for AGE activity (BACOVA_00274, BACOVA_0179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a837cc681e68a60c7860c3457ecaf52
https://doi.org/10.1016/j.biochi.2011.10.012
https://doi.org/10.1016/j.biochi.2011.10.012
Autor:
Agustín Sola-Carvajal, Guiomar Sánchez-Carrón, Álvaro Sánchez-Ferrer, Francisco García-Carmona, María Inmaculada García-García
Publikováno v:
Bioresource Technology. 102:6186-6191
N -acetyl- d -neuraminic acid aldolase, a key enzyme in the biotechnological production of N -acetyl- d -neuraminic acid (sialic acid) from N -acetyl- d -mannosamine and pyruvate, was immobilized as cross-linked enzyme aggregates (CLEAs) by precipita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587200b23e0a8101ed7fe694a6c423aa
https://doi.org/10.1016/j.biortech.2011.02.026
https://doi.org/10.1016/j.biortech.2011.02.026
Autor:
Agustín Sola-Carvajal, Guiomar Sánchez-Carrón, Álvaro Sánchez-Ferrer, Ana Belén López-Rodríguez, Sofía Jiménez-García, Francisco García-Carmona, María Inmaculada García-García
Publikováno v:
Applied and Environmental Microbiology. 77:2471-2478
N -Acetylneuraminate lyases (NALs) or sialic acid aldolases catalyze the reversible aldol cleavage of N -acetylneuraminic acid (Neu5Ac) to form pyruvate and N -acetyl- d -mannosamine (ManNAc). In nature, N -acetylneuraminate lyase occurs mainly in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f63a96336c908ab237cf9a03e4b7121
https://doi.org/10.1128/aem.02927-10
https://doi.org/10.1128/aem.02927-10