Treatment time and circadian genotype interact to influence radiotherapy side-effects. A prospective European validation study using the REQUITE cohort

Autor: Adam J. Webb, Emily Harper, Tim Rattay, Miguel E. Aguado-Barrera, David Azria, Celine Bourgier, Muriel Brengues, Erik Briers, Renée Bultijnck, Jenny Chang-Claude, Ananya Choudhury, Alessandro Cicchetti, Dirk De Ruysscher, Maria Carmen De Santis, Alison M. Dunning, Rebecca M. Elliott, Laura Fachal, Antonio Gómez-Caamaño, Sara Gutiérrez-Enríquez, Kerstie Johnson, Ramón Lobato-Busto, Sarah L. Kerns, Giselle Post, Tiziana Rancati, Victoria Reyes, Barry S. Rosenstein, Petra Seibold, Alejandro Seoane, Paloma Sosa-Fajardo, Elena Sperk, Begoña Taboada-Valladares, Riccardo Valdagni, Ana Vega, Liv Veldeman, Tim Ward, Catharine M. West, R. Paul Symonds, Christopher J. Talbot

Publikováno v: EBioMedicine, 84:104269. Elsevier
EBIOMEDICINE
Scientia

Background Circadian rhythm impacts broad biological processes, including response to cancer treatment. Evi-dence conflicts on whether treatment time affects risk of radiotherapy side-effects, likely because of differing time analyses and target tiss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423c8e9b33751444440ce217a62d3e9b
https://cris.maastrichtuniversity.nl/en/publications/919e0cac-ba07-4365-a2f9-679150c25d0f

Reply to: Comments on "(Pre)treatment risk factors for late fatigue and fatigue trajectories following radiotherapy for breast cancer".

Autor: Rosas JC; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians University, Munich, Germany., Aguado-Barrera ME; Instituto de Investigación Sanitaria de Santiago de Compostela, Fundación Pública Galega de Medicina Xenómica (FPGMX), Santiago de Compostela, Spain., Azria D; University of Montpellier, INSERM U1194 IRCM, Institut du Cancer Montpellier (ICM), Montpellier, France., Briers E; Patient advocate, Hasselt, Belgium., Elliott R; University of Manchester, Manchester, UK., Farcy-Jacquet MP; Federation Universitaire d'Oncologie Radiothérapie d'Occitanie Méditerranée, Institut du Cancer Du Gard (ICG), CHU Carémeau, Nîmes, France., Giraldo A; Radiation Oncology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Gutiérrez-Enríquez S; Hereditary Cancer Genetics Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Rancati T; Istituto Nazionale dei Tumori, Data Science Unit, Milan, Italy., Rattay T; University of Leicester, Leicester, UK., Reyes V; Radiation Oncology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Rosenstein B; Icahn School of Medicine at Mount Sinai, New York, New York, USA., De Ruysscher D; Maastro Clinic, Maastricht, The Netherlands.; KU Leuven, Leuven, Belgium., Sperk E; Universitätsmedizin Mannheim, Mannheim Cancer Center, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Stobart H; Independent Cancer Patients' Voice, London, UK., Talbot C; University of Leicester, Leicester, UK., Vega A; Instituto de Investigación Sanitaria de Santiago de Compostela, Fundación Pública Galega de Medicina Xenómica (FPGMX), Santiago de Compostela, Spain.; Biomedical Network on Rare Diseases (CIBERER), Seville, Spain., Taboada-Valladares B; Instituto de Investigación Sanitaria de Santiago de Compostela, Fundación Pública Galega de Medicina Xenómica (FPGMX), Santiago de Compostela, Spain.; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain., Veldeman L; Ghent University Hospital, Ghent, Belgium.; Ghent University, Ghent, Belgium., Ward T; NCRI CTRad Consumer, London, UK., Webb A; University of Leicester, Leicester, UK., West C; University of Manchester, Manchester, UK., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Seibold P; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Publikováno v: International journal of cancer [Int J Cancer] 2024 Feb 15; Vol. 154 (4), pp. 759-761. Date of Electronic Publication: 2023 Oct 31.

Large-scale meta-genome-wide association study reveals common genetic factors linked to radiation-induced acute toxicities across cancer types.

Autor: Naderi E; Department of Epidemiology, University Medical Center Groningen, Groningen, The Netherlands.; Department of Radiation Oncology, University Medical Center Groningen, Groningen, The Netherlands.; Center for Statistical Genetics, Gertrude H. Sergievsky Center, and the Department of Neurology, Columbia University Medical Center, New York, NY, USA., Aguado-Barrera ME; Fundación Pública Galega Medicina Xenómica, Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain., Schack LMH; Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark.; Department of Oncology, Gødstrup Hospital, Herning, Denmark.; NIDO | Centre for Research and Education, Gødstrup Hospital, Herning, Denmark., Dorling L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Rattay T; Leicester Cancer Research Centre, University of Leicester, Leicester, UK., Fachal L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Summersgill H; Manchester Academic Health Science Centre, The Christie NHS Foundation Trust, Manchester, UK., Martínez-Calvo L; Fundación Pública Galega Medicina Xenómica, Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain., Welsh C; Department of Oncology, University of Cambridge, Cambridge, UK., Dudding T; Bristol Dental School, University of Bristol, Bristol, UK.; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Odding Y; Bristol Cancer Institute, University Hospitals Bristol NHS Foundation Trust, Bristol, UK., Varela-Pazos A; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain., Jena R; Department of Oncology, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK., Thomson DJ; Division of Cancer Sciences, University of Manchester, Manchester, UK.; The Christie NHS Foundation Trust, Manchester, UK., Steenbakkers RJHM; Department of Radiation Oncology, University Medical Center Groningen, Groningen, The Netherlands., Dennis J; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Lobato-Busto R; Department of Medical Physics, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain., Alsner J; Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark., Ness A; Bristol Dental School, University of Bristol, Bristol, UK., Nutting C; Head and Neck Unit, The Royal Marsden Hospital, London, UK., Gómez-Caamaño A; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain.; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain., Eriksen JG; Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark., Thomas SJ; Bristol Dental School, University of Bristol, Bristol, UK., Bates AM; Department of Oncology, University of Cambridge, Cambridge, UK., Webb AJ; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK., Choudhury A; Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, Manchester, UK., Rosenstein BS; Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Taboada-Valladares B; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain.; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain., Herskind C; Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Azria D; Fédération Universitaire d'Oncologie Radiothérapie d'Occitanie Méditérranée, Département d'Oncologie Radiothérapie, ICM Montpellier, INSERM U1194 IRCM, University of Montpellier, Montpellier, France., Dearnaley DP; Division of Radiotherapy and Imaging, The Institute of Cancer Research Department, The Royal Marsden NHS Foundation Trust, London, UK., de Ruysscher D; MAASTRO Clinic, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, Netherlands., Sperk E; Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Hall E; Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, UK., Stobart H; Patient Advocate, Independent Cancer Patients' Voice, London, UK., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.; University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., De Ruyck K; Departments of Basic Medical Sciences and Radiotherapy, Ghent University Hospital, Ghent, Belgium., Veldeman L; Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium., Altabas M; Radiation Oncology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., De Santis MC; Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Farcy-Jacquet MP; Fédération Universitaire d'Oncologie Radiothérapie d'Occitanie Méditérranée, Département d'Oncologie Radiothérapie, CHU Carémeau, Nîmes, France., Veldwijk MR; Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Sydes MR; MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK., Parliament M; Division of Radiation Oncology, Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, AB, Canada., Usmani N; Division of Radiation Oncology, Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, AB, Canada., Burnet NG; The Christie NHS Foundation Trust, Manchester, UK., Seibold P; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany., Symonds RP; Cancer Research Centre, University of Leicester, Leicester, UK., Elliott RM; Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, Manchester, UK., Bultijnck R; Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium., Gutiérrez-Enríquez S; Hereditary Cancer Genetics Group, Vall d'Hebron Institute of Oncology, Vall d'Hebron Hospital Campus, Barcelona, Spain., Mollà M; Radiation Oncology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Gulliford SL; Department of Medical Physics and Biomedical Engineering, University College London, UK., Green S; Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Rancati T; Data Science Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Reyes V; Radiation Oncology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Carballo A; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain.; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain., Peleteiro P; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain.; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain., Sosa-Fajardo P; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain.; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain., Parker C; Department of Medical Physics and Biomedical Engineering, University College London, UK., Fonteyne V; Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium., Johnson K; Leicester Cancer Research Centre, University of Leicester, Leicester, UK., Lambrecht M; Radiation Oncology, KU Leuven, Leuven, Belgium., Vanneste B; Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium.; Department of Radiation Oncology (Maastro Clinic), GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands., Valdagni R; Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.; Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Giraldo A; Radiation Oncology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Ramos M; Radiation Oncology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Diergaarde B; Department of Human Genetics, School of Public Health, University of Pittsburgh, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Liu G; Princess Margaret Cancer Centre, Temerty Faculty of Medicine, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada., Leal SM; Center for Statistical Genetics, Gertrude H. Sergievsky Center, and the Department of Neurology, Columbia University Medical Center, New York, NY, USA.; Taub Institute for Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA., Chua MLK; Division of Radiation Oncology, National Cancer Centre Singapore, Singapore.; Duke-NUS Medical School, Oncology Academic Clinical Programme, Singapore., Pring M; Bristol Dental School, University of Bristol, Bristol, UK., Overgaard J; Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark., Cascallar-Caneda LM; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain., Duprez F; Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium., Talbot CJ; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK., Barnett GC; Department of Oncology, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Vega A; Fundación Pública Galega Medicina Xenómica, Santiago de Compostela, Spain.; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain.; Grupo de Medicina Xenómica, Centro de Investigación Biomédica en Red de Enfermedades Raras, Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Andreassen CN; Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark.; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark., Langendijk JA; Department of Radiation Oncology, University Medical Center Groningen, Groningen, The Netherlands., West CML; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie NHS Foundation Trust Hospital, Manchester, UK., Alizadeh BZ; Department of Epidemiology, University Medical Center Groningen, Groningen, The Netherlands., Kerns SL; Department of Radiation Oncology, The Medical College of Wisconsin, Milwaukee, WI, USA.

Publikováno v: JNCI cancer spectrum [JNCI Cancer Spectr] 2023 Oct 31; Vol. 7 (6).

Comparison of prone and supine positioning for breast cancer radiotherapy using REQUITE data: dosimetry, acute and two years physician and patient-reported outcomes.

Autor: Vakaet V; Department of Human Structure and Repair, Ghent University, Gent, Belgium.; Department of Radiation Oncology, Ghent University Hospital, Gent, Belgium., Deseyne P; Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Bultijnck R; Department of Human Structure and Repair, Ghent University, Gent, Belgium., Post G; Department of Human Structure and Repair, Ghent University, Gent, Belgium., West C; Christie Hospital, University of Manchester, Manchester, UK., Azria D; Department of Radiation Oncology, University of Montpellier, Montpellier, France., Bourgier C; Department of Radiation Oncology, University of Montpellier, Montpellier, France., Farcy-Jacquet MP; Department of Radiation Oncology, University of Montpellier, Montpellier, France., Rosenstein B; Departments of Radiation Oncology and Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Green S; Departments of Radiation Oncology and Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., de Ruysscher D; Department of Radiation Oncology (Maastro), GROW, Maastricht University Medical Center, Maastricht, The Netherlands., Sperk E; Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany., Veldwijk M; Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany., Herskind C; Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany.; Radiation Oncology Unit 1, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., De Santis MC; Radiation Oncology Unit 1, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Rancati T; Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Giandini T; Medical Physics Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Seibold P; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Lambrecht M; Department of Radiation Oncology, UZ Leuven, Leuven, Belgium., Weltens C; Department of Radiation Oncology, UZ Leuven, Leuven, Belgium., Janssens H; Department of Radiation Oncology, UZ Leuven, Leuven, Belgium., Vega A; Instituto de Investigacion Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain., Taboada-Valladares MB; Instituto de Investigacion Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain., Aguado-Barrera ME; Instituto de Investigacion Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain., Reyes V; Radiation Oncology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Altabas M; Radiation Oncology Department, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Gutiérrez-Enríquez S; Hereditary Cancer Genetics Group, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Monten C; Department of Radiation Oncology, Ghent University Hospital, Gent, Belgium., Van Hulle H; Clinical Research Centre, AZ Sint-Jan, Brugge, Belgium., Veldeman L; Department of Human Structure and Repair, Ghent University, Gent, Belgium.; Department of Radiation Oncology, Ghent University Hospital, Gent, Belgium.

Publikováno v: Acta oncologica (Stockholm, Sweden) [Acta Oncol] 2023 Sep; Vol. 62 (9), pp. 1036-1044. Date of Electronic Publication: 2023 Aug 07.

Comparing symptom reporting by prostate cancer patients and healthcare professionals in the international multicentre REQUITE study.

Autor: Heumann P; German Cancer Research Center (DKFZ), Division of Cancer Epidemiology, Heidelberg, Germany. Electronic address: philipp.heumann@dkfz.de., Aguado-Barrera ME; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Fundación Pública Galega de Medicina Xenómica (FPGMX), Santiago de Compostela, Spain. Electronic address: miguelelias.aguado@usc.es., Avuzzi B; Department of Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: barbara.avuzzi@istitutotumori.mi.it., Azria D; Federation Universitaire d'Oncologie Radiothérapie d'Occitanie Méditerranée, Univ Montpellier, INSERM U1194 IRCM, Institut du Cancer Montpellier (ICM), Montpellier, France. Electronic address: David.Azria@icm.unicancer.fr., Briers E; Patient advocate, Hasselt, Belgium. Electronic address: erikbriers@telenet.be., Bultijnck R; Ghent University Hospital, Belgium; Ghent University, Ghent, Belgium. Electronic address: Renee.Bultijnck@ugent.be., Choudhury A; University of Manchester, Christie Hospital, Manchester, UK. Electronic address: Ananya.Choudhury@christie.nhs.uk., De Ruysscher D; Maastro Clinic, Maastricht, the Netherlands. Electronic address: dirk.deruysscher@maastro.nl., Farcy-Jacquet MP; Federation Universitaire d'Oncologie Radiothérapie d'Occitanie Méditerranée, Institut du Cancer Du Gard (ICG), CHU Carémeau, Nîmes, France. Electronic address: marie.pierre.farcy.jacquet@chu-nimes.fr., Fonteyne V; Ghent University Hospital, Belgium; Ghent University, Ghent, Belgium. Electronic address: valerie.fonteyne@uzgent.be., Gómez Caamaño A; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain. Electronic address: Antonio.Gomez.Caamano@sergas.es., Helmbold I; German Cancer Research Center (DKFZ), Division of Cancer Epidemiology, Heidelberg, Germany. Electronic address: i.helmbold@dkfz.de., Johnson K; Department of Genetics & Cancer Sciences, University of Leicester, UK. Electronic address: kerstie@gmail.com., Kerns SL; Medical College of Wisconsin, USA. Electronic address: skerns@mcw.edu., Lambrecht M; KU Leuven, Leuven, Belgium. Electronic address: maarten.lambrecht@uzleuven.be., Lingard Z; University of Manchester, Christie Hospital, Manchester, UK. Electronic address: zoe.lingard@manchester.ac.uk., Rancati T; Data Science Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: Tiziana.Rancati@istitutotumori.mi.it., Rosenstein BS; The Department of Radiation Oncology and the Department of Genetics & Genomic Sciences, Icahn School of Medicine, New York, USA. Electronic address: barry.rosenstein@mssm.edu., Sperk E; Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany. Electronic address: Elena.Sperk@medma.uni-heidelberg.de., Paul Symonds R; Department of Genetics & Cancer Sciences, University of Leicester, UK. Electronic address: rps8@le.ac.uk., Talbot C; Department of Genetics & Cancer Sciences, University of Leicester, UK. Electronic address: cjt14@leicester.ac.uk., Valdagni R; Department of Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Oncology and Hemato-Oncology, Università degli Studi di Milano, Milan, Italy. Electronic address: Riccardo.Valdagni@istitutotumori.mi.it., Vega A; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Fundación Pública Galega de Medicina Xenómica (FPGMX), Santiago de Compostela, Spain; Biomedical Network on Rare Diseases (CIBERER), Spain. Electronic address: ana.vega@usc.es., Veldeman L; Ghent University Hospital, Belgium; Ghent University, Ghent, Belgium. Electronic address: liv.veldeman@uzgent.be., Ward T; UKNCRI CTRad Consumer, UK. Electronic address: timward155@gmail.com., Webb A; Department of Genetics & Cancer Sciences, University of Leicester, UK. Electronic address: ajw51@leicester.ac.uk., West CM; University of Manchester, Christie Hospital, Manchester, UK. Electronic address: Catharine.West@manchester.ac.uk., Chang-Claude J; German Cancer Research Center (DKFZ), Division of Cancer Epidemiology, Heidelberg, Germany; University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Germany. Electronic address: j.chang-claude@dkfz.de., Seibold P; German Cancer Research Center (DKFZ), Division of Cancer Epidemiology, Heidelberg, Germany. Electronic address: p.seibold@dkfz.de.

Publikováno v: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2023 Jan; Vol. 178, pp. 109426. Date of Electronic Publication: 2022 Nov 25.